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公开(公告)号:US06685950B2
公开(公告)日:2004-02-03
申请号:US09903013
申请日:2001-07-11
申请人: Olaf Weber , Tobias Schlapp , Angela Siegling , Andreas Knorr , Claudia Hirth-Dietrich , Gudrun Theiss
发明人: Olaf Weber , Tobias Schlapp , Angela Siegling , Andreas Knorr , Claudia Hirth-Dietrich , Gudrun Theiss
IPC分类号: A61K4500
CPC分类号: A61K35/76 , C12N2710/24232
摘要: The present invention relates to the use of strains of Parapoxvirus ovis as immunotherapeutic agents for immunodeficiencies of an infectious or non-infectious nature, and to the use of strains of Parapoxvirus ovis for treating tumor diseases and viral infections, and diseases which accompany them, and the use of strains of Parapoxvirus ovis for producing medicaments for use in humans and animals.
摘要翻译: 本发明涉及副作用病毒ovis菌株作为感染性或非感染性免疫缺陷的免疫治疗剂的用途,以及使用Parapoxvirus ovis菌株治疗肿瘤疾病和病毒感染以及伴随它们的疾病的用途,以及 使用副毒素病毒ovis菌株生产用于人和动物的药物。
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公开(公告)号:US06632647B2
公开(公告)日:2003-10-14
申请号:US09903005
申请日:2001-07-11
申请人: Claudia Hirth-Dietrich , Tobias Schlapp , Angela Siegling , Andreas Knorr , Olaf Weber , Gudrun Theiss
发明人: Claudia Hirth-Dietrich , Tobias Schlapp , Angela Siegling , Andreas Knorr , Olaf Weber , Gudrun Theiss
IPC分类号: C12N708
CPC分类号: A61K35/76 , A61K2039/5252 , C12N2710/24232
摘要: The present invention relates to the use, in humans, of inactivated parapoxviruses for the prophylaxis and treatment of diseases which are accompanied by an increased deposition of collagen, with it being possible for both internal organs, such as the liver, and the skin and its appended structures, to be affected. The invention relates, in particular, to liver fibrosis and/or liver cirrhosis consequent upon virus hepatitis, or to ethanol-induced liver diseases and to cystic fibrosis.
摘要翻译: 本发明涉及在人类中用于预防和治疗伴随着胶原蛋白沉积增加的疾病的灭活的副代谢病毒,其中内脏器官例如肝脏和皮肤以及它们的可能性 附加结构,受影响。 本发明特别涉及由于病毒性肝炎引起的肝纤维化和/或肝硬化,或乙醇诱导的肝脏疾病和囊性纤维化。
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