公开(公告)号：US09718792B2

公开(公告)日：2017-08-01

申请号：US15454187

申请日：2017-03-09

Applicant: Novartis AG

Inventor： Jiping Fu ,  Xianming Jin ,  Subramanian Karur ,  Guillaume LaPointe ,  Patrick Lee ,  Zachary Kevin Sweeney

IPC: C07D417/10 ,  C07D261/04 ,  A61K31/42 ,  C07D413/04 ,  A61K31/4439 ,  C07D413/10 ,  A61K31/5377 ,  A61K31/427 ,  A61K31/422 ,  A61K45/06

CPC classification number: C07D261/04 ,  A61K31/42 ,  A61K31/421 ,  A61K31/422 ,  A61K31/427 ,  A61K31/4439 ,  A61K31/5377 ,  A61K45/06 ,  C07D413/04 ,  C07D413/10 ,  C07D417/10

Abstract: This invention pertains generally to compounds of Formula I and compositions containing such compounds, as well as methods of using such compounds to treat bacterial infections. In certain aspects, the invention pertains to methods and compositions for treating infections caused by Gram-negative bacteria.