公开(公告)号：US11623198B2

公开(公告)日：2023-04-11

申请号：US16627086

申请日：2018-04-19

Applicant: OSAKA UNIVERSITY ,  CORONA ELECTRIC Co., Ltd.

Inventor： Yuji Goto ,  Hirotsugu Ogi ,  Masatomo So ,  Kensuke Ikenaka ,  Hideki Mochizuki ,  Shinichi Hashimoto

IPC: B01J19/10 ,  G01N1/38 ,  H01L41/00 ,  B06B1/02

Abstract: An ultrasound generation member according to an aspect of the present invention includes an ultrasound generation element configured to emit ultrasound in a direction of a target object in one specific container of a plurality of containers. An ultrasound emission device according to an aspect of the present invention includes the ultrasound generation member, and a drive power supply configured to apply voltage across the ultrasound generation element of the ultrasound generation member. An ultrasound emission device according to an aspect of the present invention includes the ultrasound generation member that includes, as the ultrasound generation element, a plurality of ultrasound generation elements, and a drive power supply configured to apply voltage across the plurality of ultrasound generation elements of the ultrasound generation member.

公开(公告)号：US12099070B2

公开(公告)日：2024-09-24

申请号：US17425197

申请日：2020-02-03

Applicant: Osaka University

Inventor： Kensuke Ikenaka ,  Hideki Mochizuki ,  Cesar Aguirre Martinez ,  Yuji Goto ,  Masatomo So ,  Keita Kakuda ,  Hirotsugu Ogi ,  Kentaro Noi

IPC: G01N33/68 ,  G01N33/58

CPC classification number: G01N33/6896 ,  G01N33/582 ,  G01N33/6845 ,  G01N2333/47 ,  G01N2800/2835

Abstract: A method for discriminating between Parkinson's disease and multiple system atrophy, the method comprising the steps of: (1) preparing a solution containing α-synuclein monomers having a tendency to produce rod-like aggregates and/or a solution containing α-synuclein monomers having a tendency to produce twisted aggregates; (2) adding a biological sample from a subject to the solution(s) containing the α-synuclein monomers prepared in step (1); (3) allowing the α-synuclein monomers to aggregate in the solution(s) obtained in step (2); and (4) detecting α-synuclein aggregates formed in step (3).

公开(公告)号：US20220128576A1

公开(公告)日：2022-04-28

申请号：US17425197

申请日：2020-02-03

Applicant: Osaka University

Inventor： Kensuke Ikenaka ,  Hideki Mochizuki ,  Cesar Aguirre Martinez ,  Yuji Goto ,  Masatomo So ,  Keita Kakuda ,  Hirotsugu Ogi ,  Kentaro Noi

IPC: G01N33/68 ,  G01N33/58

Abstract: A method for discriminating between Parkinson's disease and multiple system atrophy, the method comprising the steps of: (1) preparing a solution containing α-synuclein monomers having a tendency to produce rod-like aggregates and/or a solution containing α-synuclein monomers having a tendency to produce twisted aggregates; (2) adding a biological sample from a subject to the solution(s) containing the α-synuclein monomers prepared in step (1); (3) allowing the α-synuclein monomers to aggregate in the solution(s) obtained in step (2); and (4) detecting α-synuclein aggregates formed in step (3).