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1.发明授权Use of N-acetylneuraminic acid aldolase in catalytic synthesis of N-acetylneuraminic acid 有权N-乙酰神经氨酸醛缩酶在N-乙酰神经氨酸催化合成中的应用公开(公告)号：US09512420B2
公开(公告)日：2016-12-06
申请号：US14396317
申请日：2013-11-27
Applicant: Nanjing University of Technology
Inventor： Jingjing Xie , Wenyan Ji , Hanjie Ying , Wujin Sun , Ting Guo , Yong Chen , Xiaochun Chen , Jinglan Wu
CPC classification number: C12N9/88 , C12N15/63 , C12P19/26 , C12Y401/03003 , Y02P20/52
Abstract: It discloses a use of N-acetylneuraminic acid aldolase with an amino acid sequence as shown in SEQ ID NO: 2 in catalytic synthesis of N-acetylneuraminic acid. The preparation of N-acetylneuraminic acid is to use the N-acetylneuraminic acid aldolase with the amino acid sequence as shown in SEQ ID NO: 2 as a catalyst, and N-acetylmannosamine and pyruvic acid as substrates.
Abstract translation: 其公开了N-乙酰神经氨酸醛缩酶与N-乙酰神经氨酸的催化合成中具有SEQ ID NO：2所示氨基酸序列的用途。 N-乙酰神经氨酸的制备是使用N-乙酰神经氨酸醛缩酶与SEQ ID NO：2所示的氨基酸序列作为催化剂，N-乙酰甘露糖胺和丙酮酸作为底物。
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2.发明申请USE OF N-ACETYLNEURAMINIC ACID ALDOLASE IN CATALYTIC SYNTHESIS OF N-ACETYLNEURAMINIC ACID 审中-公开N-乙酰氨基酸的脱乙酰壳多糖在N-乙酰氨基酸的催化合成中的应用公开(公告)号：US20160017308A1
公开(公告)日：2016-01-21
申请号：US14396317
申请日：2013-11-27
Applicant: NANJING UNIVERSITY OF TECHNOLOGY
Inventor： Jingjing Xie , Wenyan Ji , Hanjie Ying , Wujin Sun , Ting Guo , Yong Chen , Xiaochun Chen , Jinglan Wu
IPC: C12N9/88
CPC classification number: C12N9/88 , C12N15/63 , C12P19/26 , C12Y401/03003 , Y02P20/52
Abstract: It discloses a use of N-acetylneuraminic acid aldolase with an amino acid sequence as shown in SEQ ID NO: 2 in catalytic synthesis of N-acetylneuraminic acid. The preparation of N-acetylneuraminic acid is to use the N-acetylneuraminic acid aldolase with the amino acid sequence as shown in SEQ ID NO: 2 as a catalyst, and N-acetylmannosamine and pyruvic acid as substrates.
Abstract translation: 其公开了N-乙酰神经氨酸醛缩酶与N-乙酰神经氨酸的催化合成中具有SEQ ID NO：2所示氨基酸序列的用途。 N-乙酰神经氨酸的制备是使用N-乙酰神经氨酸醛缩酶与SEQ ID NO：2所示的氨基酸序列作为催化剂，N-乙酰甘露糖胺和丙酮酸作为底物。
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