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公开(公告)号:US11096910B2
公开(公告)日:2021-08-24
申请号:US15746246
申请日:2016-07-22
申请人: OMEICOS THERAPEUTICS GMBH , BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , MAX DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN
发明人: Robert Fischer , Anne Konkel , Tim Wesser , Philipp Westphal , Wolf-Hagen Schunk , Christina Westphal , John Russell Falck
IPC分类号: A61P9/00 , A61K31/08 , A61K31/202 , A61K31/18 , C07C233/56 , C07C275/20 , C07C311/17 , C07D257/04 , C07C311/51 , C07D307/60 , C07D295/192 , C07D309/14 , C07D249/12 , C07D263/48 , A61K31/557 , A61P9/10 , A61P9/06 , A61P9/04 , A61K9/00 , A61K9/12 , A61K31/17 , A61K31/4196 , A61K31/5375
摘要: The present invention relates to compounds according to general formula (I) which are metabolically robust analogues of bioactive lipid mediators derived from omega-3 polyunsaturated fatty acids (n-3 PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for the treatment or prevention of cardiovascular diseases.