-
公开(公告)号:US20210271853A1
公开(公告)日:2021-09-02
申请号:US17233046
申请日:2021-04-16
申请人: NANOLIVE SA
发明人: Yann COTTE , Sebastien EQUIS , Bastian DALLA PIAZZA , Sorin POP , Luca CLARIO , Christopher TREMBLAY , Pierre-Alain COTTE
摘要: A microscopic object characterization system comprises a computer system, a microscope with a computing unit connected to the computer system, and an object characterization program executable in the computer system configured to receive refractive index data representing at least a spatial distribution of measured values of refractive index (RI) or values correlated to refractive index of the microscopic object. The object characterization program is operable to execute an algorithm applying a plurality of transformations on the refractive index data. The transformations generate a distribution of two or more parameters used to characterize features of the microscopic object. The computer system further comprises a feedback interface configured for connection to one or more data servers in a network computing system, via a global communications network such as the internet, and configured to receive feedback data from the data servers for processing by the object characterization program to calibrate, refine or enhance a characterization of the features.
-
公开(公告)号:US20190251330A1
公开(公告)日:2019-08-15
申请号:US16309292
申请日:2017-06-12
申请人: NANOLIVE SA
发明人: Yann COTTE , Sebastien EQUIS , Bastian DALLA PIAZZA , Sorin POP , Luca CLARIO , Christopher TREMBLAY , Pierre-Alain COTTE
CPC分类号: G06K9/00147 , G01N1/30 , G06F3/04847 , G06K9/00127 , G06K9/0014 , G06T7/0012 , G06T2207/10056 , G06T2207/10064 , G06T2207/30024
摘要: Microscopic object characterization system (1), comprising a computer system (2, 2a, 2b), a microscope (4) with a computing unit (5) connected to the computer system, and an object characterization program (17) executable in the computer system configured to receive refractive index data representing at least a spatial distribution of measured values of refractive index (RI) or values correlated to refractive index of said microscopic object. The object characterization program is operable to execute an algorithm applying a plurality of transformations on said refractive index data. The transformations generate a distribution of two or more parameters used to characterize features of the microscopic object. The computer system further comprises a feedback interface configured for connection to one or more data servers in a network computing system, via a global communications network such as the internet, and configured to receive feedback data from the data servers for processing by the object characterization program to calibrate, refine or enhance a characterization of said features.
-
公开(公告)号:US20240053135A1
公开(公告)日:2024-02-15
申请号:US18257032
申请日:2021-12-13
申请人: NANOLIVE SA
发明人: Sebastien EQUIS , Yann COTTE , Pierre-Alain COTTE
IPC分类号: G01B9/02 , G01B9/02091
CPC分类号: G01B9/02047 , G01B9/02091
摘要: 34 P2418PC00 Abstract Optical diffraction tomography microscope (2) comprising an illumination system (4) configured for transmitting a sample beam through a sample observation zone, a detection 5 system (8) comprising at least one image sensor (54), and a wave collection system (6) comprising a lens (16) downstream of the sample observation zone configured for directing the sample beam towards the at least one image sensor.
-
公开(公告)号:US20200348122A1
公开(公告)日:2020-11-05
申请号:US16729888
申请日:2019-12-30
申请人: NANOLIVE SA
发明人: Yann COTTE , Pierre-Alain COTTE , Sebastien EQUIS , Andreas KERN
IPC分类号: G01B9/02 , G01N21/45 , G02B21/14 , G02B21/36 , G03H1/08 , G02B26/10 , G03H1/26 , G03H1/04 , G02B26/08
摘要: A microscope comprising a coherent light source producing a coherent light beam, a light beam guide system comprising a beam splitter configured to split the coherent light beam into a reference beam and a sample illumination beam, a sample holder configured to hold a sample to be observed, a sample illumination device configured to direct the sample illumination beam through the sample and into a microscope objective, a beam reuniter configured to reunite the reference beam and sample illumination beam after passage of the sample illumination beam through the sample to be observed, and a light sensing system configured to capture at least phase and intensity values of the coherent light beam downstream of the beam reuniter.
-
公开(公告)号:US20240044636A1
公开(公告)日:2024-02-08
申请号:US18257527
申请日:2021-12-13
申请人: NANOLIVE SA
发明人: Sebastien EQUIS , Yann COTTE , Pierre-Alain COTTE
CPC分类号: G01B9/02047 , G03H1/0005 , G02B21/06 , G03H2001/005
摘要: Optical diffraction tomography microscope (2) comprising an illumination system (4) configured for transmitting a sample beam through a sample observation zone, a detection system (8) comprising at least one image sensor (54), and a wave collection system (6) comprising a lens (16) downstream of the sample observation zone configured for directing the sample beam towards the at least one image sensor.
-
公开(公告)号:US20170299371A1
公开(公告)日:2017-10-19
申请号:US15513012
申请日:2015-09-18
申请人: NANOLIVE SA
发明人: Yann COTTE , Pierre-Alain COTTE , Sebastien EQUIS , Andreas KERN
CPC分类号: G01B9/02047 , G01B9/02068 , G01N21/453 , G02B21/14 , G02B21/367 , G02B26/0816 , G02B26/108 , G03H1/0443 , G03H1/0866 , G03H1/265 , G03H1/268 , G03H2001/0038 , G03H2001/005 , G03H2001/0456
摘要: Microscope (2) comprising a coherent light source (4) producing a coherent light beam (7), a light beam guide system (6) comprising a beam splitter (14) configured to split the coherent light beam (7) into a reference beam (7a) and a sample illumination beam (7b), a sample holder (18) configured to hold a sample (1) to be observed, a sample illumination device (28) configured to direct the sample illumination beam (7b) through the sample and into a microscope objective (37), a beam reuniter (16) configured to reunite the reference beam and sample illumination beam after passage of the sample illumination beam through the sample to be observed, and a light sensing system (8) configured to capture at least phase and intensity values of the coherent light beam downstream of the beam reuniter.
-
-
-
-
-