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    Nonsteroidal progesterone receptor modulators
    1.
    发明授权
    Nonsteroidal progesterone receptor modulators 失效
    非甾体孕激素受体调节剂

    公开(公告)号：US07408060B2

    公开(公告)日：2008-08-05

    申请号：US11473336

    申请日：2006-06-23

    申请人： Norbert Schmees ,  Ulrich Bothe ,  Wolfgang Schwede ,  Carsten Moeller ,  Ulrike Fuhrmann ,  Anja Schmidt

    发明人： Norbert Schmees ,  Ulrich Bothe ,  Wolfgang Schwede ,  Carsten Moeller ,  Ulrike Fuhrmann ,  Anja Schmidt

    IPC分类号： C07D265/02 ,  C07D265/00 ,  C07D305/12

    CPC分类号： C07D307/88 ,  C07D307/94 ,  C07D407/12

    摘要： This invention relates to nonsteroidal progesterone receptor modulators of general formula I, a process for their production, the use of progesterone receptor modulators for the production of pharmaceutical agents as well as pharmaceutical compositions that contain these compounds. The compounds according to the invention are suitable for therapy and prophylaxis of gynecological diseases, such as endometriosis, leiomyomas of the uterus, dysfunctional bleeding and dysmenorrhea, as well as for the therapy and prophylaxis of hormone-dependent tumors and for use for female birth control as well as for hormone replacement therapy.

    摘要翻译： 本发明涉及通式I的非甾体孕激素受体调节剂，其制备方法，使用孕酮受体调节剂制备药剂以及含有这些化合物的药物组合物。 根据本发明的化合物适用于治疗和预防妇科疾病，例如子宫内膜异位症，子宫平滑肌瘤，功能障碍性出血和痛经，以及用于治疗和预防激素依赖性肿瘤并用于女性避孕 以及激素替代疗法。

    Nonsteroidal progesterone receptor modulators
    2.
    发明申请
    Nonsteroidal progesterone receptor modulators 失效
    非甾体孕激素受体调节剂

    公开(公告)号：US20070142464A1

    公开(公告)日：2007-06-21

    申请号：US11473336

    申请日：2006-06-23

    申请人： Norbert Schmees ,  Ulrich Bothe ,  Wolfgang Schwede ,  Carsten Moeller ,  Ulrike Fuhrmann ,  Anja Schmidt

    发明人： Norbert Schmees ,  Ulrich Bothe ,  Wolfgang Schwede ,  Carsten Moeller ,  Ulrike Fuhrmann ,  Anja Schmidt

    IPC分类号： A61K31/365 ,  C07D311/02

    CPC分类号： C07D307/88 ,  C07D307/94 ,  C07D407/12

    摘要： This invention relates to nonsteroidal progesterone receptor modulators of general formula I, a process for their production, the use of progesterone receptor modulators for the production of pharmaceutical agents as well as pharmaceutical compositions that contain these compounds. The compounds according to the invention are suitable for therapy and prophylaxis of gynecological diseases, such as endometriosis, leiomyomas of the uterus, dysfunctional bleeding and dysmenorrhea, as well as for the therapy and prophylaxis of hormone-dependent tumors and for use for female birth control as well as for hormone replacement therapy.

    摘要翻译： 本发明涉及通式I的非甾体孕激素受体调节剂，其制备方法，使用孕酮受体调节剂制备药剂以及含有这些化合物的药物组合物。 根据本发明的化合物适用于治疗和预防妇科疾病，例如子宫内膜异位症，子宫平滑肌瘤，功能障碍性出血和痛经，以及用于治疗和预防激素依赖性肿瘤并用于女性避孕 以及激素替代疗法。