专利检索 ap:("NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY" OR "UNIVERSITY OF TOYAMA") AND inv:"Takanori WAGATSUMA" 第 1 页

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发明申请
METHOD FOR EFFICIENTLY INDUCING ANTIBODY, ANTIBODY AND DETECTION SYSTEM FOR HEPATITIS VIRUS 有权

公开(公告)号：US20210283246A1

公开(公告)日：2021-09-16

申请号：US16972367

申请日：2019-06-06

申请人： NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY , UNIVERSITY OF TOYAMA

发明人： Hisashi NARIMATSU , Kiyohiko ANGATA , Hiroyuki KAJI , Atsushi KUNO , Takashi SATO , Yasunori CHIBA , Akira TOGAYACHI , Hiroki SHIMIZU , Maki SOGABE , Takanori WAGATSUMA , Masashi MIZOKAMI , Masaaki KORENAGA , Kazuto TAJIRI , Tatsuhiko OZAWA

IPC分类号： A61K39/29 , C07K14/005 , C07K16/08 , G01N33/576 , A61P31/20

摘要： An examination system that recognizes a glycosylated antigen in Dane particles of hepatitis B virus (HBV) and a neutralizing antibody that recognizes the glycosylated antigen and that exhibits an infection-inhibiting activity. It was elucidated that Dane particles are associated with specific glycan structures, and this enabled the construction of a new detection system for infectious, i.e., nucleic acid-containing, hepatitis B virus particles and the provision of a neutralizing antibody that recognizes a glycosylated antigen and that exhibits an infection-inhibiting activity.