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公开(公告)号:US20210323947A1
公开(公告)日:2021-10-21
申请号:US17235120
申请日:2021-04-20
Applicant: Novartis AG , Katholieke Universiteit Leuven , Korea Research Institute of Chemical Technology
Inventor: Johan NEYTS , Daniel POON , Keith Bruce PFISTER
IPC: C07D405/12 , C07D405/14 , C07D307/93 , A61K45/06 , A61P31/14
Abstract: The invention provides compounds of Formula (I): as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.
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公开(公告)号:US20250090491A1
公开(公告)日:2025-03-20
申请号:US18797480
申请日:2024-08-07
Applicant: Novartis AG , Katholieke Universiteit Leuven , Korea Research Institute of Chemical Technology
Inventor: Johan NEYTS , Daniel POON , Keith Bruce PFISTER , Young-Sik JUNG , Soo Bong HAN , Yashwardhan R. MALPANI , Prashant CHAKRASALI , Sang-Ho LEE , Chong-Kyo LEE , Chonsaeng KIM , Jin Soo SHIN , Hae Soo KIM
IPC: A61K31/343 , A61P31/14 , C07D307/93
Abstract: This disclosure provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.
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公开(公告)号:US20210322362A1
公开(公告)日:2021-10-21
申请号:US17235140
申请日:2021-04-20
Applicant: Novartis AG , Katholieke Universiteit Leuven , Korea Research Institute of Chemical Technology
Inventor: Johan NEYTS , Daniel POON , Keith Bruce PFISTER
IPC: A61K31/343 , C07D307/93 , A61P31/14
Abstract: This disclosure provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.
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公开(公告)号:US20250011334A1
公开(公告)日:2025-01-09
申请号:US18743020
申请日:2024-06-13
Applicant: Novartis AG
Inventor: Rama JAIN , Dennis Christofer KOESTER , James R. MANNING , Vanessa MARX , Daniel POON , James Clifford SUTTON , Benjamin R. TAFT , Lifeng WAN , Aregahegn YIFRU , Qian ZHAO
IPC: C07D487/14 , A61K31/5025 , A61K31/53 , A61K31/5365 , A61K31/5383 , A61K31/551 , A61P31/16 , C07D471/14 , C07D498/14
Abstract: The invention provides compounds of Formula (1): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.
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公开(公告)号:US20190247392A1
公开(公告)日:2019-08-15
申请号:US16210968
申请日:2018-12-05
Applicant: Novartis AG
Inventor: Jeffrey T. BAGDANOFF , Yu DING , Wooseok HAN , Zilin HUANG , Qun JIANG , Xianming JIN , Xiang KOU , Patrick LEE , Mika LINDVALL , Zhongcheng MIN , Yue PAN , Sabina PECCHI , Keith Bruce PFISTER , Daniel POON , Vivek RAUNIYAR , Xiaojing Michael WANG , Qiong ZHANG , Jianguang ZHOU , Shejin ZHU
IPC: A61K31/497 , A61K31/5355 , A61K31/4436 , A61K31/4433 , A61K31/44 , C07D403/06 , C07D401/12 , C07D401/06 , C07D213/73 , C07D413/14 , C07D241/20 , C07D401/04 , C07D405/04 , C07D405/14 , C07D409/04 , C07D498/04 , A61K31/4439 , A61K31/4545 , A61K31/4965 , A61K31/506 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K45/06
Abstract: The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.
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公开(公告)号:US20180057501A1
公开(公告)日:2018-03-01
申请号:US15686652
申请日:2017-08-25
Applicant: Novartis AG
Inventor: Rama JAIN , Dennis Christofer KOESTER , James R. MANNING , Vanessa MARX , Daniel POON , James Clifford SUTTON , Benjamin R. TAFT , Lifeng WAN , Aregahegn YIFRU , Qian ZHAO
IPC: C07D487/14 , C07D498/14 , C07D471/14
CPC classification number: C07D487/14 , C07D471/14 , C07D498/14
Abstract: The invention provides compounds of Formula (I): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.
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公开(公告)号:US20180028532A1
公开(公告)日:2018-02-01
申请号:US15672568
申请日:2017-08-09
Applicant: Novartis AG
Inventor: Jeffrey T. BAGDANOFF , Yu DING , Wooseok HAN , Zilin HUANG , Qun JIANG , Xianming JIN , Xiang KOU , Patrick LEE , Mika LINDVALL , Zhongcheng MIN , Yue PAN , Sabina PECCHI , Keith Bruce PFISTER , Daniel POON , Vivek RAUNIYAR , Xiaojing Michael WANG , Qiong ZHANG , Jianguang ZHOU , Shejin ZHU
IPC: A61K31/497 , A61K31/4433 , A61K31/5355 , A61K31/44 , A61K31/4436
CPC classification number: A61K31/497 , A61K31/44 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/4545 , A61K31/4965 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K45/06 , A61K2121/00 , C07D213/73 , C07D241/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D498/04
Abstract: The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.
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