公开(公告)号：US20190247392A1

公开(公告)日：2019-08-15

申请号：US16210968

申请日：2018-12-05

Applicant: Novartis AG

Inventor： Jeffrey T. BAGDANOFF ,  Yu DING ,  Wooseok HAN ,  Zilin HUANG ,  Qun JIANG ,  Xianming JIN ,  Xiang KOU ,  Patrick LEE ,  Mika LINDVALL ,  Zhongcheng MIN ,  Yue PAN ,  Sabina PECCHI ,  Keith Bruce PFISTER ,  Daniel POON ,  Vivek RAUNIYAR ,  Xiaojing Michael WANG ,  Qiong ZHANG ,  Jianguang ZHOU ,  Shejin ZHU

IPC: A61K31/497 ,  A61K31/5355 ,  A61K31/4436 ,  A61K31/4433 ,  A61K31/44 ,  C07D403/06 ,  C07D401/12 ,  C07D401/06 ,  C07D213/73 ,  C07D413/14 ,  C07D241/20 ,  C07D401/04 ,  C07D405/04 ,  C07D405/14 ,  C07D409/04 ,  C07D498/04 ,  A61K31/4439 ,  A61K31/4545 ,  A61K31/4965 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/5383 ,  A61K31/553 ,  A61K45/06

Abstract: The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.

公开(公告)号：US20180028532A1

公开(公告)日：2018-02-01

申请号：US15672568

申请日：2017-08-09

Applicant: Novartis AG

Inventor： Jeffrey T. BAGDANOFF ,  Yu DING ,  Wooseok HAN ,  Zilin HUANG ,  Qun JIANG ,  Xianming JIN ,  Xiang KOU ,  Patrick LEE ,  Mika LINDVALL ,  Zhongcheng MIN ,  Yue PAN ,  Sabina PECCHI ,  Keith Bruce PFISTER ,  Daniel POON ,  Vivek RAUNIYAR ,  Xiaojing Michael WANG ,  Qiong ZHANG ,  Jianguang ZHOU ,  Shejin ZHU

IPC: A61K31/497 ,  A61K31/4433 ,  A61K31/5355 ,  A61K31/44 ,  A61K31/4436

CPC classification number: A61K31/497 ,  A61K31/44 ,  A61K31/4433 ,  A61K31/4436 ,  A61K31/4439 ,  A61K31/4545 ,  A61K31/4965 ,  A61K31/506 ,  A61K31/5355 ,  A61K31/5377 ,  A61K31/5383 ,  A61K31/553 ,  A61K45/06 ,  A61K2121/00 ,  C07D213/73 ,  C07D241/20 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D403/06 ,  C07D405/04 ,  C07D405/14 ,  C07D409/04 ,  C07D413/14 ,  C07D498/04

Abstract: The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.