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    ARTIFICIAL GRAFT DEVICES AND RELATED SYSTEMS AND METHODS
    3.
    发明申请
    ARTIFICIAL GRAFT DEVICES AND RELATED SYSTEMS AND METHODS 审中-公开
    人工晶体装置及相关系统及方法

    公开(公告)号：US20160302911A1

    公开(公告)日：2016-10-20

    申请号：US15108276

    申请日：2014-12-22

    Applicant: NEOGRAFT TECHNOLOGIES, INC.

    Inventor： Lorenzo SOLETTI

    IPC: A61F2/06 ,  A61L27/18 ,  A61L27/28 ,  A61L27/54 ,  A61L27/50 ,  A61L27/58 ,  A61L27/56

    CPC classification number: A61F2/06 ,  A61F2/062 ,  A61F2/064 ,  A61F2210/0004 ,  A61F2250/0019 ,  A61F2250/003 ,  A61F2250/0067 ,  A61L27/18 ,  A61L27/28 ,  A61L27/50 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2300/42 ,  A61L2420/08 ,  A61L2430/36 ,  C08L67/04

    Abstract: In some aspects, a graft device can include a biodegradable inner layer, an outer layer, a first end portion, a second end portion, and a lumen therebetween. The biodegradable inner layer typically includes an inner surface and an outer surface. The outer layer typically includes a fiber matrix surrounding the outer surface of the inner layer. The graft device can include a reinforced end portion. At least 10% or at least 50% of the graft device can remain after 90 days of implantation. In some cases, at least 10% or at least 50% of the graft device can remain after 180 days of implantation. The graft device can include a kink-resisting element. The graft device can include at least one layer with a dynamic compliance less than or equal to at least one of: 20%/100 mmHg or 5%/100 mmHg.

    Abstract translation: 在一些方面，移植装置可以包括可生物降解的内层，外层，第一端部，第二端部和其间的内腔。 可生物降解内层通常包括内表面和外表面。 外层通常包括围绕内层的外表面的纤维基质。 移植装置可以包括加强的端部。 移植装置的至少10％或至少50％可以在植入90天后保留。 在一些情况下，移植装置的至少10％或至少50％可以在植入180天后保留。 移植装置可以包括抗皱元件。 移植装置可包括至少一层具有小于或等于20％/ 100mmHg或5％/ 100mmHg中至少之一的动态顺应性的层。

    MULTIPLE LAYER VASCULAR GRAFT
    5.
    发明申请
    MULTIPLE LAYER VASCULAR GRAFT 有权

    公开(公告)号：US20210196445A1

    公开(公告)日：2021-07-01

    申请号：US17058776

    申请日：2019-06-07

    Applicant: NEOGRAFT TECHNOLOGIES, INC.

    Inventor： Mohammed El-Kurdi ,  Ayotte Ryan ,  Anh Thi Dinh ,  Kevin Farrell ,  Jon McGrath

    IPC: A61F2/06

    Abstract: Provided herein our graft devices for a patient comprising one or more layers, such as an inner layer and an outer layer. The inner layer comprises a first porous arrangement of fibers defining a first tube comprising an inner wall and an outer wall. The outer layer comprises a second porous arrangement of fibers defining a second tube comprising an inner wall and an outer wall. The second tube surrounds the first tube. A plurality of macropores extend through at least the inner and outer wall of the first tube. The inner and/or the outer layer can comprise a biofragmentable material configured to mechanically fracture into one or more fragments over time. Methods of creating graft devices are also disclosed.

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