公开(公告)号：US20210016496A1

公开(公告)日：2021-01-21

申请号：US16975458

申请日：2019-03-08

Applicant: NORTHWESTERN UNIVERSITY

Inventor： Xiangfan CHEN ,  Wenzhong LIU ,  Hao F. ZHANG ,  Cheng SUN

IPC: B29C64/129 ,  B33Y10/00

Abstract: In an aspect, a method for additive manufacture of a three-dimensional object based on a computational model comprises steps of: grayscale photohardening a precursor material to form a portion of the object; and applying a hardened meniscus coating at a feature of the object; wherein the three-dimensional object is formed via at least the combination of the steps of gray scale photohardening and applying the meniscus coating. In some embodiments, the grayscale photohardening step is a grayscale photopolymerization step. In some embodiments, the applying a hardened meniscus coating step is a meniscus equilibrium post-curing step.

公开(公告)号：US20180242844A1

公开(公告)日：2018-08-30

申请号：US15751107

申请日：2016-08-05

Applicant: Northwestern University

Inventor： Wenzhong LIU ,  Hao F. ZHANG ,  Kieren J. PATEL

IPC: A61B3/12 ,  A61B3/10 ,  A61B5/1455 ,  A61B3/00 ,  G06T7/00 ,  G16H40/63

CPC classification number: A61B3/1233 ,  A61B3/0025 ,  A61B3/102 ,  A61B5/0066 ,  A61B5/0261 ,  A61B5/14555 ,  A61B5/489 ,  A61B2576/02 ,  G06T7/0012 ,  G06T2207/10101 ,  G06T2207/30041 ,  G06T2207/30104 ,  G16H40/63

Abstract: The present disclosure provides systems and methods for objective focal length free measurements of fluid flow using OCT. In certain disclosed examples, fOCT data is acquired and optical information is extracted from fOCT scans to quantitatively determine a flow rate of fluid in the target. Determinations of flow rate can enable determination of a change in rate of an analyte over time. The current methods and systems of the disclosure can be used in assessing metabolism of a tissue, where oxygen is the analyte detected, or other functional states, and, more generally, be used for the diagnosis, monitoring and treatment of disease.