公开(公告)号：US20140134691A1

公开(公告)日：2014-05-15

申请号：US14118856

申请日：2012-05-25

Applicant: Novozymes A/S

Inventor： Peter Olsen ,  Lars Christensen ,  Steen Joergensen ,  Torsten Regueira ,  Bjarke Christensen ,  Brian Kobmann ,  Thomas Grotkjaer

IPC: C12P7/04 ,  C12P5/02

CPC classification number: C12P7/04 ,  C12N1/20 ,  C12P5/026

Abstract: Described herein are host cells comprising lactate dehydrogenase activity, lactaldehyde dehydrogenase activity, lactaldehyde reductase activity, propanediol dehydratase activity, and/or n-propanol dehydrogenase activity, wherein the cells are capable of producing n-propanol. Also described are methods of producing n-propanol comprising (a) cultivating the host cells having lactate dehydrogenase activity, lactaldehyde dehydrogenase activity, lactaldehyde reductase activity, propanediol dehydratase activity, and/or n-propanol dehydrogenase activity in a medium under suitable conditions to produce n-propanol; and (b) recovering the n-propanol. Methods of producing polypropylene from the recombinant n-propanol are also provided.

Abstract translation: 本文描述了包含乳酸脱氢酶活性，乳醛脱氢酶活性，乳醛还原酶活性，丙二醇脱水酶活性和/或正丙醇脱氢酶活性的宿主细胞，其中细胞能够产生正丙醇。 还描述了生产正丙醇的方法，其包括（a）在合适条件下培养具有乳酸脱氢酶活性，内醛脱氢酶活性，乳醛还原酶活性，丙二醇脱水酶活性和/或正丙醇脱氢酶活性的宿主细胞，以产生 正丙醇 和（b）回收正丙醇。 还提供了从重组正丙醇制备聚丙烯的方法。

公开(公告)号：US20140349351A1

公开(公告)日：2014-11-27

申请号：US14351108

申请日：2012-10-11

Applicant: Novozymes A/S

Inventor： Jacob Skibsted Jensen ,  Thomas Grotkjaer ,  Sven Pedersen ,  Rolf Ringborg

IPC: C07D307/50 ,  C12P17/04

CPC classification number: C07D307/50 ,  C07D307/46 ,  C12P17/04

Abstract: The present invention relates to a process for producing 5-hydroxymethylfurfural (HMF) from fructose in a single-phase aqueous solution comprising an organic solvent.

Abstract translation: 本发明涉及在含有机溶剂的单相水溶液中从果糖生产5-羟甲基糠醛（HMF）的方法。