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    PHOTOACOUSTIC IMAGING DEVICE AND METHOD
    1.
    发明申请
    PHOTOACOUSTIC IMAGING DEVICE AND METHOD 有权

    公开(公告)号：US20210204817A1

    公开(公告)日：2021-07-08

    申请号：US17207019

    申请日：2021-03-19

    申请人： OLYMPUS CORPORATION

    发明人： Yoshiaki MURAYAMA ,  Atsushi DOI ,  Kentaro IMOTO

    IPC分类号： A61B5/00

    摘要： A photoacoustic imaging device includes an excitation light irradiation unit that irradiates the same position of a specimen with two or more beams of pulsed excitation light separated by an irradiation time interval, a detector that detects an acoustic wave generated at the position irradiated with the excitation light by the excitation light irradiation unit, a generator that generates an image of the specimen based on the detected acoustic wave, and a controller that controls the irradiation time interval, the acoustic wave generated with a single beam of pulsed excitation light has multiple positive peaks that periodically occur, and the controller controls the irradiation time interval into a timing at which a second positive peak of the acoustic wave generated with the preceding excitation light is superimposed on a first positive peak of the acoustic wave generated with the subsequent excitation light.

    SIGNAL PROCESSING DEVICE, PHOTOACOUSTIC WAVE IMAGE-ACQUISITION DEVICE, AND SIGNAL PROCESSING METHOD
    2.
    发明申请
    SIGNAL PROCESSING DEVICE, PHOTOACOUSTIC WAVE IMAGE-ACQUISITION DEVICE, AND SIGNAL PROCESSING METHOD 审中-公开

    公开(公告)号：US20190339372A1

    公开(公告)日：2019-11-07

    申请号：US16517627

    申请日：2019-07-21

    申请人： OLYMPUS CORPORATION

    发明人： Yoshiaki MURAYAMA

    IPC分类号： G01S7/52 ,  G01S15/89

    摘要： A signal processing device according to the present invention is a signal processing device that processes data of a detected ultrasound waveform representing a temporal change in the intensity of ultrasound generated at a measurement position in a specimen and includes: a comparison unit that compares a predetermined standard ultrasound waveform and the detected ultrasound waveform at the measurement position and that calculates a degree of similarity between the predetermined standard ultrasound waveform and the detected ultrasound waveform; and a discrimination unit for discriminating whether or not the measurement position corresponds to a predetermined examination subject on the basis of the degree of similarity.

    PHOTOACOUSTIC MICROSCOPE
    4.
    发明申请
    PHOTOACOUSTIC MICROSCOPE 审中-公开
    光电显微镜

    公开(公告)号：US20160305912A1

    公开(公告)日：2016-10-20

    申请号：US15191750

    申请日：2016-06-24

    申请人： OLYMPUS CORPORATION

    发明人： Yoshiaki MURAYAMA

    IPC分类号： G01N29/06 ,  G01N29/24 ,  A61B5/00 ,  G01N29/44

    CPC分类号： G01N29/0681 ,  A61B5/0095 ,  G01N29/032 ,  G01N29/2418 ,  G01N29/44 ,  G01N29/4427 ,  G01N2291/02483 ,  G01N2291/0289 ,  G01N2291/263

    摘要： A photoacoustic microscope includes a light source, an objective lens, a light scanner, a photoacoustic wave detector, and a calculation unit. The light source emits excitation light. The objective lens focuses the excitation light within a specimen. The light scanner scans the specimen with the excitation light. The photoacoustic wave detector detects photoacoustic waves. The calculation unit uses a correlation coefficient to calculate a shift in waveform due to a change over time in photoacoustic waves between a standard position and a calculation position. The calculation unit calculates the depth from the standard position at the calculation position based on the shift.

    摘要翻译： 光声显微镜包括光源，物镜，光扫描器，光声波检测器和计算单元。 光源发射激发光。 物镜将激发光聚焦在样品内。 光扫描仪用激发光扫描样品。 光声波检测器检测光声波。 计算单元使用相关系数来计算由于在标准位置和计算位置之间的光声中随时间的变化而导致的波形偏移。 计算单元基于移位计算在计算位置处的标准位置的深度。

    PHOTOACOUSTIC IMAGING DEVICE
    5.
    发明申请
    PHOTOACOUSTIC IMAGING DEVICE 有权

    公开(公告)号：US20210208109A1

    公开(公告)日：2021-07-08

    申请号：US17207897

    申请日：2021-03-22

    申请人： OLYMPUS CORPORATION

    发明人： Yoshiaki MURAYAMA ,  Atsushi DOI ,  Kentaro IMOTO

    IPC分类号： G01N29/24 ,  G01N29/28 ,  G01N29/06

    摘要： A photoacoustic imaging device includes an irradiator irradiating a specimen with excitation light, a detection unit detecting an acoustic wave at an irradiated position, a propagation body including a bag-shaped body including a film deforming in conformity with a surface shape of the specimen, an interior of the bag-shaped body being filled with an acoustic wave propagation medium, and a processor including hardware and configured to generate an image based on the detected acoustic wave, wherein the propagation body is disposed between the detection unit and the specimen, without interposing any air layers, and moves along with relative movement of the detection unit and the specimen, the detection unit includes an optics collecting the acoustic wave, the propagation body is attached to the optics, and a difference of refractive indexes between the optics and the propagation body is smaller than a difference of refractive indexes between the optics and air.