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公开(公告)号:US20080302393A1
公开(公告)日:2008-12-11
申请号:US12118367
申请日:2008-05-09
申请人: Nasser Jafari , Lawrence Blecka , Chris Tsai
发明人: Nasser Jafari , Lawrence Blecka , Chris Tsai
CPC分类号: B08B9/00 , B01L99/00 , B08B3/022 , G01N35/1004 , Y10S134/902
摘要: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.
摘要翻译: 提供了包括洗涤环组件的装置和方法,用于从用于传送流体的探针的外部或内部除去过量的流体或固体,例如在自动测定装置中。 通常,使用探针抽吸和分配样品流体材料,例如全血或试剂。 本文提供的装置和方法可用于从探针的外部或内部去除多余的流体,以防止样品或试剂之间的滴落和交叉污染。 还可以想到,利用本文提供的装置和方法,当探针运动,抽吸样品和/或分配样品时,可以同时进行洗涤和/或干燥。
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公开(公告)号:US08136539B2
公开(公告)日:2012-03-20
申请号:US12118367
申请日:2008-05-09
申请人: Nasser Jafari , Lawrence Blecka , Chris Tsai
发明人: Nasser Jafari , Lawrence Blecka , Chris Tsai
CPC分类号: B08B9/00 , B01L99/00 , B08B3/022 , G01N35/1004 , Y10S134/902
摘要: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.
摘要翻译: 提供了包括洗涤环组件的装置和方法,用于从用于传送流体的探针的外部或内部除去过量的流体或固体,例如在自动测定装置中。 通常,使用探针抽吸和分配样品流体材料,例如全血或试剂。 本文提供的装置和方法可用于从探针的外部或内部去除多余的流体,以防止样品或试剂之间的滴落和交叉污染。 还可以想到,利用本文提供的装置和方法,当探针运动,抽吸样品和/或分配样品时,可以同时进行洗涤和/或干燥。
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公开(公告)号:US20110262896A1
公开(公告)日:2011-10-27
申请号:US13094743
申请日:2011-04-26
申请人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken J. Lafredo
发明人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken J. Lafredo
CPC分类号: B01L9/00 , G01N15/14 , G01N15/1459 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N2035/00356 , Y10T436/11 , Y10T436/113332 , Y10T436/143333 , Y10T436/25 , Y10T436/2575
摘要: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
摘要翻译: 本发明提供了用于同时检测样品中多种分析物的系统和方法。 检测系统包括容纳可旋转地联接到其上的试剂转盘的壳体。 还包括在壳体中的是可旋转地联接到其上的孵化器转盘。 壳体还包括与培养转盘相关联的磁性材料,用于帮助从试剂和洗涤溶液中分离珠子。 与壳体相关联的机器人被配置为操纵试剂转盘或培养箱转盘中的至少一个并在其间转移材料。 反应容器保持样品和反应容器处理器移动反应容器。 样品分析由至少一个基于激光的检测器确定。
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公开(公告)号:US07955555B2
公开(公告)日:2011-06-07
申请号:US11784596
申请日:2007-04-06
申请人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken J. Lafredo
发明人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken J. Lafredo
IPC分类号: G01N33/48
CPC分类号: B01L9/00 , G01N15/14 , G01N15/1459 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N2035/00356 , Y10T436/11 , Y10T436/113332 , Y10T436/143333 , Y10T436/25 , Y10T436/2575
摘要: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
摘要翻译: 本发明提供了用于同时检测样品中多种分析物的系统和方法。 检测系统包括容纳可旋转地联接到其上的试剂转盘的壳体。 还包括在壳体中的是可旋转地联接到其上的孵化器转盘。 壳体还包括与培养转盘相关联的磁性材料,用于帮助从试剂和洗涤溶液中分离珠子。 与壳体相关联的机器人被配置为操纵试剂转盘或培养箱转盘中的至少一个并在其间转移材料。 反应容器保持样品和反应容器处理器移动反应容器。 样品分析由至少一个基于激光的检测器确定。
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公开(公告)号:US08449687B2
公开(公告)日:2013-05-28
申请号:US13372300
申请日:2012-02-13
申请人: Nasser Jafari , Lawrence Blecka , Chris Tsai
发明人: Nasser Jafari , Lawrence Blecka , Chris Tsai
CPC分类号: B08B9/00 , B01L99/00 , B08B3/022 , G01N35/1004 , Y10S134/902
摘要: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.
