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公开(公告)号：US20100114235A1
公开(公告)日：2010-05-06
申请号：US12263337
申请日：2008-10-31
申请人： Naixiong Jiang , Gene A. Bornzin , Joseph Beauvais
发明人： Naixiong Jiang , Gene A. Bornzin , Joseph Beauvais
CPC分类号： A61N1/378 , A61N1/3956 , A61N1/3981 , H01M6/16 , H01M6/5033 , H01M10/0525 , H01M10/425 , H01M10/44 , H01M16/00 , H02J7/0054
摘要： A system and method for powering an implantable cardiac therapy device (ICTD) uses a hybrid battery system. In an embodiment, the hybrid battery system includes of a first type of power cell and a second type of power cell. The first power cell is configured to power low voltage, low current background operations of the ICTD. The second power cell is configured to power high voltage, high current cardiac shocking. The second power cell is further configured to be charged by the first power cell via a continuous, non-regulated charging process, thereby reducing the complexity of the charging circuitry. The system is further configured so that when cardiac shocking is in progress, only the secondary power cell powers the shocking capacitor(s) of the ICTD, and the first power cell is electrically isolated from the shocking capacitor(s). This configuration contributes to longer battery life of the hybrid battery system.
摘要翻译： 用于为植入式心脏治疗装置（ICTD）供电的系统和方法使用混合电池系统。 在一个实施例中，混合电池系统包括第一类型的功率单元和第二类型的功率单元。 第一个功率单元被配置为为ICTD的低电压，低电流背景操作供电。 第二个功率单元被配置为对高电压，高电流的心脏震荡进行供电。 第二功率单元还被配置为经由连续的非调节充电过程由第一功率单元充电，从而降低充电电路的复杂性。 该系统被进一步配置，使得当正在进行心脏震动时，只有次级电力单元为ICTD的冲击电容器供电，并且第一功率单元与冲击电容器电隔离。 该配置有助于混合电池系统的更长的电池寿命。
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公开(公告)号：US20110202105A1
公开(公告)日：2011-08-18
申请号：US13018140
申请日：2011-01-31
申请人： Naixiong Jiang , Gene A. Bornzin , John W. Poore , Sheldon Williams , Weiqun Yang , Taraneh Ghaffari Farazi
发明人： Naixiong Jiang , Gene A. Bornzin , John W. Poore , Sheldon Williams , Weiqun Yang , Taraneh Ghaffari Farazi
CPC分类号： A61N1/378 , H01M2/0275 , H01M2/1066 , H01M2/1653 , H01M2/18 , H01M2/361 , H01M4/12 , H01M4/366 , H01M4/48
摘要： A bioelectric battery may be used to power implantable devices. The bioelectric battery may have an anode electrode and a cathode electrode separated by an insulating member comprising a tube having a first end and a second end, wherein said anode is inserted into said first end of said tube and said cathode surrounds said tube such that the tube provides a support for the cathode electrode. The bioelectric battery may also have a membrane surrounding the cathode to reduce tissue encapsulation. Alternatively, an anode electrode, a cathode electrode surrounding the cathode electrode, a permeable membrane surrounding the cathode electrode. An electrolyte is disposed within the permeable membrane and a mesh surrounds the permeable membrane. In an alternative embodiment, a pacemaker housing acts as a cathode electrode for a bioelectric battery and an anode electrode is attached to the housing with an insulative adhesive.
摘要翻译： 生物电池可用于为可植入装置供电。 生物电池可以具有由包括具有第一端和第二端的管的绝缘构件分开的阳极电极和阴极电极，其中所述阳极插入所述管的所述第一端，所述阴极围绕所述管，使得 管为阴极提供支撑。 生物电池还可以具有围绕阴极的膜以减少组织包封。 或者，阳极电极，围绕阴极电极的阴极电极，围绕阴极电极的可渗透膜。 电解质设置在可渗透膜内，并且网围绕可渗透膜。 在替代实施例中，起搏器壳体用作生物电池的阴极电极，并且阳极通过绝缘粘合剂附接到壳体。
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3.发明申请HYBRID BATTERY SYSTEM WITH BIOELECTRIC CELL FOR IMPLANTABLE CARDIAC THERAPY DEVICE 审中-公开具有用于可植入心脏治疗装置的生物电池的混合电池系统公开(公告)号：US20100114236A1
公开(公告)日：2010-05-06
申请号：US12263348
申请日：2008-10-31
申请人： Naixiong Jiang , Gene A. Bornzin , John W. Poore
发明人： Naixiong Jiang , Gene A. Bornzin , John W. Poore
CPC分类号： A61N1/378 , A61N1/3956 , A61N1/3981 , H01M8/16 , H01M10/0525 , H01M10/425 , H01M10/44 , H01M16/006 , H02J7/0054 , H02J7/0063 , Y02E60/527
摘要： A system and method for powering an implantable cardiac therapy device (ICTD) via a hybrid battery system. The hybrid battery is comprised of a low voltage and low current bioelectric cell, a high voltage and high current rechargeable cell, and a charging means. Via the charging means, the bioelectric cell maintains the rechargeable cell at or near full power. The rechargeable cell is configured to power some or all operations of the ICTD. Some ICTD operations may be powered directly by the bioelectric cell. The rechargeable cell is further configured to be charged via a continuous charging process, reducing the complexity of the charging circuitry. In an embodiment, at least the bioelectric cell is external to the ICTD, enabling easy replacement of this power source. In an embodiment, a consumable anode of the bioelectric cell is external to the ICTD, enabling replacement of the power source by replacing only the anode.
