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公开(公告)号:US11952687B2
公开(公告)日:2024-04-09
申请号:US16319148
申请日:2017-01-12
发明人: Jong Young Kwak , Jung Min Kim , Yeo Jin Park , Dan Bi Park , Qasaim Muhammad , Young Hun Jeong
IPC分类号: D04H1/4309 , C12N5/00 , D01D5/00 , D01D10/02 , D01D10/06 , D04H1/728 , D06M11/11 , D06M13/127 , D06M13/402
CPC分类号: D04H1/4309 , C12N5/0068 , D01D5/003 , D01D5/0038 , D01D5/0069 , D01D10/02 , D01D10/06 , D04H1/728 , D06M11/11 , D06M13/127 , D06M13/402 , C12N2533/30
摘要: The present disclosure provides a method for producing a cell-culturing polyvinyl alcohol-based nanofiber structure, the method comprising: electrospinning an electrospun solution to form a nanofiber mat, wherein the electrospun solution contains polyvinyl alcohol (PVA), polyacrylic acid (PA) and glutaraldehyde (GA); crosslinking the nanofiber mat via a hydrochloric acid (HCl) vapor treatment; and treating the crosslinked nanofiber mat with dimethylformamide (DMF) solvent to crystallize the nanofiber mat.