公开(公告)号：US09388236B2

公开(公告)日：2016-07-12

申请号：US13870374

申请日：2013-04-25

Applicant: Nestec SA

Inventor： George Wells ,  Ebenezer Satyaraj

IPC: A61K39/395 ,  A61K39/00 ,  G01N33/53 ,  C07K16/18

CPC classification number: C07K16/18 ,  A61K2039/505 ,  A61K2039/54 ,  A61K2039/552 ,  C07K16/468 ,  C07K2317/76 ,  C07K2319/00

Abstract: Compositions suitable for reducing symptoms of an allergic response to environmental allergens comprising molecules that specifically inhibit the ability of the allergen to bind to mast cells in an animal predisposed to having an allergic response to the allergen and methods for reducing such symptoms comprising contacting a source of the environmental allergen with such compositions. Kits, packages, medicaments, and means of communicating about the compositions and methods are also provided.

公开(公告)号：US20160289312A1

公开(公告)日：2016-10-06

申请号：US15181813

申请日：2016-06-14

Applicant: Nestec SA

Inventor： George Wells ,  Ebenezer Satyaraj

IPC: C07K16/18 ,  C07K16/46

CPC classification number: C07K16/18 ,  A61K2039/505 ,  A61K2039/54 ,  A61K2039/552 ,  C07K16/468 ,  C07K2317/76 ,  C07K2319/00

Abstract: Compositions suitable for reducing symptoms of an allergic response to environmental allergens comprising molecules that specifically inhibit the ability of the allergen to bind to mast cells in an animal predisposed to having an allergic response to the allergen and methods for reducing such symptoms comprising contacting a source of the environmental allergen with such compositions. Kits, packages, medicaments, and means of communicating about the compositions and methods are also provided.

公开(公告)号：US20130236475A1

公开(公告)日：2013-09-12

申请号：US13870374

申请日：2013-04-25

Applicant: NESTEC SA

Inventor： George Wells ,  Ebenzer Satyaraj

IPC: C07K16/18

CPC classification number: C07K16/18 ,  A61K2039/505 ,  A61K2039/54 ,  A61K2039/552 ,  C07K16/468 ,  C07K2317/76 ,  C07K2319/00

Abstract: Compositions suitable for reducing symptoms of an allergic response to environmental allergens comprising molecules that specifically inhibit the ability of the allergen to bind to mast cells in an animal predisposed to having an allergic response to the allergen and methods for reducing such symptoms comprising contacting a source of the environmental allergen with such compositions. Kits, packages, medicaments, and means of communicating about the compositions and methods are also provided.

Abstract translation: 适于减轻对环境变应原的过敏反应症状的组合物，其包含特异性抑制变应原结合易感性变应原过敏反应的动物中的肥大细胞的能力的分子，以及用于减少所述症状的方法，所述方法包括： 具有这种组合物的环境变应原。 还提供了试剂盒，包装，药物以及关于组合物和方法的沟通方法。

公开(公告)号：US20150175940A1

公开(公告)日：2015-06-25

申请号：US14570310

申请日：2014-12-15

Applicant: Nestec SA

Inventor： George Wells ,  Delphine Tissot-Favre ,  Ebenezer Satyaraj ,  Juergen Eck ,  Daniel Meyer ,  Torsten Ertongur-Fauth ,  Alexander Pelzer ,  Scott Sherrill ,  Peichuan Sun

IPC: C11D3/386 ,  A01K1/015 ,  A61L9/00

CPC classification number: C11D3/38609 ,  A01K1/0155 ,  A23K20/189 ,  A23K50/40 ,  A23K50/42 ,  A23K50/48 ,  A61K38/00 ,  A61L9/00 ,  C11D3/386 ,  C11D3/38618 ,  C11D11/0011

Abstract: Formulations, compositions and products for reducing allergenic Fel d 1 from the environment are disclosed. The formulations include at least one protease that interacts with the Fel d 1 and substantially degrades allergenic epitopes on the Fel d 1. Methods of using the formulations for reducing or eliminating allergenic Fel d 1 from the environment are also disclosed.

Abstract translation: 公开了用于降低环境中致敏性Fel d 1的制剂，组合物和产品。 该制剂包括与Fel d 1相互作用的至少一种蛋白酶，并且在Fel d 1上基本上降解过敏表位。还公开了使用该制剂减少或消除来自环境的过敏性Fel d 1的方法。