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公开(公告)号：US20220128806A1
公开(公告)日：2022-04-28
申请号：US17426012
申请日：2020-01-28
IPC分类号： G02B21/00 , G02B21/02 , G02B27/14 , G02B27/10 , G02B21/36 , G03B21/60 , G06T3/00 , G06T15/08
摘要： An imaging system includes a first finite conjugate objective at a frontal end of the system and a second finite conjugate objective at a distal end of the system. The system also includes a beam splitting or merging element positioned between the first finite conjugate objective and the second finite conjugate objective. The system also includes an excitation unit configured to direct an excitation beam into a sample positioned in front of the first finite conjugate objective. The excitation beam is in the form of an excitation plane. The system also includes an image sensor positioned facing the second finite conjugate objective. The image sensor lies in a conjugate plane of an excitation beam illumination plane at the frontal end of the system.
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公开(公告)号：US12105270B2
公开(公告)日：2024-10-01
申请号：US17426012
申请日：2020-01-28
IPC分类号： G02B21/00 , G02B21/02 , G02B21/36 , G02B27/10 , G02B27/14 , G03B21/60 , G06T3/02 , G06T15/08 , H04N25/53
CPC分类号： G02B21/0032 , G02B21/0048 , G02B21/0076 , G02B21/008 , G02B21/02 , G02B21/364 , G02B27/1006 , G02B27/141 , G03B21/60 , G06T3/02 , G06T15/08 , H04N25/53
摘要： An imaging system includes a first finite conjugate objective at a frontal end of the system and a second finite conjugate objective at a distal end of the system. The system also includes a beam splitting or merging element positioned between the first finite conjugate objective and the second finite conjugate objective. The system also includes an excitation unit configured to direct an excitation beam into a sample positioned in front of the first finite conjugate objective. The excitation beam is in the form of an excitation plane. The system also includes an image sensor positioned facing the second finite conjugate objective. The image sensor lies in a conjugate plane of an excitation beam illumination plane at the frontal end of the system.
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公开(公告)号：US10802255B2
公开(公告)日：2020-10-13
申请号：US16388466
申请日：2019-04-18
摘要： A microscopy system includes a first excitation source configured to emit a one-photon light beam and a second excitation source configured to emit a two-photon light beam. The system also includes a first optical component configured to deliver one or more of a one-photon light sheet and a two-photon light sheet, where the one-photon light sheet is based on the one-photon light beam and the two-photon light sheet is based on the two-photon light beam. The system further includes a single reflective surface at a back focal plane of the first optical component to reflect the one or more of the one-photon light sheet and the two-photon light sheet toward a sample. The single reflective surface rotates about a fixed axis situated at a cross section of the single reflective surface and the back focal plane of the first optical component.
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公开(公告)号：US20190324244A1
公开(公告)日：2019-10-24
申请号：US16388466
申请日：2019-04-18
摘要： A microscopy system includes a first excitation source configured to emit a one-photon light beam and a second excitation source configured to emit a two-photon light beam. The system also includes a first optical component configured to deliver one or more of a one-photon light sheet and a two-photon light sheet, where the one-photon light sheet is based on the one-photon light beam and the two-photon light sheet is based on the two-photon light beam. The system further includes a single reflective surface at a back focal plane of the first optical component to reflect the one or more of the one-photon light sheet and the two-photon light sheet toward a sample. The single reflective surface rotates about a fixed axis situated at a cross section of the single reflective surface and the back focal plane of the first optical component.
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