公开(公告)号：US20230090065A1

公开(公告)日：2023-03-23

申请号：US17800386

申请日：2021-03-05

Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

Inventor： Ryo TAMURA ,  Hanxiao XU ,  Koki KITAI ,  Kosuke MINAMI ,  Makito NAKATSU ,  Genki YOSHIKAWA ,  Kota SHIBA ,  Koji TSUDA

IPC: G01N33/00

Abstract: The present invention makes it possible to represent or synthesize any odor by separating the odor into a combination of a relatively small number of odors, similarly to separating a color into three primary colors. Since the “primary odors” corresponding to the primary colors have not yet been ascertained, the present invention provides a feasible method and apparatus in which, instead of presetting such fixed primary odors, the separation, synthesis, and the like can be performed by selecting a subset of odors from among a set consisting of a plurality of odors which subset or odors enables approximation of other odors as much as possible by mixture.

公开(公告)号：US20220260540A1

公开(公告)日：2022-08-18

申请号：US17627421

申请日：2020-06-17

Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

Inventor： Genki YOSHIKAWA ,  Takahiro NEMOTO ,  Masaaki MATOBA ,  Kosuke MINAMI

IPC: G01N33/00 ,  G01N1/38

Abstract: The present invention suppresses an adverse effect caused when an additional gas such as water vapor is mixed in a sample gas or the like that is subjected to gas measurement. In an embodiment of the present invention, in gas measurement for analyzing sensor output signals obtained by alternately supplying a sample gas and a reference gas to a sensor element while alternately switching between the sample gas and the reference gas, the sample gas and the reference gas pass through a humidity equilibration device partitioned by a water vapor permeable membrane, and then are supplied to the sensor element. As a result, since both gases have substantially the same value of humidity at the time of being supplied to the sensor element, influences of water vapor are substantially cancelled out in signals output from the sensor element by the alternate supply of the sample gas and the reference gas.

公开(公告)号：US20210215556A1

公开(公告)日：2021-07-15

申请号：US17267094

申请日：2019-08-28

Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

Inventor： Genki YOSHIKAWA ,  Takahiro NEMOTO ,  Makito NAKATSU ,  Naoto TAKEDA ,  Kota SHIBA ,  Kosuke MINAMI

IPC: G01L1/26 ,  G01L1/22 ,  B08B7/00

Abstract: A method for cleaning a receptor layer of a surface stress sensor according to an embodiment of the present invention includes, in a surface stress sensor that detects a change in surface stress of a thin film, the change being caused by a receptor layer disposed on a surface of the thin film, causing at least a part of a surface region of the thin film to generate heat or supplying heat to the receptor layer from the outside of the surface stress sensor. This makes it possible to easily perform efficient cleaning of a surface stress sensor such as a sensor that performs detection using a piezoresistor while avoiding structural complications as much as possible.

公开(公告)号：US20210199563A1

公开(公告)日：2021-07-01

申请号：US17057747

申请日：2019-06-04

Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

Inventor： Kosuke MINAMI ,  Gaku IMAMURA ,  Kota SHIBA ,  Genki YOSHIKAWA

IPC: G01N19/00 ,  G01N5/02

Abstract: In an analysis of a fluid component using a nanomechanical sensor covered with a receptor, the same receptor is caused to express different response characteristics. In a measuring system of analyzing a response when a sample gas and a purge gas are supplied to a nanomechanical sensor while switching the sample gas and the purge gas, a gas (external gas) different from both gases is mixed into a gas channel and supplied to the sensor for measurement. Since a response characteristic of a receptor is modulated by mixing of the external gas, the object described above is achieved.

公开(公告)号：US20230273183A1

公开(公告)日：2023-08-31

申请号：US18015792

申请日：2021-07-12

Applicant: National Institute for Materials Science

Inventor： Ryoh NAKAKUBO ,  Mitsuyoshi ISHIDA ,  Genki YOSHIKAWA ,  Kosuke MINAMI ,  Gaku IMAMURA ,  Hideki MATSUZAKA ,  Takahiro NEMOTO

IPC: G01N33/487

CPC classification number: G01N33/487

Abstract: An object of the present invention is to make it possible to easily determine a presence or absence of ketosis and/or the possibility of ketosis in an animal on site or the like. Another object of the present invention is to provide an apparatus for performing the determination. A method for determining ketosis according to one embodiment of the present invention includes providing gas detection means with a gas generated from a body fluid collected from an animal (except for humans), and determining ketosis of the animal based on a composition of the gas generated from the body fluid using a response of the gas detection means to the gas generated from the body fluid.

