Insolubilization of gelatin-containing film by citrate treatment
    2.
    发明授权
    Insolubilization of gelatin-containing film by citrate treatment 失效
    通过柠檬酸盐处理对含有凝胶膜的不溶性

    公开(公告)号:US3627695A

    公开(公告)日:1971-12-14

    申请号:US3627695D

    申请日:1969-05-05

    Applicant: NCR CO

    CPC classification number: A61K9/5057 B01J13/206 Y10T428/2984

    Abstract: A treatment process is disclosed for gelatin-containing or proteinaceous capsule wall materials and films wherein the capsules and films which include the proteinaceous materials therein are soaked or steeped in aqueous citrate solutions for extended periods of time. The citrate treatment of this invention serves to harden the capsule wall or film material in such a way as to render it water insoluble. In various embodiments of the treatment, a final capsule or film process step is included, said step differing as to the desired or required intended use of the citrate-treated films or capsule wall material. The treated films or capsule walls can be used without drying, by drying only or by drying only and then subjecting the films or capsule walls to an aging process. The treated films or capsule walls can also be finished by drying and then subjecting them to a desiccation step similar to the aging step but under different conditions.

    Enzymatic treatment of gelled proteinaceous film material
    4.
    发明授权
    Enzymatic treatment of gelled proteinaceous film material 失效
    凝胶状蛋白膜材料的酶处理

    公开(公告)号:US3639259A

    公开(公告)日:1972-02-01

    申请号:US3639259D

    申请日:1969-04-09

    Applicant: NCR CO

    CPC classification number: B01J13/20 B01J13/10 Y10T428/2984

    Abstract: A method is disclosed for treating proteinaceous films or preformed capsule walls with proteolytic enzymes to afford coldwater solubility. According to the process of this invention, preformed films or capsule walls are partially degraded enzymatically, in an aqueous vehicle, to such a degree that the degraded proteinaceous material is rendered soluble in cold water at some desired or required temperature of use. Such treatment of already made films or capsule walls is contrasted with enzymatic treatment of proteins before manufacture of the films or capsule walls themselves.

    Abstract translation: 公开了一种用蛋白质水解酶处理蛋白质膜或预制胶囊壁以提供冷水溶解度的方法。 根据本发明的方法,预处理的薄膜或胶囊壁在水性载体中被酶促部分降解,使得降解的蛋白质材料在某些所需或所需使用的温度下可溶于冷水。 已经制备的薄膜或胶囊壁的这种处理与在制造薄膜或胶囊壁本身之前的蛋白质的酶处理形成对照。

    Layered capsule walls and a method for manufacturing them
    5.
    发明授权
    Layered capsule walls and a method for manufacturing them 失效
    层状胶囊及其制造方法

    公开(公告)号:US3627693A

    公开(公告)日:1971-12-14

    申请号:US3627693D

    申请日:1970-01-28

    Applicant: NCR CO

    Abstract: A process is disclosed for performing encapsulation, en masse, in an aqueous liquid vehicle, wherein two kinds of hydrophilic polymeric material are sequentially deposited from solution onto particles of intended capsule core entities. The two kinds of hydrophilic polymeric wall materials, while individually and sequentially deposited from solution by liquid-liquid phase separation, also yield a middle-zone wherein the two kinds of material are present in a mixed combination. A preferred capsule product of this disclosed process comprises: substantially water insoluble capsule core material; polyvinyl alcohol inner capsule wall material; polyvinyl alcohol-gelatin middle-zone wall; and gelatin outer capsule wall material.

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