In vivo pre-surgical characterization of cataractous lenses

    公开(公告)号:US10973404B2

    公开(公告)日:2021-04-13

    申请号:US15958956

    申请日:2018-04-20

    Applicant: Novartis AG

    Abstract: Systems and methods are provided for in vivo pre-surgical characterization of lenses, such as cataractous lenses. A method comprises obtaining an electromagnetically-measured value related to the axial thickness of the lens, obtaining an ultrasound-measured value related to the axial thickness of the lens, calculating a relationship value based upon the electromagnetically-measured value and the ultrasound-measured value, and determining a mechanical property value based upon the calculated relationship value. The mechanical property may relate to lens hardness, rigidity, or density, or the amount of energy for a phacoemulsification procedure. A system may comprise an optical interferometer for measuring data to obtain the electromagnetically-measured value and an ultrasound biometer for measuring data to obtain the ultrasound-measured value.

    ULTRAVIOLET LASER VITRECTOMY PROBE
    2.
    发明申请

    公开(公告)号:US20190201238A1

    公开(公告)日:2019-07-04

    申请号:US16219139

    申请日:2018-12-13

    Applicant: Novartis AG

    Abstract: Provided herein is a vitrectomy probe for treating an eye of a patient. In one or more embodiments, a vitrectomy probe may include a body, and a disruption element extending from the body, wherein the disruption element includes a needle having a main lumen and a port at a distal end thereof. The disruption element may further include an ultraviolet (UV) optical fiber projecting a UV laser beam for irradiating an area proximate the port. In some embodiments, a UV light source is optically connected with the UV optical fiber, the UV light source generating the UV laser beam in a spectral range of approximately 190-220 nanometers to target collagen fibers of a vitreous material entering the port.

    HYPERCHROMATIC PRESYBYOPIA-CORRECTING INTRAOCULAR LENSES

    公开(公告)号:US20190110889A1

    公开(公告)日:2019-04-18

    申请号:US16158732

    申请日:2018-10-12

    Applicant: Novartis AG

    Abstract: An ophthalmic device includes at least one ophthalmic lens and at least one diffractive structure for the at least one ophthalmic lens. The ophthalmic lens(es) have at least one base focal length and a base power for a first wavelength of visible light. The diffractive structure(s) have a chromatic aberration such that the diffractive structure(s) have a first power for the first wavelength of visible light and a second power for a second wavelength of visible light. A difference between the first power and the second power is at least two diopters.

    BIREFRINGENT LENS FOR LASER BEAM DELIVERY
    4.
    发明申请

    公开(公告)号:US20180360657A1

    公开(公告)日:2018-12-20

    申请号:US16003175

    申请日:2018-06-08

    Applicant: Novartis AG

    Abstract: An ophthalmic laser system includes a laser engine to generate a beam of femtosecond laser pulses, a laser scanner to scan each laser pulse of the beam in three dimensions according to a scan pattern, and a compound lens comprising a glass lens and a birefringent lens, the compound lens arranged to receive the scanned beam and configured to split each laser pulse of the scanned beam into an ordinary pulse and an extraordinary pulse, producing an ordinary beam comprising ordinary pulses and an extraordinary beam comprising extraordinary pulses. A particular ordinary pulse and a particular extraordinary pulse split from a particular laser pulse are spatially separated in depth along an optical axis of the compound lens, by a distance greater than or equal to 5 μm, and temporally separated by a delay greater than or equal to a pulse duration of the femtosecond laser pulses. An objective is configured to focus the ordinary beam and the extraordinary beam within an ophthalmic target.

    IN VIVO PRE-SURGICAL CHARACTERIZATION OF CATARACTOUS LENSES

    公开(公告)号:US20180317763A1

    公开(公告)日:2018-11-08

    申请号:US15958956

    申请日:2018-04-20

    Applicant: Novartis AG

    Abstract: Systems and methods are provided for in vivo pre-surgical characterization of lenses, such as cataractous lenses. A method comprises obtaining an electromagnetically-measured value related to the axial thickness of the lens, obtaining an ultrasound-measured value related to the axial thickness of the lens, calculating a relationship value based upon the electromagnetically-measured value and the ultrasound-measured value, and determining a mechanical property value based upon the calculated relationship value. The mechanical property may relate to lens hardness, rigidity, or density, or the amount of energy for a phacoemulsification procedure. A system may comprise an optical interferometer for measuring data to obtain the electromagnetically-measured value and an ultrasound biometer for measuring data to obtain the ultrasound-measured value.

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