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公开(公告)号：US11802152B2
公开(公告)日：2023-10-31
申请号：US17539335
申请日：2021-12-01
Applicant: Novartis AG
Inventor： Brian Boettcher , Shari Lynn Caplan , Regis Cebe , Guochun Li , John A. Taraszka , Fangmin Xu , David Langdon Yowe
CPC classification number: C07K16/28 , A61P3/00 , A61K39/001107 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/92 , C07K2317/94 , C07K2318/00
Abstract: The present invention relates to monoclonal antibodies and antigen-binding fragments thereof that bind to human β-klotho, and pharmaceutical compositions and methods of treatment comprising the same.
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公开(公告)号：US20200223917A1
公开(公告)日：2020-07-16
申请号：US16588063
申请日：2019-09-30
Inventor： Catherine Anne Sabatos-Peyton , Barbara Brannetti , Alan S. Harris , Thomas Huber , Thomas Pietzonka , Jennifer Marie Mataraza , Walter A. Blattler , Daniel J. Hicklin , Maximiliano Vasquez , Rosemarie H. DeKruyff , Dale T. Umetsu , Gordon James Freeman , Tiancen Hu , John A. Taraszka , Fangmin Xu
IPC: C07K16/28 , G01N33/574 , A61K39/395 , A61K45/06 , G01N33/68
Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
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公开(公告)号：US20150218274A1
公开(公告)日：2015-08-06
申请号：US14610837
申请日：2015-01-30
Inventor： Catherine Anne Sabatos-Peyton , Barbara Brannetti , Alan S. Harris , Thomas Huber , Thomas Pietzonka , Jennifer Marie Mataraza , Walter A. Blattler , Daniel J. Hicklin , Maximiliano Vasquez , Rosemarie H. DeKruyff , Dale T. Umetsu , Gordon James Freeman , Tiancen Hu , John A. Taraszka , Fangmin Xu
IPC: C07K16/28 , A61K39/395 , A61K45/06
CPC classification number: C07K16/2803 , A61K39/3955 , A61K39/39558 , A61K45/06 , C07K2299/00 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/6893
Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
Abstract translation: 公开了特异性结合TIM-3的抗体分子。 抗TIM-3抗体分子可用于治疗，预防和/或诊断免疫，癌性或感染性疾病和/或病症。
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公开(公告)号：US10435460B2
公开(公告)日：2019-10-08
申请号：US15829115
申请日：2017-12-01
Applicant: Novartis AG
Inventor： Johanna Abend , Zorica Dragic , Adam Lloyd Feire , Mark Knapp , Steven Kovacs , Elisabetta Traggiai , Lichun Wang , Yongqiang Wang , Danqing Wu , Qilong Wu , Fangmin Xu
Abstract: The present invention relates to anti-VP1 antibodies, antibody fragments, and their uses for the prevention and treatment of polyoma virus infection and associated diseases.
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公开(公告)号：US20180207273A1
公开(公告)日：2018-07-26
申请号：US15747326
申请日：2016-07-28
Applicant: Glenn Dranoff , Catherine Anne Sabatos-Peyton , Barbara Brannetti , Alan S. Harris , Thomas Huber , Thomas Pietzonka , Jennifer Marie Mataraza , Walter A. Blattler , Daniel J. Hicklin , Maximiliano Vasquez , Rosemarie H. DeKruyff , Dale T. Umetsu , Gordon James Freeman , Tiancen Hu , John A. Taraszka , Fangmin Xu , Novartis AG , DANA-FARBER CANCER INSTITUTE, INC. , Children's Medical Center Corporation
Inventor： Glenn Dranoff , Catherine Anne Sabatos-Peyton , Barbara Brannetti , Alan S. Harris , Thomas Huber , Thomas Pietzonka , Jennifer Marie Mataraza , Walter A. Blattler , Daniel J. Hicklin , Maximiliano Vasquez , Rosemarie H. DeKruyff , Dale T. Umetsu , Gordon James Freeman , Tiancen Hu , John A. Taraszka , Fangmin Xu
IPC: A61K39/395 , A61K45/06 , A61P35/00
CPC classification number: A61K39/39566 , A61K39/00 , A61K39/3955 , A61K45/06 , A61K2039/507 , A61P35/00 , C07K16/2803 , C07K2299/00 , C07K2317/24 , C07K2317/34 , C07K2317/76 , C07K2317/94 , A61K2300/00
Abstract: Combination therapies comprising antibody molecules that specifically bind to TIM-3 are disclosed. The combination therapies can be used to treat or prevent cancerous or infectious conditions and disorders.