公开(公告)号：US20200249201A1

公开(公告)日：2020-08-06

申请号：US16613161

申请日：2018-05-21

Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

Inventor： Kota SHIBA ,  Kosuke MINAMI ,  Genki YOSHIKAWA

IPC: G01N29/02

Abstract: The present invention provides a nanomechanical sensor in which a negative influence of water in a sample on measurement is suppressed. In an embodiment of the present invention, as a receptor material of the nanomechanical sensor, a low-hygroscopic material such as polysulfone, polycaprolactone, poly(vinylidene fluoride), or poly(4-methylstyrene) is used. According to this embodiment, a negative influence, such as saturation of a receptor layer by water in the sample, or masking of an output signal based on trace components by an output signal based on water contained in the sample in a large amount, can be suppressed.

公开(公告)号：US20180003604A1

公开(公告)日：2018-01-04

申请号：US15543298

申请日：2015-08-31

Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

Inventor： Kota SHIBA ,  Genki YOSHIKAWA ,  Yusuke YAMAUCHI ,  Norihiro SUZUKI ,  Gaku IMAMURA ,  Kosuke MINAMI ,  Hamish Hei-Man YEUNG

IPC: G01N5/02 ,  G01N21/49 ,  G01N27/22

CPC classification number: G01N5/02 ,  B82Y15/00 ,  G01G3/13 ,  G01N21/49 ,  G01N27/227 ,  G01N29/022 ,  G01N29/036 ,  G01N2021/495 ,  G01N2291/014 ,  G01N2291/021 ,  G01N2291/022 ,  G01N2291/02433 ,  G01N2291/0256

Abstract: According to improvement of the receptor layer of various sensors of the type for detecting physical parameters (for example, a surface stress sensor, QCM, and SPR), all of high sensitivity, selectivity, and durability are achieved simultaneously. A porous material or a particulate material, e.g., nanoparticles, is used in place of a uniform membrane which has been conventionally used as a receptor layer. Accordingly, the sensitivity can be controlled by changing the membrane thickness of the receptor layer, the selectivity can be controlled by changing a surface modifying group to be fixed on the porous material or particulate material, and the durability can be controlled by changing the composition and surface properties of the porous material or particulate material.

公开(公告)号：US20230147626A1

公开(公告)日：2023-05-11

申请号：US17914956

申请日：2021-03-19

Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

Inventor： Ryo NAKAKUBO ,  Mitsuyoshi ISHIDA ,  Masanori TOHNO ,  Hisami KOBAYASHI ,  Genki YOSHIKAWA ,  Kosuke MINAMI ,  Gaku IMAMURA ,  Hideki MATSUZAKA ,  Takahiro NEMOTO

IPC: G01N33/00

CPC classification number: G01N33/0047

Abstract: An object of the present invention is to make it possible to easily evaluate silage fermentation quality on site or the like. In one embodiment of the present invention, a gas generated from silage is applied to a surface stress sensor, and the amount of either one of organic acids and nitrogen-containing compounds contained in the silage is determined. The surface stress sensor can detect trace components in a gas by a simple device configuration and in simple procedures. Therefore, by utilizing the fact that relationship between the content of these components and the fermentation quality is known, the evaluation of fermentation quality can be easily realized by the above measurement.

公开(公告)号：US20220291185A1

公开(公告)日：2022-09-15

申请号：US17619024

申请日：2020-05-08

Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

Inventor： Gaku IMAMURA ,  Kosuke MINAMI ,  Kota SHIBA ,  Genki YOSHIKAWA

IPC: G01N33/00 ,  G01N29/02 ,  G01L1/18 ,  G01N5/02 ,  C08F222/06

Abstract: An object of the present invention is to detect ammonia with high sensitivity and high selectivity using a nanomechanical sensor with a structure that is as simple as possible. A method for detecting ammonia according to an embodiment of the present invention comprises supplying a sample gas possibly containing ammonia to a nanomechanical sensor that detects a stress or a displacement using poly(methyl vinyl ether-alt-maleic anhydride) as a material of a receptor layer, and detecting presence or absence of ammonia or a content of ammonia in the sample gas based on an output signal from the nanomechanical sensor, in which the sample gas is a humidified sample gas with controlled relative humidity.

公开(公告)号：US20210396699A1

公开(公告)日：2021-12-23

申请号：US17289394

申请日：2019-11-13

Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

Inventor： Kosuke MINAMI ,  Genki YOSHIKAWA

IPC: G01N27/12 ,  G06N20/00

Abstract: The present invention provides a method for analyzing a liquid sample that solves a problem of a kinetically slow equilibrium at a liquid-solid interface, the problem occurring when liquid sample analysis is performed with a chemical sensor. In the method for analyzing a liquid sample according to an embodiment of the present invention, a component to be analyzed in a liquid sample is adsorbed on a receptor layer of a chemical sensor, one or more kinds of gases are then supplied to the chemical sensor, and a response thereof is measured. As a result, since a slow equilibrium at a liquid-solid interface is not used, a high-sensitivity measurement can be performed in a short time, and existing findings regarding analysis of gas samples on which much progress in research has been achieved can be used.