-
公开(公告)号：US09688638B2
公开(公告)日：2017-06-27
申请号：US15039686
申请日：2014-11-27
申请人： NEKTAR THERAPEUTICS (INDIA) PVT.LTD. , NEKTAR THERAPEUTICS (Incorporated under the Laws of Delaware and domiclled in the State of California)
IPC分类号： C07D221/22 , C07D221/26 , C07D513/08 , C07D401/12
CPC分类号： C07D221/26 , C07D401/12 , C07D513/08
摘要： Provided are compounds, including those of Formula I; and pharmaceutically acceptable salts and solvates thereof. The compounds described herein relate to and/or have application(s) in (among others) the fields of drug discovery, pharmacotherapy, physiology, organic chemistry and polymer chemistry.
-
公开(公告)号：US20170022167A1
公开(公告)日：2017-01-26
申请号：US15039686
申请日：2014-11-27
申请人： NEKTAR THERAPEUTICS (INDIA) PVT.LTD. , NEKTAR THERAPEUTICS (Incorporated Under the laws of Delaware and domiclled in the State of Ca.)
IPC分类号： C07D221/26 , C07D401/12 , C07D513/08
CPC分类号： C07D221/26 , C07D401/12 , C07D513/08
摘要： Provided are compounds, including those of Formula I; and pharmaceutically acceptable salts and solvates thereof. The compounds described herein relate to and/or have application(s) in (among others) the fields of drug discovery, pharmacotherapy, physiology, organic chemistry and polymer chemistry.
摘要翻译： 提供的化合物包括式I化合物; 及其药学上可接受的盐和溶剂化物。 本文所述的化合物涉及（和其中）药物发现，药物治疗，生理学，有机化学和聚合物化学领域中和/或具有应用。
-
公开(公告)号：US20240299561A1
公开(公告)日：2024-09-12
申请号：US18570610
申请日：2022-06-17
申请人： Nektar Therapeutics
发明人： Antoni Kozlowski , Neel K. Anand , Xiaoming Shen , Xiaobing Wang
IPC分类号： A61K47/60 , C08G65/333
CPC分类号： A61K47/60 , C08G65/3332
摘要： The instant disclosure provides (among other things) novel water-soluble polymer reagents capable of selective conjugation to histidine residues. e.g., in peptides and proteins, as well the resulting conjugates and related compositions. In addition, provided are methods of preparing the polymer reagents, as well as methods for conjugating the polymer reagents to active agents and other substances, pharmaceutical compositions, and methods for administering the conjugates.
-
4.发明申请公开(公告)号：US20190269652A1
公开(公告)日：2019-09-05
申请号：US16412096
申请日：2019-05-14
申请人： Nektar Therapeutics
IPC分类号： A61K31/4025 , C07D207/04 , C07D295/135 , C07D295/13 , C07D207/14 , C07D213/71 , C07D261/10 , C07D239/60 , C07D333/34 , C07D231/18 , C07D207/12
摘要： Compounds and pharmaceutically acceptable salts and solvates thereof are described. The compounds relate to and/or have application(s) in (among others) the fields of drug discovery, pharmacotherapy, physiology and organic chemistry.
-
公开(公告)号：US10081602B2
公开(公告)日：2018-09-25
申请号：US15603942
申请日：2017-05-24
申请人： Nektar Therapeutics
IPC分类号： C07D221/26 , C07D401/12 , C07D513/08
CPC分类号： C07D221/26 , C07D401/12 , C07D513/08
摘要： Provided are compounds, including those of Formula I; and pharmaceutically acceptable salts and solvates thereof. The compounds described herein relate to and/or have application(s) in (among others) the fields of drug discovery, pharmacotherapy, physiology, organic chemistry and polymer chemistry.
-
公开(公告)号：US20180185499A1
公开(公告)日：2018-07-05
申请号：US15908286
申请日：2018-02-28
申请人： Nektar Therapeutics
IPC分类号： A61K47/59 , C07C237/44 , A61K31/166 , C07C231/12
CPC分类号： A61K47/59 , A61K31/166 , A61K47/60 , C07C231/12 , C07C237/44
摘要： The invention relates to (among other things) oligomer-containing benzamide-based compound compounds. A compound of the invention exhibits one or more advantages over corresponding compounds lacking the oligomer.
-
公开(公告)号：US20210130467A1
公开(公告)日：2021-05-06
申请号：US16639520
申请日：2018-08-17
申请人： Nektar Therapeutics
发明人： Jonathan Zalevsky , Neel K. Anand , Haiying Cai , Bo-Liang Deng , Zhongxu Ren , Bhalchandra V. Joshi , Mary Tagliaferri , Werner Rubas , Saul Kivimae , Rhoneil L. Pena
摘要： Disclosed herein are methods in the field of cancer immunotherapy that involve the treatment of a subject having cancer by administering to the subject a toll-like receptor 7/8 (TLR7/8) agonist in combination with a long-acting IL-2Rβ-biased agonist and a programmed cell death protein 1 (PD-1)/programmed cell death protein ligand 1 (PD-L1) axis inhibitor, and related compositions, dosage forms, and kits.
-
公开(公告)号：US10434181B2
公开(公告)日：2019-10-08
申请号：US15908286
申请日：2018-02-28
申请人： Nektar Therapeutics
IPC分类号： C07C237/44 , A61K47/59 , A61K31/166 , C07C231/12 , A61K47/60
摘要： The invention relates to (among other things) oligomer-containing benzamide-based compound compounds. A compound of the invention exhibits one or more advantages over corresponding compounds lacking the oligomer.
-
公开(公告)号：US10189859B2
公开(公告)日：2019-01-29
申请号：US15106741
申请日：2014-12-19
申请人： Nektar Therapeutics
发明人： Pankaj Sharma , Vijay Kumar Khatri , Xuyuan Gu , Yuan Song , Michael Lixin Shen , Jennifer Riggs-Sauthier , Neel K. Anand , Antoni Kozlowski , Aleksandrs Odinecs , Timothy A. Riley , Zhongxu Ren , YongQi Mu , Xiaoming Shen , Xuejun Yuan , Natalia Aurrecoechea , Donogh John Roger O'Mahony , Bo-Liang Deng
IPC分类号： C07D253/075 , C07D403/04 , C07D401/04 , A61K31/53 , A61K31/496 , A61P25/02 , A61P25/18 , A61P33/06 , C07D498/04 , A61P25/28 , C07D401/12 , C07D403/12 , C07D405/12 , C07D471/10
摘要： The instant disclosure relates to (among other things) compounds that are derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine. The compounds provided possess unique effects and differences over other phenyltriazines known in the art.
-
公开(公告)号：US20180362468A1
公开(公告)日：2018-12-20
申请号：US16109456
申请日：2018-08-22
申请人： Nektar Therapeutics
IPC分类号： C07D221/26 , C07D401/12 , C07D513/08
摘要： Provided are compounds, including those of Formula I; and pharmaceutically acceptable salts and solvates thereof. The compounds described herein relate to and/or have application(s) in (among others) the fields of drug discovery, pharmacotherapy, physiology, organic chemistry and polymer chemistry.
-
-
-
-
-
-
-
-
-
搜索结果
35 条记录 (耗时 0.028 秒)
