公开(公告)号：US11795056B2

公开(公告)日：2023-10-24

申请号：US16770403

申请日：2018-12-07

Applicant: OSAKA UNIVERSITY

Inventor： Atsushi Shinohara ,  Atsushi Toyoshima ,  Takashi Yoshimura ,  Akimitsu Kanda

IPC: C01B7/00 ,  G21G1/00

CPC classification number: C01B7/00 ,  G21G1/001 ,  C01B2210/0009 ,  G21G2001/0094

Abstract: Provided is a method capable of separating and purifying astatine-211 in a high yield and dissolving same in a solution. A method for producing astatine-211, including a step of irradiating α ray to bismuth to produce astatine-211 in the bismuth, and a step of distilling the bismuth that received α ray irradiation with a carrier gas containing an inert gas, O2 and H2O to separate and purify astatine-211, and dissolving the astatine-211 in a solution.

公开(公告)号：US11684683B2

公开(公告)日：2023-06-27

申请号：US16958147

申请日：2018-12-28

Applicant: OSAKA UNIVERSITY

Inventor： Yoshifumi Shirakami ,  Tadashi Watabe ,  Kazuko Kaneda ,  Eku Shimosegawa ,  Atsushi Shinohara ,  Jun Hatazawa

IPC: A61K51/12 ,  A61K47/22

CPC classification number: A61K51/121 ,  A61K47/22

Abstract: The invention provides a method for producing a solution containing 211At− (astatide ion) at a high radiochemical purity by using 211At obtained by a nuclear reaction as a starting material, including a step of adding a reducing agent to a solution containing an impurity derived from 211At. The invention also provides a solution containing 211At− (astatide ion) at a radiochemical purity of not less than 30%.