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1.发明公开公开(公告)号：US20240319208A1
公开(公告)日：2024-09-26
申请号：US18536722
申请日：2023-12-12
IPC分类号： G01N33/68 , A61K9/00 , A61K31/40 , A61K31/4025 , A61K31/422 , A61K31/505 , A61K31/506 , A61K38/12 , A61K45/06 , C12Q1/6883 , G01N33/569 , G01N33/74 , G01N33/78
CPC分类号： G01N33/6893 , A61K9/0019 , A61K31/40 , A61K31/4025 , A61K31/422 , A61K31/505 , A61K31/506 , A61K38/12 , A61K45/06 , C12Q1/6883 , G01N33/56988 , G01N33/74 , G01N33/78 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N2333/5754 , G01N2800/28 , G01N2800/347 , G01N2800/52
摘要： The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
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2.发明申请公开(公告)号：US20130252898A1
公开(公告)日：2013-09-26
申请号：US13906074
申请日：2013-05-30
IPC分类号： G01N33/68
CPC分类号： G01N33/6893 , A61K9/0019 , A61K31/40 , A61K31/4025 , A61K31/422 , A61K31/505 , A61K31/506 , A61K38/12 , A61K45/06 , C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N33/56988 , G01N33/74 , G01N33/78 , G01N2333/5754 , G01N2800/28 , G01N2800/347 , G01N2800/52
摘要： The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
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3.发明授权公开(公告)号：US11874283B2
公开(公告)日：2024-01-16
申请号：US17244214
申请日：2021-04-29
IPC分类号： A61K38/12 , G01N33/68 , G01N33/74 , A61K31/4025 , A61K45/06 , A61K9/00 , A61K31/40 , A61K31/422 , A61K31/505 , A61K31/506 , C12Q1/6883 , G01N33/569 , G01N33/78
CPC分类号： G01N33/6893 , A61K9/0019 , A61K31/40 , A61K31/4025 , A61K31/422 , A61K31/505 , A61K31/506 , A61K38/12 , A61K45/06 , C12Q1/6883 , G01N33/56988 , G01N33/74 , G01N33/78 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N2333/5754 , G01N2800/28 , G01N2800/347 , G01N2800/52
摘要： The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
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4.发明申请公开(公告)号：US20210247406A1
公开(公告)日：2021-08-12
申请号：US17244214
申请日：2021-04-29
IPC分类号： G01N33/68 , A61K38/12 , G01N33/74 , A61K31/4025 , A61K45/06 , A61K9/00 , A61K31/40 , A61K31/422 , A61K31/505 , A61K31/506 , C12Q1/6883 , G01N33/569 , G01N33/78
摘要： The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
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5.发明授权公开(公告)号：US11372005B2
公开(公告)日：2022-06-28
申请号：US17094175
申请日：2020-11-10
IPC分类号： A61K9/19 , G01N33/68 , A61K38/12 , G01N33/74 , A61K31/4025 , A61K45/06 , A61K9/00 , A61K31/40 , A61K31/422 , A61K31/505 , A61K31/506 , C12Q1/6883 , G01N33/569 , G01N33/78
摘要： The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
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