公开(公告)号：US09897611B2

公开(公告)日：2018-02-20

申请号：US14655792

申请日：2013-12-09

Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

Inventor： Shinya Honda ,  Hideki Watanabe ,  Kazuhiko Yamasaki

IPC: C12N7/06 ,  G01N33/68 ,  C12N15/10 ,  C07K7/06

CPC classification number: G01N33/6845 ,  C07K7/06 ,  C07K2319/00 ,  C12N15/1034 ,  C12N15/1044 ,  C12N15/1093

Abstract: Disclosed is a molecular library comprising a group of a plurality of molecules, wherein each member of the library is a polypeptide having a randomized sequence moiety and a microprotein moiety. The microprotein is a protein comprising an amino acid sequence of 30 or less amino acid residues having the ability to form a particular conformation by spontaneous folding in a solution and is, for example, chignolin comprising the amino acid sequence represented by SEQ ID NO: 1. Also, disclosed is a method for identifying a novel functional molecule using the library of the present invention.