摘要翻译： 通过混合电池系统为植入式心脏治疗装置（ICTD）供电的系统和方法。 混合电池包括低电压和低电流生物电池，高电压和高电流可再充电电池以及充电装置。 通过充电装置，生物电池将可再充电电池维持在或接近全功率。 可充电电池被配置为为ICTD的一些或所有操作供电。 一些ICTD操作可以由生物电池直接供电。 可再充电电池还被配置为经由连续充电过程进行充电，从而降低充电电路的复杂性。 在一个实施例中，至少生物电池在ICTD的外部，使得能够容易地更换该电源。 在一个实施例中，生物电池的消耗性阳极在ICTD的外部，能够通过仅替换阳极来替换电源。
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公开(公告)号：US08709631B1
公开(公告)日：2014-04-29
申请号：US11737307
申请日：2007-04-19
申请人： Naixiong Jiang , Gene A. Bornzin , John W. Poore , Sheldon Williams , Weiqun Yang , Taraneh Ghaffari Farazi
发明人： Naixiong Jiang , Gene A. Bornzin , John W. Poore , Sheldon Williams , Weiqun Yang , Taraneh Ghaffari Farazi
摘要： A bioelectric battery may be used to power implantable devices. The bioelectric battery may have an anode electrode and a cathode electrode separated by an insulating member comprising a tube having a first end and a second end, wherein said anode is inserted into said first end of said tube and said cathode surrounds said tube such that the tube provides a support for the cathode electrode. The bioelectric battery may also have a membrane surrounding the cathode to reduce tissue encapsulation. Alternatively, an anode electrode, a cathode electrode surrounding the cathode electrode, a permeable membrane surrounding the cathode electrode. An electrolyte is disposed within the permeable membrane and a mesh surrounds the permeable membrane. In an alternative embodiment, a pacemaker housing acts as a cathode electrode for a bioelectric battery and an anode electrode is attached to the housing with an insulative adhesive.
摘要翻译： 生物电池可用于为可植入装置供电。 生物电池可以具有由包括具有第一端和第二端的管的绝缘构件分开的阳极电极和阴极电极，其中所述阳极插入所述管的所述第一端，所述阴极围绕所述管，使得 管为阴极提供支撑。 生物电池还可以具有围绕阴极的膜以减少组织包封。 或者，阳极电极，围绕阴极电极的阴极电极，围绕阴极电极的可渗透膜。 电解质设置在可渗透膜内，并且网围绕可渗透膜。 在替代实施例中，起搏器壳体用作生物电池的阴极电极，并且阳极通过绝缘粘合剂附接到壳体。
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公开(公告)号：US08574737B2
公开(公告)日：2013-11-05
申请号：US13018140
申请日：2011-01-31
申请人： Naixiong Jiang , Gene A. Bornzin , John W. Poore , Sheldon Williams , Weiqun Yang , Taraneh Ghaffari Farazi
发明人： Naixiong Jiang , Gene A. Bornzin , John W. Poore , Sheldon Williams , Weiqun Yang , Taraneh Ghaffari Farazi
CPC分类号： A61N1/378 , H01M2/0275 , H01M2/1066 , H01M2/1653 , H01M2/18 , H01M2/361 , H01M4/12 , H01M4/366 , H01M4/48
摘要： A bioelectric battery may be used to power implantable devices. The bioelectric battery may have an anode electrode and a cathode electrode separated by an insulating member comprising a tube having a first end and a second end, wherein said anode is inserted into said first end of said tube and said cathode surrounds said tube such that the tube provides a support for the cathode electrode. The bioelectric battery may also have a membrane surrounding the cathode to reduce tissue encapsulation. Alternatively, an anode electrode, a cathode electrode surrounding the cathode electrode, a permeable membrane surrounding the cathode electrode. An electrolyte is disposed within the permeable membrane and a mesh surrounds the permeable membrane. In an alternative embodiment, a pacemaker housing acts as a cathode electrode for a bioelectric battery and an anode electrode is attached to the housing with an insulative adhesive.
