公开(公告)号：US10092293B2

公开(公告)日：2018-10-09

申请号：US15344998

申请日：2016-11-07

Applicant: NEOGRAFT TECHNOLOGIES, INC.

Inventor： Peter P. Zilla ,  Nasser Rafiee ,  Deon Bezuidenhout ,  Thomas Franz ,  Mark Yeoman ,  Hellmut C. Bowles ,  Nareak Douk ,  Michael F. Wolf ,  Paul Human

IPC: A61F2/06 ,  A61B17/11 ,  A61F2/07 ,  A61F2/856 ,  A61F2/90 ,  A61F2/95

Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.

公开(公告)号：US09517069B2

公开(公告)日：2016-12-13

申请号：US14448694

申请日：2014-07-31

Applicant: Neograft Technologies, Inc.

Inventor： Peter P. Zilla ,  Nasser Rafiee ,  Deon Bezuidenhout ,  Thomas Franz ,  Mark Yeoman ,  Hellmut C. Bowles ,  Nareak Douk ,  Michael F. Wolf ,  Paul Human

IPC: A61F2/06 ,  A61F2/07 ,  A61B17/11 ,  A61F2/82 ,  A61B5/107 ,  A61F2/95 ,  A61F2/90

CPC classification number: A61B17/11 ,  A61B5/1076 ,  A61B2017/1107 ,  A61B2017/1132 ,  A61B2017/1135 ,  A61B2017/1139 ,  A61F2/06 ,  A61F2/07 ,  A61F2/82 ,  A61F2/856 ,  A61F2/90 ,  A61F2/95 ,  A61F2240/002

Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.

Abstract translation: 提供支架和使用支架的方法。 本发明的支架为设置在其内的血管段提供外部支撑结构，其中支架能够以模仿动脉的顺应性的方式弹性径向扩张。 支架可以由形成的针织或编织网形成，以便提供所需的顺应性。 提供具有支架和设置在其内的静脉段的静脉移植物，其中移植物能够模拟动脉的顺应性。 提供了选择小型化支架的方法和使用本发明的支架在缩小和平滑方面的方法。 提供了用包括本发明的支架的静脉移植物代替动脉的一部分的方法。 提供了使用本发明的支架在静脉移植物中减少植入静脉段内膜增生的方法。