摘要翻译: 提供了包括洗涤环组件在内的装置和方法,用于从用于传送流体的探针的外部或内部除去过量的流体或固体,例如在自动测定装置中。 通常,使用探针抽吸和分配样品流体材料,例如全血或试剂。 本文提供的装置和方法可用于从探针的外部或内部去除多余的流体,以防止样品或试剂之间的滴落和交叉污染。 还可以想到,利用本文提供的装置和方法,当探针运动,抽吸样品和/或分配样品时,可以同时进行洗涤和/或干燥。
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公开(公告)号:US08357537B2
公开(公告)日:2013-01-22
申请号:US13094743
申请日:2011-04-26
申请人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken J. Lafredo
发明人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken J. Lafredo
CPC分类号: B01L9/00 , G01N15/14 , G01N15/1459 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N2035/00356 , Y10T436/11 , Y10T436/113332 , Y10T436/143333 , Y10T436/25 , Y10T436/2575
摘要: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
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公开(公告)号:US20120138099A1
公开(公告)日:2012-06-07
申请号:US13372300
申请日:2012-02-13
申请人: Nasser Jafari , Lawrence Blecka , Chris Tsai
发明人: Nasser Jafari , Lawrence Blecka , Chris Tsai
CPC分类号: B08B9/00 , B01L99/00 , B08B3/022 , G01N35/1004 , Y10S134/902
摘要: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.
摘要翻译: 提供了包括洗涤环组件的装置和方法,用于从用于传送流体的探针的外部或内部除去过量的流体或固体,例如在自动测定装置中。 通常,使用探针抽吸和分配样品流体材料,例如全血或试剂。 本文提供的装置和方法可用于从探针的外部或内部去除多余的流体,以防止样品或试剂之间的滴落和交叉污染。 还可以想到,利用本文提供的装置和方法,当探针运动,抽吸样品和/或分配样品时,可以同时进行洗涤和/或干燥。
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公开(公告)号:US20070189925A1
公开(公告)日:2007-08-16
申请号:US11784596
申请日:2007-04-06
申请人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken Lafredo
发明人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken Lafredo
IPC分类号: G01N35/00
CPC分类号: B01L9/00 , G01N15/14 , G01N15/1459 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N2035/00356 , Y10T436/11 , Y10T436/113332 , Y10T436/143333 , Y10T436/25 , Y10T436/2575
摘要: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
摘要翻译: 本发明提供了用于同时检测样品中多种分析物的系统和方法。 检测系统包括容纳可旋转地联接到其上的试剂转盘的壳体。 还包括在壳体中的是可旋转地联接到其上的孵化器转盘。 壳体还包括与培养转盘相关联的磁性材料,用于帮助从试剂和洗涤溶液中分离珠子。 与壳体相关联的机器人被配置为操纵试剂转盘或培养箱转盘中的至少一个并在其间转移材料。 反应容器保持样品和反应容器处理器移动反应容器。 样品分析由至少一个基于激光的检测器确定。
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公开(公告)号:US07220385B2
公开(公告)日:2007-05-22
申请号:US10894824
申请日:2004-07-19
申请人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken Lafredo
发明人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken Lafredo
CPC分类号: B01L9/00 , G01N15/14 , G01N15/1459 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N2035/00356 , Y10T436/11 , Y10T436/113332 , Y10T436/143333 , Y10T436/25 , Y10T436/2575
摘要: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
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公开(公告)号:US20050123445A1
公开(公告)日:2005-06-09
申请号:US10894824
申请日:2004-07-19
申请人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken Lafredo
发明人: Lawrence Blecka , Larry Seamer , Sachi Rastogi , Chris Tsai , Nasser Jafari , Ken Lafredo
IPC分类号: G01N20060101 , G01N35/00 , G01N35/02
CPC分类号: B01L9/00 , G01N15/14 , G01N15/1459 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N2035/00356 , Y10T436/11 , Y10T436/113332 , Y10T436/143333 , Y10T436/25 , Y10T436/2575
摘要: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
摘要翻译: 本发明提供了用于同时检测样品中多种分析物的系统和方法。 检测系统包括容纳可旋转地联接到其上的试剂转盘的壳体。 还包括在壳体中的是可旋转地联接到其上的孵化器转盘。 壳体还包括与培养转盘相关联的磁性材料,用于帮助从试剂和洗涤溶液中分离珠子。 与壳体相关联的机器人被配置为操纵试剂转盘或培养箱转盘中的至少一个并在其间转移材料。 反应容器保持样品和反应容器处理器移动反应容器。 样品分析由至少一个基于激光的检测器确定。
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