摘要翻译： 生物电池可用于为可植入装置供电。 生物电池可以具有由包括具有第一端和第二端的管的绝缘构件分开的阳极电极和阴极电极，其中所述阳极插入所述管的所述第一端，所述阴极围绕所述管，使得 管为阴极提供支撑。 生物电池还可以具有围绕阴极的膜以减少组织包封。 或者，阳极电极，围绕阴极电极的阴极电极，围绕阴极电极的可渗透膜。 电解质设置在可渗透膜内，并且网围绕可渗透膜。 在替代实施例中，起搏器壳体用作生物电池的阴极电极，并且阳极通过绝缘粘合剂附接到壳体。
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6.发明授权Multi-piece dual-chamber leadless intra-cardiac medical device and method of implanting same 有权多片双室无引线心脏内心脏医疗器械及其植入方法公开(公告)号：US09017341B2
公开(公告)日：2015-04-28
申请号：US13352005
申请日：2012-01-17
申请人： Gene A. Bornzin , John W. Poore , Zoltan Somogyi , Xiaoyi Min
发明人： Gene A. Bornzin , John W. Poore , Zoltan Somogyi , Xiaoyi Min
CPC分类号： A61N1/059 , A61N1/0573 , A61N1/36521 , A61N1/37288 , A61N1/3756
摘要： A leadless intra-cardiac medical device (LIMD) includes an electrode assembly configured to be anchored within a first wall portion of a first chamber of a heart. The electrode assembly includes an electrode main body having a first securing helix, an electrode wire segment extending from the body, and a first segment-terminating contact positioned on the electrode wire segment. The device further includes a housing assembly configured to be anchored within a second wall portion of a second chamber of the heart. The housing assembly includes a body having a second securing helix, a housing wire segment extending from the body, and a second segment-terminating contact positioned on the housing wire segment. The device also includes a connector block that electrically connects the electrode wire segment to the housing wire segment by retaining the first and second segment-terminating contacts.
摘要翻译： 无引线心脏内心脏医疗装置（LIMD）包括被配置为锚定在心脏的第一腔室的第一壁部分内的电极组件。 电极组件包括具有第一固定螺旋线的电极主体，从主体延伸的电极线段和位于电极线段上的第一段终止触点。 该装置还包括壳体组件，其构造成锚固在心脏的第二腔室的第二壁部分内。 壳体组件包括具有第二固定螺旋的主体，从主体延伸的壳体线段和位于壳体线段上的第二段终止触点。 该装置还包括连接器块，其通过保持第一和第二段终止触点将电极线段电连接到壳体线段。
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7.发明授权公开(公告)号：US09008777B2
公开(公告)日：2015-04-14
申请号：US13529226
申请日：2012-06-21
申请人： Ali Dianaty , Gabriel A. Mouchawar , Gene A. Bornzin , John W. Poore , Xiaoyi Min , Zoltan Somogyi , Richard Williamson
发明人： Ali Dianaty , Gabriel A. Mouchawar , Gene A. Bornzin , John W. Poore , Xiaoyi Min , Zoltan Somogyi , Richard Williamson
CPC分类号： A61N1/3756 , A61B5/042 , A61N1/362 , A61N1/368 , Y10T29/49002
摘要： A leadless implantable medical device (LIMD) includes a housing formed from a battery and an end cap. A proximal end of the end cap forms an LIMD proximal end and a distal end of the battery case forms an LIMD distal end. A non-conductive coupler mechanically secures a terminal end of the battery case to a mating end of the end cap, while maintaining the battery case and end cap electrically separated. A first electrode projects from the proximal end of the end cap. An intra-cardiac (IC) device extension projects from the distal end of the battery case. The extension includes a second electrode that is electrically connected to the battery case. The second electrode is located remote from the LIMD distal end. An electronics module is located within an internal cavity of the end cap and communicates with the first and second electrodes.
摘要翻译： 无引线植入式医疗装置（LIMD）包括由电池和端盖形成的壳体。 端盖的近端形成LIMD近端，并且电池壳体的远端形成LIMD远端。 非导电耦合器将电池壳体的终端机械地固定到端盖的配合端，同时保持电池壳体和端盖电气分离。 第一电极从端盖的近端突出。 心脏内（IC）装置延伸部从电池盒的远端伸出。 该延伸部包括电连接到电池壳体的第二电极。 第二电极远离LIMD远端。 电子模块位于端盖的内部空腔内并与第一和第二电极连通。
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公开(公告)号：US08731665B1
公开(公告)日：2014-05-20
申请号：US11923286
申请日：2007-10-24
申请人： Xiaoyi Min , Laleh Jalali , Steve Koh , Gene A. Bornzin , Euljoon Park
发明人： Xiaoyi Min , Laleh Jalali , Steve Koh , Gene A. Bornzin , Euljoon Park
IPC分类号： A61N1/00
CPC分类号： A61N1/365 , A61N1/36535
摘要： Systems and methods are provided for detecting the orientation and/or movement of a patient having an implantable cardiac stimulation device and evaluating whether a change in the patient's cardiac activity can be at least in part due to a change in the patient's orientation. In one particular embodiment, signals from an orientation sensor and/or a pressure sensor are evaluated to determine static positional orientation of the patient and determine based on the static orientation whether the patient's cardiac activity is abnormal.
