公开(公告)号：US20170368333A1

公开(公告)日：2017-12-28

申请号：US15700935

申请日：2017-09-11

Applicant: Oculeve, Inc.

Inventor： James Donald LOUDIN ,  Amitava GUPTA ,  John WARDLE ,  Christopher William STIVERS ,  Anand DORAISWAMY ,  Marie Dvorak CHRIST ,  F. Richard CHRIST

IPC: A61N1/05 ,  C08F230/08 ,  H01B1/12 ,  C08F220/54 ,  A61N1/04 ,  A61N1/36

CPC classification number: A61N1/0546 ,  A61N1/0456 ,  A61N1/0496 ,  A61N1/36014 ,  C08F220/54 ,  C08F230/08 ,  H01B1/125 ,  Y10T29/49826 ,  Y10T29/49885 ,  C08F226/10 ,  C08F220/20 ,  C08F2222/1013 ,  C08F2230/085

Abstract: Described herein are polymer formulations for facilitating electrical stimulation of nasal or sinus tissue. The polymer formulations may be hydrogels that are prepared by a UV cross-linking process. The hydrogels may be included as a component of nasal stimulator devices that electrically stimulate the lacrimal gland to improve tear production and treat dry eye. Additionally, devices and methods for manufacturing the nasal stimulators, including shaping of the hydrogel, are described herein.

公开(公告)号：US20180280688A1

公开(公告)日：2018-10-04

申请号：US15904036

申请日：2018-02-23

Applicant: Oculeve, Inc.

Inventor： James Donald LOUDIN ,  Amitava GUPTA ,  John WARDLE ,  Christopher William STIVERS ,  Anand DORAISWAMY ,  Marie Dvorak CHRIST ,  F. Richard CHRIST

IPC: A61N1/05 ,  H01B1/12 ,  C08F220/54 ,  C08F220/20 ,  C08F226/10 ,  C08F230/08 ,  A61N1/04 ,  A61N1/36 ,  C08F222/10

Abstract: Described herein are polymer formulations for facilitating electrical stimulation of nasal or sinus tissue. The polymer formulations may be hydrogels that are prepared by a UV cross-linking process. The hydrogels may be included as a component of nasal stimulator devices that electrically stimulate the lacrimal gland to improve tear production and treat dry eye. Additionally, devices and methods for manufacturing the nasal stimulators, including shaping of the hydrogel, are described herein.

公开(公告)号：US20150238754A1

公开(公告)日：2015-08-27

申请号：US14630471

申请日：2015-02-24

Applicant: Oculeve, Inc.

Inventor： James Donald LOUDIN ,  Amitava GUPTA ,  John WARDLE ,  Christopher William STIVERS ,  Anand DORAISWAMY ,  Marie Dvorak CHRIST ,  F. Richard CHRIST

IPC: A61N1/05 ,  H01B13/00 ,  A61N1/36 ,  H01B1/12

CPC classification number: A61N1/0546 ,  A61N1/0456 ,  A61N1/0496 ,  A61N1/36014 ,  C08F220/54 ,  C08F230/08 ,  H01B1/125 ,  Y10T29/49826 ,  Y10T29/49885 ,  C08F226/10 ,  C08F220/20 ,  C08F2222/1013 ,  C08F2230/085

Abstract: Described herein are polymer formulations for facilitating electrical stimulation of nasal or sinus tissue. The polymer formulations may be hydrogels that are prepared by a UV cross-linking process. The hydrogels may be included as a component of nasal stimulator devices that electrically stimulate the lacrimal gland to improve tear production and treat dry eye. Additionally, devices and methods for manufacturing the nasal stimulators, including shaping of the hydrogel, are described herein.

Abstract translation: 本文描述的是用于促进鼻或鼻窦组织的电刺激的聚合物制剂。 聚合物制剂可以是通过UV交联方法制备的水凝胶。 可以将水凝胶作为鼻刺激装置的组分包含，以刺激泪腺以改善泪液的产生并治疗干眼症。 此外，本文描述了用于制造鼻刺激器的装置和方法，包括水凝胶的成形。