公开(公告)号：US20220331343A1

公开(公告)日：2022-10-20

申请号：US17626731

申请日：2020-07-15

申请人： ORIC Pharmaceuticals, Inc.

发明人： Xiaohui DU ,  John EKSTEROWICZ ,  Valeria R. FANTIN ,  Daqing SUN ,  Qiuping YE ,  Jared MOORE ,  Tatiana ZAVOROTINSKAYA ,  Brian R. BLANK ,  Hiroyuki KAWAI ,  Chien-Hung YEH ,  Yosup REW ,  Kejia WU ,  Johnny PHAM

IPC分类号： A61K31/675 ,  C07F9/6561 ,  A61P35/00 ,  A61K45/06

摘要： Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

公开(公告)号：US20240124512A1

公开(公告)日：2024-04-18

申请号：US18476763

申请日：2023-09-28

申请人： ORIC Pharmaceuticals, Inc.

发明人： Xiaohui DU ,  John EKSTEROWICZ ,  Valeria R. FANTIN ,  Daqing SUN ,  Qiuping YE ,  Jared MOORE ,  Tatiana ZAVOROTINSKAYA ,  Brian R. BLANK ,  Yosup REW ,  Kejia WU ,  Liusheng ZHU ,  Johnny PHAM ,  Hiroyuki KAWAI

IPC分类号： C07H19/23 ,  A61K45/06 ,  C07H19/14

CPC分类号： C07H19/23 ,  A61K45/06 ,  C07H19/14

摘要： Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

公开(公告)号：US20200347090A1

公开(公告)日：2020-11-05

申请号：US16760380

申请日：2018-11-02

申请人： ORIC Pharmaceuticals, Inc.

发明人： Xiaohui DU ,  John EKSTEROWICZ ,  Valeria R. FANTIN ,  Erica L. JACKSON ,  Daqing SUN ,  Qiuping YE ,  Jared MOORE ,  Tatiana ZAVOROTINSKAYA

IPC分类号： C07H19/23

摘要： Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

公开(公告)号：US20220220147A1

公开(公告)日：2022-07-14

申请号：US17697318

申请日：2022-03-17

申请人： ORIC Pharmaceuticals, Inc.

发明人： Xiaohui DU ,  John EKSTEROWICZ ,  Valeria R. FANTIN ,  Daqing SUN ,  Qiuping YE ,  Jared MOORE ,  Tatiana ZAVOROTINSKAYA ,  Brian R. BLANK ,  Yosup REW ,  Kejia WU ,  Liusheng ZHU ,  Johnny PHAM ,  Hiroyuki KAWAI

IPC分类号： C07H19/23

摘要： Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

公开(公告)号：US20210130389A1

公开(公告)日：2021-05-06

申请号：US17083871

申请日：2020-10-29

申请人： ORIC Pharmaceuticals, Inc.

发明人： Xiaohui DU ,  John EKSTEROWICZ ,  Valeria R. FANTIN ,  Daqing SUN ,  Qiuping YE ,  Jared MOORE ,  Tatiana ZAVOROTINSKAYA ,  Brian R. BLANK ,  Yosup REW ,  Kejia WU ,  Liusheng ZHU ,  Johnny PHAM ,  Hiroyuki KAWAI ,  Chien-Hung YEH

IPC分类号： C07H19/23 ,  A61P35/00

摘要： Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

公开(公告)号：US20210214387A1

公开(公告)日：2021-07-15

申请号：US17204272

申请日：2021-03-17

申请人： ORIC Pharmaceuticals, Inc.

发明人： Xiaohui DU ,  John EKSTEROWICZ ,  Valeria R. FANTIN ,  Daqing SUN ,  Qiuping YE ,  Jared MOORE ,  Tatiana ZAVOROTINSKAYA ,  Brian R. BLANK ,  Yosup REW ,  Kejia WU ,  Liusheng ZHU ,  Johnny PHAM ,  Hiroyuki KAWAI ,  Chien-Hung YEH

IPC分类号： C07H19/23

摘要： Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

公开(公告)号：US20210130390A1

公开(公告)日：2021-05-06

申请号：US17114993

申请日：2020-12-08

申请人： ORIC Pharmaceuticals, Inc.

发明人： Xiaohui DU ,  John EKSTEROWICZ ,  Valeria R. FANTIN ,  Daqing SUN ,  Qiuping YE ,  Jared MOORE ,  Tatiana ZAVOROTINSKAYA ,  Brian R. BLANK ,  Yosup REW ,  Kejia WU ,  Liusheng ZHU ,  Johnny PHAM ,  Hiroyuki KAWAI ,  Chien-Hung YEH

IPC分类号： C07H19/23

摘要： Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

公开(公告)号：US20230131747A1

公开(公告)日：2023-04-27

申请号：US18051125

申请日：2022-10-31

申请人： ORIC Pharmaceuticals, Inc.

发明人： Xiaohui DU ,  John EKSTEROWICZ ,  Valeria R. FANTIN ,  Daqing SUN ,  Qiuping YE ,  Jared MOORE ,  Tatiana ZAVOROTINSKAYA ,  Brian R. BLANK ,  Yosup REW ,  Kejia WU ,  Liusheng ZHU ,  Johnny PHAM ,  Hiroyuki KAWAI ,  Chien-Hung YEH

IPC分类号： C07H19/23 ,  A61P35/00

摘要： Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

公开(公告)号：US20220411459A1

公开(公告)日：2022-12-29

申请号：US17771711

申请日：2020-10-29

申请人： ORIC Pharmaceuticals, Inc.

发明人： Xiaohui DU ,  John EKSTEROWICZ ,  Valeria R. FANTIN ,  Daqing SUN ,  Qiuping YE ,  Jared MOORE ,  Tatiana ZAVOROTINSKAYA ,  Brian R. BLANK ,  Yosup REW ,  Kejia WU ,  Liusheng ZHU ,  Johnny PHAM ,  Hiroyuki KAWAI ,  Chien-Hung YEH

IPC分类号： C07H19/23 ,  A61K45/06

摘要： Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

公开(公告)号：US20220259253A1

公开(公告)日：2022-08-18

申请号：US17722513

申请日：2022-04-18

申请人： ORIC Pharmaceuticals, Inc.

发明人： Xiaohui DU ,  John EKSTEROWICZ ,  Valeria R. FANTIN ,  Erica L. JACKSON ,  Daqing SUN ,  Qiuping YE ,  Jared MOORE ,  Tatiana ZAVOROTINSKAYA

IPC分类号： C07H19/23 ,  A61P35/00 ,  A61K31/706 ,  C07H19/056 ,  A61K31/7064

摘要： Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.