公开(公告)号：US10398312B2

公开(公告)日：2019-09-03

申请号：US15882888

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B3/13 ,  A61B3/00 ,  G02B21/06 ,  A61B90/30 ,  G02B21/00 ,  H01S3/00

Abstract: Frequency-based mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A laser modulator may introduce frequency modulation to laser light to generate a homogeneous illumination field due to increased mode mixing in the optical fiber.

公开(公告)号：US20180214021A1

公开(公告)日：2018-08-02

申请号：US15882888

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B3/13 ,  A61B3/00 ,  G02B21/00 ,  G02B21/06 ,  A61B90/30

CPC classification number: A61B3/13 ,  A61B3/0008 ,  A61B90/30 ,  A61B2090/306 ,  G02B21/0012 ,  G02B21/06 ,  H01S3/005 ,  H01S3/0057 ,  H01S3/0085

Abstract: Frequency-based mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A laser modulator may introduce frequency modulation to laser light to generate a homogeneous illumination field due to increased mode mixing in the optical fiber.

公开(公告)号：US09782063B2

公开(公告)日：2017-10-10

申请号：US14571389

申请日：2014-12-16

Applicant: Novartis AG

Inventor： Gerald David Bacher ,  Ronald T. Smith

IPC: G02B6/00 ,  A61B3/00 ,  G02B6/42 ,  F21V8/00 ,  A61B90/30

CPC classification number: A61B3/0008 ,  A61B2090/306 ,  A61B2560/0276 ,  A61B2562/146 ,  A61B2562/228 ,  G02B6/0006 ,  G02B6/4214 ,  G02B6/4225 ,  G02B6/4286 ,  G02B6/4292

Abstract: An optical coupling efficiency detection assembly includes a first housing accommodating a beam splitter and a fiber port, a second housing accommodating a ferrule enclosing a monitoring fiber, and an attachment block attaching the first housing to the second housing to establish a parfocal arrangement among the beam splitter, the fiber port, and the ferrule. Further, an assembly method for the optical coupling efficiency detection assembly is disclosed. The assembly method may include providing a beam splitter and a fiber port in a first housing, providing a ferrule enclosing a monitoring fiber in a second housing, and attaching the second housing to the first housing via an attachment block to establish a parfocal arrangement among the beam splitter, the fiber port, and the ferrule.

公开(公告)号：US20190201238A1

公开(公告)日：2019-07-04

申请号：US16219139

申请日：2018-12-13

Applicant: Novartis AG

Inventor： Gerald David Bacher ,  Zsolt Bor ,  Mikhail Ovchinnikov

IPC: A61F9/007 ,  A61B90/30 ,  A61F9/008

CPC classification number: A61F9/00736 ,  A61B90/30 ,  A61B2090/306 ,  A61F9/008 ,  A61F2009/00863 ,  A61F2009/00874 ,  A61F2009/00887

Abstract: Provided herein is a vitrectomy probe for treating an eye of a patient. In one or more embodiments, a vitrectomy probe may include a body, and a disruption element extending from the body, wherein the disruption element includes a needle having a main lumen and a port at a distal end thereof. The disruption element may further include an ultraviolet (UV) optical fiber projecting a UV laser beam for irradiating an area proximate the port. In some embodiments, a UV light source is optically connected with the UV optical fiber, the UV light source generating the UV laser beam in a spectral range of approximately 190-220 nanometers to target collagen fibers of a vitreous material entering the port.

公开(公告)号：US20190175407A1

公开(公告)日：2019-06-13

申请号：US16217383

申请日：2018-12-12

Applicant: Novartis AG

Inventor： Gerald David Bacher ,  Mark Harrison Farley ,  Alireza Mirsepassi ,  Ronald T. Smith

IPC: A61F9/008 ,  A61B90/30

Abstract: Systems and methods for creating multi-spot laser light beams, multiplexing an illumination light and the multi-spot laser light beams, delivering the multiplexed light to a surgical handpiece via a multi-core optical fiber cable, and delivering the multiplexed light onto patient anatomy.

公开(公告)号：US20180214239A1

公开(公告)日：2018-08-02

申请号：US15882815

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B90/30 ,  A61F9/008 ,  A61B17/02

CPC classification number: A61B90/30 ,  A61B3/0008 ,  A61B17/0231 ,  A61B2090/306 ,  A61F9/008 ,  G02B6/0006 ,  G02B23/2469 ,  G02B26/0825 ,  G02B26/0883

Abstract: Mechanical optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A mechanical optical element, such as a rotating prism or a mirror membrane, may impart motion to an incident beam entering the optical fiber to generate a homogeneous illumination field from a coherent light source.

公开(公告)号：US20180214237A1

公开(公告)日：2018-08-02

申请号：US15882758

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B90/30 ,  A61B17/02 ,  A61F9/007 ,  A61B3/00

Abstract: Fiber-based mode mixing techniques may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibrating fiber mechanism may impart mechanical motion to a portion of the optical fiber to generate a homogeneous illumination field from a coherent light source.

公开(公告)号：US10939815B2

公开(公告)日：2021-03-09

申请号：US15793656

申请日：2017-10-25

Applicant: Novartis AG

Inventor： Mark David LaBelle ,  Ryan Takakawa ,  Alireza Mirsepassi ,  Cesario Dos Santos ,  Gerald David Bacher ,  Eyad Ammari

IPC: A61F9/008 ,  A61B3/00 ,  A61B90/30 ,  A61F9/007 ,  F21V8/00

Abstract: The present disclosure provides a vitreous visualization system including a general light source, a general conduit that transmits light from the general light source through a conduit portion of a general illumination optical fiber, and a combined vitreous visualization and general illumination tool that receives light from the general conduit. The combined vitreous visualization tool includes a vitreous visualization light source, a controller for the vitreous visualization light source, a vitreous visualization optical fiber, a tool portion of the general illumination optical fiber, and a probe tip through which at least parts of both the vitreous visualization optical fiber and the tool portion of the general illumination optical fiber pass.

公开(公告)号：US10918522B2

公开(公告)日：2021-02-16

申请号：US16002465

申请日：2018-06-07

Applicant: NOVARTIS AG

Inventor： Gerald David Bacher ,  Brian William McDonell ,  Michael J. Papac

IPC: A61F9/00 ,  A61F9/008 ,  G02B6/35 ,  G02B6/02

Abstract: In a general aspect, a vitrectomy system is adapted to use photodisruption to rupture eye tissue. In some aspects, a photodisruption-based vitrectomy system includes a laser source configured to generate optical pulses having a pulse energy greater than a threshold energy for causing photodisruption in vitreous humor. The system also includes an optical switching device arranged to receive an output of the laser source, and an optical fiber with multiple cores that is arranged to receive an output of the optical switching device. The optical switching device is configured to select a core of the optical fiber and direct optical pulses received from the laser source into the selected core.

公开(公告)号：US10779905B2

公开(公告)日：2020-09-22

申请号：US15882790

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B90/30 ,  A61B17/02 ,  A61F9/007 ,  G02B27/48 ,  A61B3/00 ,  G02B21/00

Abstract: Focusing optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibration stage may impart mechanical motion to a condenser lens to generate a homogeneous illumination field from a coherent light source.