公开(公告)号：US5808076A

公开(公告)日：1998-09-15

申请号：US761687

申请日：1996-12-06

申请人： Oliver Vetter ,  Reinhold Lohr ,  Matthias Kuhn ,  Hubert Rast ,  Martin Scheer ,  Ernst Heinen ,  Francisco Cabrera

发明人： Oliver Vetter ,  Reinhold Lohr ,  Matthias Kuhn ,  Hubert Rast ,  Martin Scheer ,  Ernst Heinen ,  Francisco Cabrera

IPC分类号： A61K31/47 ,  A61K31/19 ,  A61K31/194 ,  A61K31/4375 ,  A61K31/495 ,  A61K31/496 ,  A61P33/00 ,  C07D215/16

CPC分类号： A61K31/496

摘要： The present invention relates to the preparation of orally administrable formulations of quinolone- or naphthyridonecarboxylic acids by mixing quinolone- or naphthyridonecarboxylic acids as such or in the form of their water-soluble salts or derivatives, preferably in the form of their aqueous salt solutions, with embonic acid as such or in the form of its water-soluble salts or derivatives, preferably in the form of its aqueous salt solutions, in the presence of an excipient, optionally in the presence of auxiliaries, when using dry mixtures in the presence of water, and optionally converting the mixture obtained into further ready-to-use forms.

摘要翻译： 本发明涉及通过将喹诺酮或萘啶酮羧酸本身混合或以其水溶性盐或衍生物的形式，优选以其盐水溶液的形式，通过混合喹诺酮或萘啶酮羧酸的口服给药制剂， 或者以其水溶性盐或衍生物的形式，优选以其盐水溶液的形式，在赋形剂存在下，任选地在助剂的存在下，当在水存在下使用干混合物时， ，并且任选地将所获得的混合物转化成另外的即用形式。

公开(公告)号：US20060121095A1

公开(公告)日：2006-06-08

申请号：US11333450

申请日：2006-01-17

申请人： Gordon Huber ,  David Jones ,  John Kuenzi ,  Kevin Kuenzi ,  Francisco Cabrera

发明人： Gordon Huber ,  David Jones ,  John Kuenzi ,  Kevin Kuenzi ,  Francisco Cabrera

IPC分类号： A23K1/165 ,  A23K1/00

CPC分类号： A23K50/48 ,  A23K20/10 ,  A23K20/168 ,  A23K40/20 ,  A23K40/25 ,  A23K50/42 ,  A23K50/45

摘要： Improved extrusion-processed daily ration animal feeds are provided which include minor amounts of actives to ensure that an animal consuming the feed receives quantities of the actives sufficient to establish and maintain substantially constant concentrations of the actives in the animal's bloodstream. The feeds may be produced by extrusion with addition of minor quantities of one or more actives so as to uniformly distribute the actives throughout the extruded product.

公开(公告)号：US07112336B2

公开(公告)日：2006-09-26

申请号：US10835804

申请日：2004-04-30

申请人： Francisco Cabrera

发明人： Francisco Cabrera

IPC分类号： A61K47/00 ,  A61K9/14 ,  A23K1/165

CPC分类号： A61K31/4995 ,  A23K20/10 ,  A23K20/111 ,  A23K40/10 ,  A61K9/146 ,  A61K31/4375 ,  A61K31/47 ,  A61K31/497

摘要： The present invention relates to a solid dispersion of quinolone- or naphthyridonecarboxylic acids in an insoluble matrix representative of a shellac, and methods preparing and using the same in masking the taste and improving the uptake by animals.

摘要翻译： 本发明涉及喹诺酮或萘啶酮羧酸在代表虫胶的不溶性基质中的固体分散体，以及制备和使用其来掩盖味道并改善动物摄取的方法。

公开(公告)号：US5213800A

公开(公告)日：1993-05-25

申请号：US470295

申请日：1990-01-25

申请人： Francisco Cabrera

发明人： Francisco Cabrera

IPC分类号： A01N25/26 ,  A01N47/44

CPC分类号： A01N25/26 ,  A01N47/44

摘要： Flowable, highly water soluble discrete particle disinfecting composition of chlorhexidine are provided. The composition is powdery in nature and makes chlorhexidine suitable for a general use, all purpose disinfectant for veterinary uses. It is comprised of a substrate of polyhydric alcohol coated with an encapsulating effective amount of a compatible surfactant, followed by a thin disinfecting coating of chlorhexidine.

摘要翻译： 提供可洗涤，高水溶性离散颗粒消毒组合物洗必泰。 组合物本质上是粉状的，并且使氯己定适合一般用途，用于兽用用途的各种消毒剂。 它由多层醇的底物组成，其中涂有有效量的相容性表面活性剂，随后用洗必泰薄消毒涂层。