-
公开(公告)号：US20190161469A1
公开(公告)日：2019-05-30
申请号：US16241036
申请日：2019-01-07
申请人： Mycovia Pharmaceuticals, Inc. , The United States of America, as represented by the Secretary, Department of Health and Human Serv
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D213/38 , C07D405/06 , C07D213/26
CPC分类号： C07D401/06 , C07D213/26 , C07D213/38 , C07D405/06
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
-
公开(公告)号：US10399943B2
公开(公告)日：2019-09-03
申请号：US15126392
申请日：2015-03-19
申请人： Mycovia Pharmaceuticals, Inc. , The United States of America, as represented by the Secretary, Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D213/26 , C07D401/06 , C07D213/50 , C07D405/06 , C07D213/30 , C07D213/38
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
-
公开(公告)号：US20190177298A1
公开(公告)日：2019-06-13
申请号：US16132973
申请日：2018-09-17
申请人： Mycovia Pharmaceuticals, Inc , The U.S.A., as represented by the Secretary, Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D213/56 , C07D405/06 , C07D213/38 , C07D213/50
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
-
公开(公告)号：US11051514B2
公开(公告)日：2021-07-06
申请号：US15574775
申请日：2016-05-17
发明人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Gary D. Gustafson , Michael T. Sullenberger , Kimberly Steward , Javier Delgado , Xuelin Wang
IPC分类号： A01N43/653 , C07D401/06
摘要： The present invention relates to compounds of Formula (I): wherein R1 is as defined herein, or an acceptable salt, solvate, prodrug or hydrate thereof. The compounds of Formula I are inhibitors of metalloenzymes, such as lanosterol demethylase (CYP51).
-
公开(公告)号：US10421741B2
公开(公告)日：2019-09-24
申请号：US16030228
申请日：2018-07-09
申请人： Mycovia Pharmaceuticals, Inc. , The United States of America, as represented by the Secretary, Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D405/06 , C07D213/30 , C07D213/38 , C07D213/56 , C07D213/50
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
-
公开(公告)号：US10745378B2
公开(公告)日：2020-08-18
申请号：US16253909
申请日：2019-01-22
IPC分类号： C07D401/06 , A61K31/4439 , C07D403/06 , C07D257/04 , A61K45/06 , C07D213/30 , C07D213/50
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
-
公开(公告)号：US20190185429A1
公开(公告)日：2019-06-20
申请号：US16280527
申请日：2019-02-20
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D213/50 , C07D405/06 , C07D401/06 , C07D213/30 , C07D213/38
CPC分类号： C07D213/50 , C07D213/30 , C07D213/38 , C07D401/06 , C07D405/06
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
-
公开(公告)号：US20190010140A1
公开(公告)日：2019-01-10
申请号：US16030228
申请日：2018-07-09
申请人： Mycovia Pharmaceuticals, Inc. , The United State of America, as represented by the Secretary, Department of Health and Human Service
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D213/50 , C07D405/06 , C07D213/30 , C07D213/56 , C07D213/38
CPC分类号： C07D401/06 , C07D213/30 , C07D213/38 , C07D213/50 , C07D213/56 , C07D405/06
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
-
公开(公告)号：US20210360921A1
公开(公告)日：2021-11-25
申请号：US17338578
申请日：2021-06-03
发明人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Gary D. Gustafson , Michael T. Sullenberger , Kimberly Steward , Javier Delgado , Xuelin Wang
IPC分类号： A01N43/653 , C07D401/06
摘要： The present invention relates to compounds of Formula (I): wherein R1 is as defined herein, or an acceptable salt, solvate, prodrug or hydrate thereof. The compounds of Formula I are inhibitors of metalloenzymes, such as lanosterol demethylase (CYP51).
-
公开(公告)号：US10464921B2
公开(公告)日：2019-11-05
申请号：US15760738
申请日：2016-09-16
发明人： David Dale Wirth , Christopher M. Yates , William J. Hoekstra , Martin F. Bindl , Eduard Hartmann
IPC分类号： C07D401/06 , C07D453/02 , C07D213/30 , C07C303/44 , C07C309/30 , B01J31/02 , C07B53/00
摘要： The present invention relates to a process for preparing a compound of 5 or 5*, or a mixture thereof, that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compounds 7, 7* and 11, 11* and substituted derivatives thereof.
-
-
-
-
-
-
-
-
-
搜索结果
17 条记录 (耗时 0.034 秒)
