-
公开(公告)号:US20070184554A1
公开(公告)日:2007-08-09
申请号:US11606896
申请日:2006-12-01
申请人: Nathan Teuscher , Lidia Demchyshyn , David Wells
发明人: Nathan Teuscher , Lidia Demchyshyn , David Wells
IPC分类号: G01N33/00
CPC分类号: A61K38/26 , G01N33/6812 , G01N2800/065 , G01N2800/52
摘要: The invention disclosed herein demonstrates that that the adaptive process in the intestine can be tracked using plasma citrulline. It further demonstrates that plasma citrulline is of clinical utility as a biomarker for improvements in intestinal function.
摘要翻译: 本文公开的发明证明可以使用血浆瓜氨酸来跟踪肠道中的适应过程。 进一步证明血浆瓜氨酸作为改善肠功能的生物标志物具有临床效用。
-
2.
公开(公告)号:US20120295298A1
公开(公告)日:2012-11-22
申请号:US13565618
申请日:2012-08-02
申请人: Lidia Demchyshyn , Hong Wang
发明人: Lidia Demchyshyn , Hong Wang
IPC分类号: C12Q1/02
CPC分类号: G01N33/5082 , G01N33/5088 , G01N33/74 , G01N2333/605 , G01N2333/726 , G01N2500/04 , G01N2500/10
摘要: Disclosed herein is a method for measuring the contractility of intestinal tissue upon treatment with GLP-2 or a GLP-2 ligand. Also disclosed is an assay which directly measures the activity of GLP-2 or GLP-2 ligands ex vivo and permits the screening of putative GLP-2 ligands in native tissue.
摘要翻译: 本文公开了一种用于在用GLP-2或GLP-2配体处理时测量肠组织的收缩性的方法。 还公开了一种直接测量GLP-2或GLP-2配体活性的测定法,并允许在天然组织中筛选推定的GLP-2配体。
-
3.
公开(公告)号:US07977061B2
公开(公告)日:2011-07-12
申请号:US12358123
申请日:2009-01-22
申请人: Lidia Demchyshyn , Hong Wang
发明人: Lidia Demchyshyn , Hong Wang
IPC分类号: G01N33/567
CPC分类号: G01N33/5082 , G01N33/5088 , G01N33/74 , G01N2333/605 , G01N2333/726 , G01N2500/04 , G01N2500/10
摘要: Disclosed herein is a method for measuring the contractility of intestinal tissue upon treatment with GLP-2 or a GLP-2 ligand. Also disclosed is an assay which directly measures the activity of GLP-2 or GLP-2 ligands ex vivo and permits the screening of putative GLP-2 ligands in native tissue.
摘要翻译: 本文公开了一种用于在用GLP-2或GLP-2配体处理时测量肠组织的收缩性的方法。 还公开了一种直接测量GLP-2或GLP-2配体活性的测定法,并允许在天然组织中筛选推定的GLP-2配体。
-
公开(公告)号:US20100003703A1
公开(公告)日:2010-01-07
申请号:US12358123
申请日:2009-01-22
申请人: Lidia Demchyshyn , Hong Wang
发明人: Lidia Demchyshyn , Hong Wang
IPC分类号: G01N33/567
CPC分类号: G01N33/5082 , G01N33/5088 , G01N33/74 , G01N2333/605 , G01N2333/726 , G01N2500/04 , G01N2500/10
摘要: Disclosed herein is a method for measuring the contractility of intestinal tissue upon treatment with GLP-2 or a GLP-2 ligand. Also disclosed is an assay which directly measures the activity of GLP-2 or GLP-2 ligands ex vivo and permits the screening of putative GLP-2 ligands in native tissue.
摘要翻译: 本文公开了一种用于在用GLP-2或GLP-2配体处理时测量肠组织的收缩性的方法。 还公开了一种直接测量GLP-2或GLP-2配体活性的测定法,并允许在天然组织中筛选推定的GLP-2配体。
-
公开(公告)号:US20070154959A1
公开(公告)日:2007-07-05
申请号:US11607030
申请日:2006-12-01
申请人: Lidia Demchyshyn , Hong Wang
发明人: Lidia Demchyshyn , Hong Wang
IPC分类号: G01N33/567 , G01N33/53
CPC分类号: G01N33/5082 , G01N33/5088 , G01N33/74 , G01N2333/605 , G01N2333/726 , G01N2500/04 , G01N2500/10
摘要: Disclosed herein is a method for measuring the contractility of intestinal tissue upon treatment with GLP-2 or a GLP-2 ligand. Also disclosed is an assay which directly measures the activity of GLP-2 or GLP-2 ligands ex vivo and permits the screening of putative GLP-2 ligands in native tissue.
摘要翻译: 本文公开了一种用于在用GLP-2或GLP-2配体处理时测量肠组织的收缩性的方法。 还公开了一种直接测量GLP-2或GLP-2配体活性的测定法,并允许在天然组织中筛选推定的GLP-2配体。
-
6.
公开(公告)号:US20120003681A1
公开(公告)日:2012-01-05
申请号:US13154071
申请日:2011-06-06
申请人: Lidia Demchyshyn , Hong Wang
发明人: Lidia Demchyshyn , Hong Wang
IPC分类号: C12Q1/02
CPC分类号: G01N33/5082 , G01N33/5088 , G01N33/74 , G01N2333/605 , G01N2333/726 , G01N2500/04 , G01N2500/10
摘要: Disclosed herein is a method for measuring the contractility of intestinal tissue upon treatment with GLP-2 or a GLP-2 ligand. Also disclosed is an assay which directly measures the activity of GLP-2 or GLP-2 ligands ex vivo and permits the screening of putative GLP-2 ligands in native tissue.
摘要翻译: 本文公开了一种用于在用GLP-2或GLP-2配体处理时测量肠组织的收缩性的方法。 还公开了一种直接测量GLP-2或GLP-2配体活性的测定法,并允许在天然组织中筛选推定的GLP-2配体。
-
公开(公告)号:US07498141B2
公开(公告)日:2009-03-03
申请号:US11607030
申请日:2006-12-01
申请人: Lidia Demchyshyn , Hong Wang
发明人: Lidia Demchyshyn , Hong Wang
IPC分类号: G01N33/567 , G01N33/53 , C12Q1/00
CPC分类号: G01N33/5082 , G01N33/5088 , G01N33/74 , G01N2333/605 , G01N2333/726 , G01N2500/04 , G01N2500/10
摘要: Disclosed herein is a method for measuring the contractility of intestinal tissue upon treatment with GLP-2 or a GLP-2 ligand. Also disclosed is an assay which directly measures the activity of GLP-2 or GLP-2 ligands ex vivo and permits the screening of putative GLP-2 ligands in native tissue.
摘要翻译: 本文公开了一种用于在用GLP-2或GLP-2配体处理时测量肠组织的收缩性的方法。 还公开了一种直接测量GLP-2或GLP-2配体活性的测定法,并允许在天然组织中筛选推定的GLP-2配体。
-
-
-
-
-
-