摘要翻译： 提供了用于检测具有可植入心脏刺激装置的患者的取向和/或运动的系统和方法，并且评估患者的心脏活动的变化是否可以至少部分地由于患者取向的改变而变化。 在一个特定实施例中，评估来自定向传感器和/或压力传感器的信号以确定患者的静态位置取向，并且基于静态取向来确定患者的心脏活动是否异常。
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9.发明授权Single-chamber leadless intra-cardiac medical device with dual-chamber functionality and shaped stabilization intra-cardiac extension 有权单室无引线心脏内心脏医疗器械，具有双室功能和形状稳定心脏扩张公开(公告)号：US08700181B2
公开(公告)日：2014-04-15
申请号：US13352101
申请日：2012-01-17
申请人： Gene A. Bornzin , Xiaoyi Min , John W. Poore , Zoltan Somogyi , Didier Theret
发明人： Gene A. Bornzin , Xiaoyi Min , John W. Poore , Zoltan Somogyi , Didier Theret
IPC分类号： A61N1/362
CPC分类号： A61N1/059 , A61N1/0573 , A61N1/3684 , A61N1/3756
摘要： A leadless intra-cardiac medical device (LIMD) configured to be implanted entirely within a heart of a patient includes a housing configured to be securely attached to an interior wall portion of a chamber of the heart, and a stabilizing intra-cardiac (IC) device extension connected to the housing. The stabilizing IC device extension may include a stabilizer arm, and/or an appendage arm, or an elongated body or a loop member configured to be passively secured within the heart.
摘要翻译： 被配置为完全植入患者心脏的无引线心脏内心脏医疗装置（LIMD）包括被构造成可靠地附接到心脏室的内壁部分的壳体，以及稳定心脏内（IC） 设备扩展连接到外壳。 稳定IC装置延伸部可以包括稳定器臂和/或附肢臂，或者被配置为被动地固定在心脏内的细长主体或环形构件。
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10.发明授权Dual-chamber leadless intra-cardiac medical device with intra-cardiac extension 有权具有心脏扩张的双室无引导心脏内心脏医疗器械公开(公告)号：US08634912B2
公开(公告)日：2014-01-21
申请号：US13352136
申请日：2012-01-17
申请人： Gene A. Bornzin , Gabriel A. Mouchawar , Xiaoyi Min , John W. Poore , Edward Karst , Richard Samade , Zoltan Somogyi , Didier Theret
发明人： Gene A. Bornzin , Gabriel A. Mouchawar , Xiaoyi Min , John W. Poore , Edward Karst , Richard Samade , Zoltan Somogyi , Didier Theret
IPC分类号： A61N1/362
CPC分类号： A61N1/056 , A61N1/057 , A61N1/0573 , A61N1/3622 , A61N1/368 , A61N1/3684 , A61N1/3688 , A61N1/3756
摘要： A leadless intra-cardiac medical device includes a housing that is configured to be implanted entirely within a single local chamber of the heart. A first electrode is provided on the housing at a first position such that when the housing is implanted in the local chamber, the first electrode engages the local wall tissue at a local activation site within the conduction network of the local chamber. An intra-cardiac extension is coupled to the housing and configured to extend from the local chamber into an adjacent chamber of the heart. A stabilization arm of the intra-cardiac extension engages the adjacent chamber. A second electrode on the intra-cardiac extension engages distal wall tissue at a distal activation site within the conduction network of the adjacent chamber.
摘要翻译： 无引线心脏内心脏医疗设备包括被配置为完全植入心脏的单个局部腔室内的壳体。 第一电极在第一位置处设置在壳体上，使得当壳体被植入局部腔室时，第一电极在局部腔室的传导网络内的局部激活位置接合局部壁组织。 心脏内延伸部分耦合到壳体并且构造成从局部腔室延伸到心脏的相邻室中。 心脏内延伸部的稳定臂与相邻的腔室相接合。 心脏延伸部分上的第二个电极与相邻腔室的传导网络内的远端活化位点处的远端壁组织接合。
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