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1.发明授权Method for diagnosing multiple myeloma by determining tumor rejection antigen precursors 失效通过确定肿瘤排斥抗原前体来诊断多发性骨髓瘤的方法公开(公告)号：US06210886B1
公开(公告)日：2001-04-03
申请号：US09183931
申请日：1998-10-30
IPC分类号： C12Q168
CPC分类号： C12Q1/6886 , C12Q2600/112
摘要： Methods for diagnosing multiple myeloma are disclosed. These methods are based upon the observation that tumor rejection antigen precursors are expressed in multiple myeloma. By assaying bone marrow samples, one can diagnose multiple myeloma, and also monitor the disease's progress. Therapeutic approaches to multiple myeloma are also disclosed.
摘要翻译： 公开了诊断多发性骨髓瘤的方法。 这些方法基于观察到肿瘤排斥抗原前体在多发性骨髓瘤中表达。 通过分析骨髓样本，可以诊断多发性骨髓瘤，并监测疾病的进展。 还公开了多发性骨髓瘤的治疗方法。
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2.发明授权Methods for diagnosing multiple myeloma by determining rejection antigen precursors 失效通过确定排斥抗原前体来诊断多发性骨髓瘤的方法公开(公告)号：US06387630B1
公开(公告)日：2002-05-14
申请号：US09705160
申请日：2000-11-02
IPC分类号： C12Q168
CPC分类号： C12Q1/6886 , C12Q2600/112
摘要： Methods for diagnosing multiple myeloma are disclosed. These methods are based upon the observation that tumor rejection antigen precursors are expressed in multiple myeloma. By assaying bone marrow samples, one can diagnose multiple myeloma, and also monitor the disease's progress. Therapeutic approaches to multiple myeloma are also disclosed.
摘要翻译： 公开了诊断多发性骨髓瘤的方法。 这些方法基于观察到肿瘤排斥抗原前体在多发性骨髓瘤中表达。 通过分析骨髓样本，可以诊断多发性骨髓瘤，并监测疾病的进展。 还公开了多发性骨髓瘤的治疗方法。
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3.发明授权Method for determining multiple myeloma by assaying for expression of mage genes 失效通过测定法师基因表达来确定多发性骨髓瘤的方法
公开(公告)号：US5985571A
公开(公告)日：1999-11-16
申请号：US18422
申请日：1998-02-04
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： Methods for diagnosing multiple myeloma are disclosed. These methods are based upon the observation that tumor rejection antigen precursors are expressed in multiple myeloma. By assaying bone marrow samples, one can diagnose multiple myeloma, and also monitor the disease's progress. Therapeutic approaches of multiple myeloma are also disclosed.
摘要翻译： 公开了诊断多发性骨髓瘤的方法。 这些方法基于观察到肿瘤排斥抗原前体在多发性骨髓瘤中表达。 通过分析骨髓样本，可以诊断多发性骨髓瘤，并监测疾病的进展。 还公开了多发性骨髓瘤的治疗方法。
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公开(公告)号：US6165725A
公开(公告)日：2000-12-26
申请号：US351351
申请日：1999-07-12
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： Methods for diagnosing multiple myeloma are disclosed. These methods are based upon the observation that tumor rejection antigen precursors are expressed in multiple myeloma. By assaying bone marrow samples, one can diagnose multiple myeloma, and also monitor the disease's progress. Therapeutic approaches of multiple myeloma are also disclosed.
摘要翻译： 公开了诊断多发性骨髓瘤的方法。 这些方法基于观察到肿瘤排斥抗原前体在多发性骨髓瘤中表达。 通过分析骨髓样本，可以诊断多发性骨髓瘤，并监测疾病的进展。 还公开了多发性骨髓瘤的治疗方法。
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公开(公告)号：US06271019B1
公开(公告)日：2001-08-07
申请号：US09430854
申请日：1999-10-29
IPC分类号： C12N121
CPC分类号： C07K14/4748 , A61K38/00 , C12Q1/6886 , C12Q2600/158
摘要： The invention describes leukemia associated genes, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such genes, and antibodies relating thereto. Methods and products also are provided for diagnosing and treating conditions characterized by expression of a preproTRH, tryptase-L and/or Oct-T1 gene product.
摘要翻译： 本发明描述了白血病相关基因，包括其片段和生物功能变体。 还包括由这些基因编码的多肽及其片段，以及与之相关的抗体。 还提供了用于诊断和治疗以前trR，类胰蛋白酶-L和/或Oct-T1基因产物表达为特征的病症的方法和产品。
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公开(公告)号：US5879892A
公开(公告)日：1999-03-09
申请号：US845998
申请日：1997-04-25
IPC分类号： G01N33/53 , A61K31/711 , A61K38/00 , A61K48/00 , A61P35/02 , C07K14/435 , C07K14/47 , C07K16/00 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/08 , C12Q1/68 , G01N33/566
CPC分类号： C07K14/4748 , C12Q1/6886 , A61K38/00 , C12Q2600/158
摘要： The invention describes leukemia associated genes, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such genes, and antibodies relating thereto. Methods and products also are provided for diagnosing and treating conditions characterized by expression of a preproTRH, tryptase-L and/or Oct-T1 gene product.
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公开(公告)号：US6130052A
公开(公告)日：2000-10-10
申请号：US206537
申请日：1998-12-07
IPC分类号： G01N33/53 , A61K31/711 , A61K38/00 , A61K48/00 , A61P35/02 , C07K14/435 , C07K14/47 , C07K16/00 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/08 , C12Q1/68 , G01N33/566 , G01N33/574
CPC分类号： C07K14/4748 , C12Q1/6886 , A61K38/00 , C12Q2600/158
摘要： The invention describes leukemia associated genes, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such genes, and antibodies relating thereto. Methods and products also are provided for diagnosing and treating conditions characterized by expression of a preproTRH, tryptase-L and/or Oct-T1 gene product.
摘要翻译： 本发明描述了白血病相关基因，包括其片段和生物功能变体。 还包括由这些基因编码的多肽及其片段，以及与之相关的抗体。 还提供了用于诊断和治疗以前trR，类胰蛋白酶-L和/或Oct-T1基因产物表达为特征的病症的方法和产品。
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