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Patent Agency Ranking
公开(公告)号：US20170190777A1
公开(公告)日：2017-07-06
申请号：US15462585
申请日：2017-03-17
Inventor： Catherine Anne Sabatos-Peyton , Barbara Brannetti , Alan S. Harris , Thomas Huber , Thomas Pietzonka , Jennifer Marie Mataraza , Walter A. Blattler , Daniel J. Hicklin , Maximiliano Vasquez , Rosemarie H. DeKruyff , Dale T. Umetsu , Gordon James Freeman , Tiancen Hu , John A. Taraszka , Fangmin Xu
IPC: C07K16/28
CPC classification number: C07K16/2803 , A61K39/3955 , A61K39/39558 , A61K45/06 , C07K2299/00 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/6893
Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
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公开(公告)号：US11639378B2
公开(公告)日：2023-05-02
申请号：US17502910
申请日：2021-10-15
Applicant: Novartis AG
Inventor： Johanna Abend , Zorica Dragic , Adam Lloyd Feire , Mark Knapp , Steven Kovacs , Elisabetta Traggiai , Lichun Wang , Yongqiang Wang , Danqing Wu , Qilong Wu , Fangmin Xu
IPC: A61K39/395 , C07K16/08 , A61K39/42 , A61K45/06 , A61K9/19
Abstract: The present invention relates to anti-VP1 antibodies, antibody fragments, and their uses for the prevention and treatment of polyoma virus infection and associated diseases.
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公开(公告)号：US20220363735A1
公开(公告)日：2022-11-17
申请号：US17502910
申请日：2021-10-15
Applicant: Novartis AG
Inventor： Johanna ABEND , Zorica DRAGIC , Adam Lloyd FEIRE , Mark KNAPP , Steven KOVACS , Elisabetta TRAGGIAI , Lichun WANG , Yongqiang WANG , Danqing WU , Qilong WU , Fangmin Xu
Abstract: The present invention relates to anti-VP 1 antibodies, antibody fragments, and their uses for the prevention and treatment of polyoma virus infection and associated diseases.
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公开(公告)号：US11161894B2
公开(公告)日：2021-11-02
申请号：US16657855
申请日：2019-10-18
Applicant: Novartis AG
Inventor： Johanna Abend , Zorica Dragic , Adam Lloyd Feire , Mark Knapp , Steven Kovacs , Elisabetta Traggiai , Lichun Wang , Yongqiang Wang , Danqing Wu , Qilong Wu , Fangmin Xu
Abstract: The present invention relates to anti-VP1 antibodies, antibody fragments, and their uses for the prevention and treatment of polyoma virus infection and associated diseases.
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公开(公告)号：US10981990B2
公开(公告)日：2021-04-20
申请号：US16841029
申请日：2020-04-06
Applicant: Novartis AG , DANA-FARBER CANCER INSTITUTE, INC. , The Children's Medical Center Corporation
Inventor： Catherine Anne Sabatos-Peyton , Barbara Brannetti , Alan S. Harris , Thomas Huber , Thomas Pietzonka , Jennifer Marie Mataraza , Walter A. Blattler , Daniel J. Hicklin , Maximiliano Vasquez , Rosemarie H. DeKruyff , Dale T. Umetsu , Gordon James Freeman , Tiancen Hu , John A. Taraszka , Fangmin Xu
IPC: A61K39/395 , C07K16/28 , G01N33/574 , A61K45/06 , G01N33/68
Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
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