公开(公告)号：US09623589B2

公开(公告)日：2017-04-18

申请号：US14074087

申请日：2013-11-07

Applicant: Novartis AG

Inventor： Roger Biel ,  Gabriela Cocora ,  Peter Hagmann ,  Uwe Haken ,  William Jordan Hall ,  Axel Heinrich ,  Günter Lässig ,  Honghui Lu ,  Deborah J. Mulcahy ,  Carlton Pope ,  Daryl Reece ,  Bernhard Seiferling

IPC: B29C33/20 ,  B29C37/00 ,  B29C43/02 ,  B29C43/36 ,  B29D11/00 ,  B29L11/00

CPC classification number: B29C33/20 ,  B29C37/005 ,  B29C43/02 ,  B29C43/36 ,  B29D11/00125 ,  B29L2011/0016

Abstract: There is described a process for manufacturing an ophthalmic lens and an apparatus for forming an ophthalmic lens, in particular a silicone hydrogel contact lens, wherein in a mold assembly a first and a second mold half (101, 102) are first arranged in an intermediate closed position in which the mold surfaces of the two mold halves are spaced apart from each other at a distance increase (d1) of preferably 1 to 100 μm relative to a final distance (d0) in a final closed position, and wherein, during curing of the lens forming material (202), the mold surfaces (105, 106) of the mold halves (101, 102) are actively or passively moved or moving from the intermediate closed position to the final closed position, where the distance increase (d1) is 0.

公开(公告)号：US20180113236A1

公开(公告)日：2018-04-26

申请号：US15792806

申请日：2017-10-25

Applicant: Novartis AG

Inventor： Harald Bothe ,  Bernhard Seiferling ,  Heike Arndt ,  Thomas Wasse ,  Stephan Wittmar

IPC: G02B1/04 ,  G02C7/04 ,  C08L29/04 ,  C09D129/14 ,  C08L39/04 ,  C08L71/08 ,  C07H3/02 ,  C07H3/04

Abstract: The invention is generally related to soft contact lenses which comprise a polyvinylalcohol-based hydrogel lens body and a durable lubricious coating thereon which are covalently attached to the polyvinylalcohol-based hydrogel lens body through 6-membered acetal rings and to a method for producing the same.

公开(公告)号：US09914272B2

公开(公告)日：2018-03-13

申请号：US14216946

申请日：2014-03-17

Applicant: Novartis AG

Inventor： Axel Heinrich ,  Bernhard Seiferling ,  Peter Hagmann

IPC: B29D11/00 ,  B29C33/00 ,  B29C71/00 ,  B29C37/02 ,  B29L11/00

CPC classification number: B29D11/00413 ,  B29C33/00 ,  B29C37/02 ,  B29C71/0009 ,  B29C2071/0027 ,  B29C2071/0045 ,  B29D11/00125 ,  B29D11/00586 ,  B29L2011/0041

Abstract: There is described a method of separating excess lens forming material from a molded ophthalmic lens, in particular a contact lens. After polymerization and/or cross-linking of a lens forming material (P) within a mold cavity (4) of a mold (1) comprising female and male mold halves (2, 3) to form an ophthalmic lens non-polymerized and/or non-cross-linked lens forming material is flushed away from the mold halves (2, 3) with a jet of a fluid flushing medium, such as, e.g., water or a solvent or an inert gas. Subsequently the molded lens is dried. In accordance with the invention the flushing is accomplished with the mold halves (2, 3) still in the closed position. There is also described an apparatus for carrying out the method.

公开(公告)号：US09765166B2

公开(公告)日：2017-09-19

申请号：US15029363

申请日：2013-10-17

Applicant: THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD. ,  NOVARTIS AG

Inventor： Mitsuo Shibutani ,  Masahiro Saito ,  Bernhard Seiferling ,  Jiro Tsuchiya ,  Hirohiko Miura ,  Yasuo Matsuzawa

IPC: C08F2/46 ,  C08G61/04 ,  C08F218/08 ,  C08F216/06 ,  C08F218/10 ,  C08F8/12 ,  C08F8/30 ,  G02B1/04 ,  C08F216/38

CPC classification number: C08F218/08 ,  C08F8/12 ,  C08F8/30 ,  C08F216/06 ,  C08F216/38 ,  C08F218/10 ,  G02B1/043 ,  C08L29/04

Abstract: The present invention provides a crosslinkable prepolymer which can be used to produce crosslinked polymeric materials (or contact lenses containing the same) having a high strength and excellent durability. The present invention relates to a polyvinyl alcohol-based prepolymer containing a unit having a pendant 1,2-diol containing group and a unit having a specific crosslinkable functional group, as well as a molding using the same.

