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    IMAGE ANALYSIS METHOD, STORAGE MEDIUM, IMAGE ANALYSIS DEVICE, AND IMAGE ANALYSIS SYSTEM
    1.
    发明申请
    IMAGE ANALYSIS METHOD, STORAGE MEDIUM, IMAGE ANALYSIS DEVICE, AND IMAGE ANALYSIS SYSTEM 有权

    公开(公告)号：US20220156927A1

    公开(公告)日：2022-05-19

    申请号：US17442499

    申请日：2020-02-12

    Applicant: OSAKA UNIVERSITY

    Inventor： Kazuaki NAKANE ,  Hirofumi YAMAMOTO ,  Sachiko NANKUMO ,  Yasuyoshi TSUTSUMI

    IPC: G06T7/00 ,  G16H30/40 ,  G16H50/80

    Abstract: By analyzing an image of a cell sample, whether a cell shown in the image is cancerous or not, the type of cancer, etc. are objectively and appropriately determined. An image analyzing device (1) includes: a binarizing section (41) which carries out a binarizing process a plurality of times with respect to a single captured image so as to generate a plurality of binarized images, the binarizing section carrying out the binarizing process each time the binarizing section varies a binarization reference value; a Betti number calculating section (42) which calculates a region number, which indicates the number of hole-shaped regions, with respect to each of the plurality of binarized images which have been generated; and a cancer determining section (43) which determines a type of cancer occurring in a cell included in tissue, on the basis of the binarization reference value which has been applied at a time of generation of one of the plurality of binarized images with respect to which one the region number has a given value.

    IMAGE ANALYSIS METHOD, IMAGE ANALYSIS DEVICE, IMAGE ANALYSIS SYSTEM, AND STORAGE MEDIUM
    2.
    发明申请
    IMAGE ANALYSIS METHOD, IMAGE ANALYSIS DEVICE, IMAGE ANALYSIS SYSTEM, AND STORAGE MEDIUM 审中-公开

    公开(公告)号：US20200372649A1

    公开(公告)日：2020-11-26

    申请号：US16766333

    申请日：2018-11-05

    Applicant: OSAKA UNIVERSITY

    Inventor： Kazuaki NAKANE ,  Hirofumi YAMAMOTO ,  Mizuho NISHIO

    IPC: G06T7/00 ,  G06T7/136 ,  G06T7/187 ,  G06T7/11

    Abstract: In order to assess, with high accuracy, a degree of a change having occurred in a structure, the present invention includes: a Betti number calculating section (42) configured to (I) generate, with respect to a single captured image obtained by capturing an image of a structure, a plurality of binarized images having respective binarization reference values different from each other and (II) calculate, for each of the plurality of binarized images, a first characteristic numerical value indicative of the number of connected regions each of which is obtained by connecting pixels each having one of pixel values obtained by binarization; and a prediction score determining section (44) configured to determine, in accordance with a result of a comparison, information on a change having occurred in the structure, the comparison having been made between (i) a pattern indicative of a relationship between (a) the respective binarization reference values and (b) the first characteristic numerical value and (ii) a predetermined reference pattern.

    MUSCULAR FUNCTION IMPROVING AGENT FOR SKELETAL MUSCLE OF WHICH FUNCTION IS DEGRADED DUE TO AGING
    6.
    发明公开
    MUSCULAR FUNCTION IMPROVING AGENT FOR SKELETAL MUSCLE OF WHICH FUNCTION IS DEGRADED DUE TO AGING 审中-公开

    公开(公告)号：US20230381275A1

    公开(公告)日：2023-11-30

    申请号：US18033452

    申请日：2021-10-22

    Applicant: OSAKA UNIVERSITY

    Inventor： Susumu TANAKA ,  Yoshinosuke HAMADA ,  Mikihiko KOGO ,  Hirofumi YAMAMOTO ,  Naomasa KAWAGUCHI

    IPC: A61K38/19 ,  A61K38/08 ,  A61P21/00

    CPC classification number: A61K38/19 ,  A61K38/08 ,  A61P21/00

    Abstract: [Problem] The present invention addresses the problem of providing a muscle function-improving agent for suppressing or improving the decline of muscular functions due to aging. [Solution] Provided is a muscle function-improving agent for suppressing or improving the functional decline of skeletal muscle due to aging, the muscle function-improving agent containing, as an active ingredient, at least one peptide selected from among the following (1)-(3), or a salt thereof: (1) a peptide consisting of the amino acid sequence represented by SEC) ID NO: 1; (2) a peptide which is the fragment of human osteopontin, and in which the C-terminal amino acid sequence is the amino acid sequence represented by SEQ ID NO: 1; and (3) a peptide which consists of an amino acid sequence obtained by substituting, adding, or deleting one or more amino acids in the amino acid sequence of the peptide in (1) or (2), and has the action of suppressing or ameliorating the functional decline of skeletal muscle due to aging.

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