公开(公告)号：US11594005B2

公开(公告)日：2023-02-28

申请号：US16755173

申请日：2018-10-15

Applicant: Optellum Limited

Inventor： Jerome Declerck ,  Timor Kadir

IPC: G06V10/28 ,  G16H30/20 ,  G06K9/62 ,  G06T7/11 ,  G06F17/18 ,  G06T7/00 ,  G06V10/44 ,  G06V10/46 ,  G06N3/08

Abstract: A quantification system (700) is described that includes: at least one input (710) configured to provide two input medical images and two locations of interest in said input medical images that correspond to a same anatomical region; and a mapping circuit (725) configured to compute a direct quantification of change of said input medical images from the at least one input (710).

公开(公告)号：US11055559B1

公开(公告)日：2021-07-06

申请号：US16755171

申请日：2018-10-15

Applicant: Optellum Limited

Inventor： Jerome Declerck ,  Timor Kadir

IPC: G06K9/38 ,  G06K9/62 ,  G16H30/20 ,  G06K9/46

Abstract: A quantification system (300) is described that includes: at least one input (310) configured to provide at least one input medical image and provide a location of interest in the at least one input medical image; and a mapping circuit (325). The mapping circuit (325) is configured to: compute a direct quantification result from the location of interest of the at least one input medical image to a quantification of interest and output a direct first quantification result therefrom; generate a saliency map as part of the computation of the direct quantification result; and derive a segmentation from the saliency map, such that the segmentation independently generates a second quantification result that is within a result range of the direct first quantification result.

公开(公告)号：US20230298177A1

公开(公告)日：2023-09-21

申请号：US17696802

申请日：2022-03-16

Applicant: Optellum Limited

Inventor： Carlos Arteta ,  Jerome Declerck

IPC: G06T7/00

CPC classification number: G06T7/0014 ,  G06T2207/30064 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/10081

Abstract: A CADx system for analysing medical images to monitor at least one feature on the image to predict at least one of a change of the state or maintenance of the current state of a monitored feature within a time frame is described. The system comprising: an input circuit for receiving at least one medical input image; a feature state change circuit for analysing the received input image and predicting a state change comprising: a state change predictor to predict a state change of the monitored feature within the time frame; and an output circuit to output an indication of the change of state or maintenance of the current state of the monitored feature within the time frame based on the prediction of the feature state change predictor. A method of training a feature state change prediction circuit using Machine Learning is also described.

公开(公告)号：US11704792B2

公开(公告)日：2023-07-18

申请号：US16645872

申请日：2018-09-24

Applicant: Optellum Limited ,  Timor Kadir ,  Lyndsey Pickup ,  Vaclav Potesil ,  Jerome Declerck

Inventor： Timor Kadir ,  Lyndsey Pickup ,  Vaclav Potesil ,  Jerome Declerck

IPC: G06K9/00 ,  G06T7/00 ,  G16H50/30 ,  G16H50/70 ,  G16H50/20 ,  G16H30/40

CPC classification number: G06T7/0012 ,  G16H30/40 ,  G16H50/20 ,  G16H50/30 ,  G16H50/70 ,  G06T2207/10081 ,  G06T2207/10104 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30064

Abstract: A Computer Aided Diagnosis, CADx, system (200) is described that comprises: at least one input (210, 212, 214) configured to provide at least one input medical image; and a CADx processing engine (220) configured to receive and process the at least one input medical image and produce at least one CADx score. A CADx score mapping circuit is operably coupled to the CADx processing engine (220) and configured to: map the at least one CADx score to a risk adjusted virtual score; and generate an output (235) of at least the risk adjusted virtual score associated with the processed at least one input medical image. The at least one CADx score and the risk adjusted virtual score correspond to an equivalent risk of condition or disease associated with a patient.

公开(公告)号：US20210287795A1

公开(公告)日：2021-09-16

申请号：US16816910

申请日：2020-03-12

Applicant: Optellum Limited

Inventor： Jerome Declerck ,  Nicholas Dowson ,  Timor Kadir ,  Vaclav Potesil

IPC: G16H50/20 ,  G16H30/20 ,  G16H70/60 ,  G16H30/40 ,  G16H50/30 ,  G16H50/70 ,  G16H50/50 ,  G16H15/00 ,  G06N3/08 ,  G06N3/04 ,  A61B6/00 ,  A61B6/03

Abstract: A Computer Aided Diagnosis, CAD, lung disease risk measure system is described that comprises: an input circuit configured to receive at least one input medical image of a patient in which the patient's lungs are visible. A smoking history system is operably coupled to the input circuit and configured to receive and analyse the at least one input medical image of a patient and determine an equivalent smoking history of the patient based on the at least one input medical image and output a smoking history parameter based on the determined equivalent smoking history of the patient.

公开(公告)号：US12112852B2

公开(公告)日：2024-10-08

申请号：US17094934

申请日：2020-11-11

Applicant: Optellum Limited

Inventor： Carlos Federico Arteta Montilva ,  Nicholas Dowson ,  Timor Kadir ,  Jerome Declerck

IPC: G16H50/20 ,  G06N3/04 ,  G06T7/00 ,  G16H10/60 ,  G16H30/40 ,  G16H50/30

CPC classification number: G16H50/20 ,  G06N3/04 ,  G06T7/0012 ,  G16H10/60 ,  G16H30/40 ,  G16H50/30 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30061

Abstract: A method for providing a lung disease risk measure in a Computer Aided Diagnosis system is described. The method comprises the steps of: receiving an input comprising at least one input image showing all or part of the lungs of a patient; analysing the input to identify a feature descriptor comprised of at least one feature group, where each feature group comprises at least one feature computed from the input image; calculating a score explanation factor for each feature group, and an overall disease risk score for the patient's risk of lung disease from the feature descriptor; outputting the overall disease score risk score and a corresponding score explanation factor for each feature group. A computer aided diagnosis system is also described, along with a method for training a computer aided diagnosis system.

公开(公告)号：US11955243B2

公开(公告)日：2024-04-09

申请号：US17094949

申请日：2020-11-11

Applicant: Optellum Limited

Inventor： Carlos Federico Arteta Montilva ,  Nicholas Dowson ,  Timor Kadir ,  Jerome Declerck

IPC: G16H50/30 ,  A61B5/00 ,  A61B5/055 ,  A61B5/08 ,  A61B6/03 ,  A61B8/00 ,  G06T7/00 ,  G16H10/40 ,  G16H30/20 ,  G16H30/40 ,  G16H50/20 ,  G16H50/50 ,  G16H50/70

CPC classification number: G16H50/30 ,  A61B5/004 ,  A61B5/055 ,  A61B5/08 ,  A61B5/7264 ,  A61B5/7275 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/746 ,  A61B5/7475 ,  A61B6/032 ,  A61B6/037 ,  A61B8/00 ,  G06T7/0016 ,  G16H10/40 ,  G16H30/20 ,  G16H30/40 ,  G16H50/20 ,  G16H50/50 ,  G16H50/70 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30061

Abstract: A method for providing a lung disease risk measure in a Computer Aided Diagnosis system is described. The method comprising the steps of: receiving a plurality of inputs for a subject, each input comprising at least one image showing all or part of the lungs of a patient and a time stamp for the image, where the inputs are obtained at varying intervals; analysing the inputs to assess temporal changes in the images using at least one of an input data encoder and a time stamp encoder; inputting the output of at least one of the encoders to a score calculator to calculate a risk score; outputting the risk score indicating the lung disease risk for the subject. A Computer Aided diagnosis system for implementing the method is also described.