公开(公告)号：US20140199425A1

公开(公告)日：2014-07-17

申请号：US14216946

申请日：2014-03-17

Applicant: Novartis AG

Inventor： Axel Heinrich ,  Bernhard Seiferling ,  Peter Hagmann

IPC: B29D11/00

CPC classification number: B29D11/00413 ,  B29C33/00 ,  B29C37/02 ,  B29C71/0009 ,  B29C2071/0027 ,  B29C2071/0045 ,  B29D11/00125 ,  B29D11/00586 ,  B29L2011/0041

Abstract: There is described a method of separating excess lens forming material from a molded ophthalmic lens, in particular a contact lens. After polymerization and/or cross-linking of a lens forming material (P) within a mold cavity (4) of a mold (1) comprising female and male mold halves (2, 3) to form an ophthalmic lens non-polymerized and/or non-cross-linked lens forming material is flushed away from the mold halves (2, 3) with a jet of a fluid flushing medium, such as, e.g., water or a solvent or an inert gas. Subsequently the molded lens is dried. In accordance with the invention the flushing is accomplished with the mold halves (2, 3) still in the closed position. There is also described an apparatus for carrying out the method.

Abstract translation: 描述了从模制的眼科镜片，特别是隐形眼镜分离多余的透镜形成材料的方法。 在透镜形成材料（P）在包含阴模和阴半模（2,3）的模具（1）的模腔（4）内聚合和/或交联以形成未聚合的眼科镜片和/ 或非交联透镜形成材料用流体冲洗介质（例如水或溶剂或惰性气体）的射流冲洗离开半模（2,3）。 随后将模制的透镜干燥。 根据本发明，冲洗是通过半模（2,3）仍处于关闭位置来完成的。 还描述了一种用于执行该方法的装置。

公开(公告)号：US20140072665A1

公开(公告)日：2014-03-13

申请号：US14074087

申请日：2013-11-07

Applicant: Novartis AG

Inventor： Roger Biel ,  Gabriele Cocora ,  Peter Hagmann ,  Uwe Haken ,  William Jordan Hall ,  Axel Heinrich ,  Günter Lässig ,  Honghui Lu ,  Deborah J. Mulcahy ,  Carlton Pope ,  Daryl Reece ,  Bernhard Seiferling

IPC: B29C33/20

CPC classification number: B29C33/20 ,  B29C37/005 ,  B29C43/02 ,  B29C43/36 ,  B29D11/00125 ,  B29L2011/0016

Abstract: There is described a process for manufacturing an ophthalmic lens and an apparatus for forming an ophthalmic lens, in particular a silicone hydrogel contact lens, wherein in a mold assembly a first and a second mold half (101, 102) are first arranged in an intermediate closed position in which the mold surfaces of the two mold halves are spaced apart from each other at a distance increase (d1) of preferably 1 to 100 μm relative to a final distance (d0) in a final closed position, and wherein, during curing of the lens forming material (202), the mold surfaces (105, 106) of the mold halves (101, 102) are actively or passively moved or moving from the intermediate closed position to the final closed position, where the distance increase (d1) is 0.

Abstract translation: 描述了用于制造眼科镜片的方法和用于形成眼用透镜，特别是硅酮水凝胶隐形眼镜的装置，其中在模具组件中，第一和第二半模（101,102）首先被布置在中间体 关闭位置，其中两个半模的模具表面在最终关闭位置中相对于最终距离（d0）以优选1至100μm的距离增加（d1）彼此间隔开，并且其中在固化期间 透镜形成材料（202）的两个半模（101,102）的模具表面（105,106）被主动地或被动地从中间关闭位置移动或移动到最终关闭位置，其中距离增加（d1 ）为0。