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公开(公告)号：US11739123B2
公开(公告)日：2023-08-29
申请号：US17340731
申请日：2021-06-07
Applicant: OnKure, Inc.
Inventor： Anthony D. Piscopio , Xiaoyong Fu , Feng Shi , Huayan Liu , Zhifeng Li
IPC: C07K1/113 , C07K11/02 , C07K5/097 , C07D498/06 , C07D513/06 , C07D513/14 , C07K11/00 , A61K38/15 , C07K1/107
CPC classification number: C07K11/02 , A61K38/15 , C07D498/06 , C07D513/06 , C07D513/14 , C07K1/1077 , C07K1/113 , C07K5/0821 , C07K11/00
Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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公开(公告)号：US20240116989A1
公开(公告)日：2024-04-11
申请号：US18222170
申请日：2023-07-14
Applicant: OnKure, Inc.
Inventor： Anthony D. Piscopio , Xiaoyong Fu , Feng Shi , Huayan Liu , Zhifeng Li
IPC: C07K11/02 , A61K38/15 , C07D498/06 , C07D513/06 , C07D513/14 , C07K1/107 , C07K1/113 , C07K5/097 , C07K11/00
CPC classification number: C07K11/02 , A61K38/15 , C07D498/06 , C07D513/06 , C07D513/14 , C07K1/1077 , C07K1/113 , C07K5/0821 , C07K11/00
Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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公开(公告)号：US20190177372A1
公开(公告)日：2019-06-13
申请号：US16127399
申请日：2018-09-11
Applicant: ONKURE, INC.
Inventor： Anthony D. Piscopio , Xiaoyong Fu , Feng Shi , Huayan Liu , Zhifeng Li
IPC: C07K11/02 , C07D513/14 , C07D513/06 , C07K5/097 , C07K1/113 , C07D498/06
Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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公开(公告)号：US11053284B2
公开(公告)日：2021-07-06
申请号：US16781233
申请日：2020-02-04
Applicant: ONKURE, INC.
Inventor： Anthony D. Piscopio , Xiaoyong Fu , Feng Shi , Huayan Liu , Zhifeng Li
IPC: A61K38/15 , C07K11/00 , C07K11/02 , C07K5/097 , C07D498/06 , C07D513/06 , C07D513/14 , C07K1/113
Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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公开(公告)号：US20200347097A1
公开(公告)日：2020-11-05
申请号：US16781233
申请日：2020-02-04
Applicant: ONKURE, INC.
Inventor： Anthony D. Piscopio , Xiaoyong Fu , Feng Shi , Huayan Liu , Zhifeng Li
IPC: C07K11/02 , C07K5/097 , C07D498/06 , C07D513/06 , C07D513/14 , C07K11/00 , A61K38/15 , C07K1/113
Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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Patent Agency Ranking
公开(公告)号：US12252511B2
公开(公告)日：2025-03-18
申请号：US18222170
申请日：2023-07-14
Applicant: OnKure, Inc.
Inventor： Anthony D. Piscopio , Xiaoyong Fu , Feng Shi , Huayan Liu , Zhifeng Li
IPC: C07K1/113 , A61K38/15 , C07D498/06 , C07D513/06 , C07D513/14 , C07K1/107 , C07K5/097 , C07K11/00 , C07K11/02
Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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公开(公告)号：US20220002347A1
公开(公告)日：2022-01-06
申请号：US17340731
申请日：2021-06-07
Applicant: ONKURE, INC.
Inventor： Anthony D. Piscopio , Xiaoyong Fu , Feng Shi , Huayan Liu , Zhifeng Li
IPC: C07K11/02 , C07K5/097 , C07D498/06 , C07D513/06 , C07D513/14 , C07K11/00 , A61K38/15 , C07K1/113
Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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公开(公告)号：US10689419B2
公开(公告)日：2020-06-23
申请号：US16127399
申请日：2018-09-11
Applicant: ONKURE, INC.
Inventor： Anthony D. Piscopio , Xiaoyong Fu , Feng Shi , Huayan Liu , Zhifeng Li
IPC: A61K38/15 , C07K11/00 , C07K11/02 , C07K5/097 , C07D498/06 , C07D513/06 , C07D513/14 , C07K1/113
Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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公开(公告)号：US10100089B2
公开(公告)日：2018-10-16
申请号：US15313800
申请日：2015-05-27
Applicant: ONKURE, INC.
Inventor： Anthony D. Piscopio , Xiaoyong Fu , Feng Shi , Huayan Liu , Zhifeng Li
Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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公开(公告)号：US20170183382A1
公开(公告)日：2017-06-29
申请号：US15313800
申请日：2015-05-27
Applicant: ONKURE, INC.
Inventor： Anthony D. Piscopio , Xiaoyong Fu , Feng Shi , Huayan Liu , Zhifeng Li
IPC: C07K11/02
CPC classification number: C07K11/02 , C07D498/06 , C07D513/06 , C07D513/14 , C07K1/113 , C07K5/0821
Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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