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公开(公告)号：US10414751B2
公开(公告)日：2019-09-17
申请号：US16270717
申请日：2019-02-08
IPC分类号： C07D401/06 , A61P31/10 , C07B63/04
摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.
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公开(公告)号：US10370353B2
公开(公告)日：2019-08-06
申请号：US15835991
申请日：2017-12-08
IPC分类号： C07D401/06
摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.
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公开(公告)号：US10676459B2
公开(公告)日：2020-06-09
申请号：US16545042
申请日：2019-08-20
IPC分类号： C07D401/06 , A61P31/10 , C07B63/04
摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.
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公开(公告)号：US10464921B2
公开(公告)日：2019-11-05
申请号：US15760738
申请日：2016-09-16
发明人： David Dale Wirth , Christopher M. Yates , William J. Hoekstra , Martin F. Bindl , Eduard Hartmann
IPC分类号： C07D401/06 , C07D453/02 , C07D213/30 , C07C303/44 , C07C309/30 , B01J31/02 , C07B53/00
摘要： The present invention relates to a process for preparing a compound of 5 or 5*, or a mixture thereof, that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compounds 7, 7* and 11, 11* and substituted derivatives thereof.
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公开(公告)号：US20190210994A1
公开(公告)日：2019-07-11
申请号：US16270717
申请日：2019-02-08
IPC分类号： C07D401/06 , C07B63/04 , A61P31/10
CPC分类号： C07D401/06 , A61P31/10 , C07B63/04 , C07B2200/13
摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.
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公开(公告)号：US20180319768A1
公开(公告)日：2018-11-08
申请号：US15835991
申请日：2017-12-08
IPC分类号： C07D401/06
CPC分类号： C07D401/06 , A61P31/10 , C07B63/04 , C07B2200/13
摘要： The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.
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