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公开(公告)号：US11123006B2
公开(公告)日：2021-09-21
申请号：US16752839
申请日：2020-01-27
申请人： Pacesetter, Inc.
发明人： Nima Badie , Jan Mangual-Soto , Luke McSpadden
摘要： Methods and devices are provided that collect intra-cardiac electrogram (EGM) signals over first and second sensing channels (channel-1 and channel-2 EGM signals, respectively) associated with an event of interest that includes a right ventricle (RV) and a left ventricle (LV), determine first, second and third global characteristics (GC) from the channel-1 and channel-2 EGM signals, and define a QRS start time within at least one of the EGM signals; and determine a threshold crossing. The methods and systems compare at least one of the first, second and third GC to the threshold crossing, select one of the first, second and third GC based on the comparing; defining a QRS end time, within at least one of the channel-1 and channel-2 EGM signals based on the one of the first, second and third GC selected, and calculate a QRS duration based on the QRS start time and QRS end time.
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公开(公告)号：US20190192859A1
公开(公告)日：2019-06-27
申请号：US15851372
申请日：2017-12-21
申请人： PACESETTER, INC.
发明人： Nima Badie , Jan Mangual-Soto , Luke McSpadden , Aditya Goil
CPC分类号： A61N1/36514 , A61N1/025 , A61N1/0563 , A61N1/3627 , A61N1/36507 , A61N1/36842 , A61N1/36843 , A61N1/371
摘要： Methods and devices are provided for, under control of one or more processors within an implantable medical device (IMD), delivering cardiac resynchronization therapy (CRT) at one or more pacing sites. The processors obtain cardiac signals, associated with a candidate beat, from multi-site left ventricular (MSLV) electrodes distributed along a left ventricle and analyze the cardiac signals to collect at least one of a MSLV conduction pattern or a MSLV morphology. The processors compare at least one of the MSLV conduction pattern or MSLV morphology to one or more associated templates. The processors then label the candidate beat as a pseudo-fusion beat based on the comparing and adjust the CRT based on the labeling.
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公开(公告)号：US20200147395A1
公开(公告)日：2020-05-14
申请号：US16740547
申请日：2020-01-13
申请人： Pacesetter, Inc.
发明人： Nima Badie , Jan Mangual-Soto , Luke McSpadden , Aditya Goil
摘要： Methods and devices are provided for, under control of one or more processors within an implantable medical device (IMD), delivering cardiac resynchronization therapy (CRT) at one or more pacing sites. The processors obtain cardiac signals, associated with a candidate beat, from multi-site left ventricular (MSLV) electrodes distributed along a left ventricle and analyze the cardiac signals to collect at least one of a MSLV conduction pattern or a MSLV morphology. The processors compare at least one of the MSLV conduction pattern or MSLV morphology to one or more associated templates. The processors then label the candidate beat as a pseudo-fusion beat based on the comparing and adjust the CRT based on the labeling.
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公开(公告)号：US20190076660A1
公开(公告)日：2019-03-14
申请号：US15701209
申请日：2017-09-11
申请人： PACESETTER, INC.
摘要： The present disclosure provides systems and methods for optimizing pacing parameters of a cardiac pacing device implanted in a patient. The systems and methods measure a plurality of hemodynamic responses of the patient. Each hemodynamic response is associated with the cardiac pacing device configured with one candidate pacing parameter set of a plurality of candidate pacing parameter sets. Each candidate pacing parameter set is classified as electrically equivalent to a reference pacing parameter set according to a classification criterion. The systems and methods further identify an optimal hemodynamic response from the plurality of hemodynamic responses, and select a final candidate pacing parameter set corresponding to the optimal hemodynamic response.
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公开(公告)号：US11207525B2
公开(公告)日：2021-12-28
申请号：US16740547
申请日：2020-01-13
申请人： Pacesetter, Inc.
发明人： Nima Badie , Jan Mangual-Soto , Luke McSpadden , Aditya Goil
摘要： Methods and devices are provided for, under control of one or more processors within an implantable medical device (IMD), delivering cardiac resynchronization therapy (CRT) at one or more pacing sites. The processors obtain cardiac signals, associated with a candidate beat, from multi-site left ventricular (MSLV) electrodes distributed along a left ventricle and analyze the cardiac signals to collect at least one of a MSLV conduction pattern or a MSLV morphology. The processors compare at least one of the MSLV conduction pattern or MSLV morphology to one or more associated templates. The processors then label the candidate beat as a pseudo-fusion beat based on the comparing and adjust the CRT based on the labeling.
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公开(公告)号：US10582874B2
公开(公告)日：2020-03-10
申请号：US15851342
申请日：2017-12-21
申请人： PACESETTER, INC.
发明人： Nima Badie , Jan Mangual-Soto , Luke McSpadden
IPC分类号： A61B5/04 , A61B5/0472 , A61B5/07 , A61B5/0402 , A61B5/042 , A61B5/00 , A61B5/0456
摘要： Methods and devices are provided comprising an implantable lead having electrodes configured to be located proximate to a heart, the electrodes defining a sensing vector through a region of interest in the heart. The method and system collect an intra-cardiac electrogram (EGM) signal associated with an event of interest and determining an global amplitude characteristic (GAC) and a global slope characteristic (GSC) from the EGM signal under control of one or more processors within an implantable medical device (IMD). A QRS start time is defined, within the EGM signal, based on the GSC and determining a local amplitude characteristic (LAC) for a segment of the EGM signal within a search window of the GAC under control of one or more processors within an implantable medical device (IMD) A QRS end time is defined, within the EGM signal, based on the LAC; and calculating a QRS duration based on the QRS start time and QRS end time under control of one or more processors within an implantable medical device (IMD).
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公开(公告)号：US20190192002A1
公开(公告)日：2019-06-27
申请号：US15851352
申请日：2017-12-21
申请人： PACESETTER, INC.
CPC分类号： A61B5/0031 , A61B5/15087 , A61B5/6869 , A61B5/6882 , A61B18/1492 , A61N1/057 , A61N1/3627
摘要： The present disclosure provides systems and methods for determining a proposed ablation site in a cardiac chamber. A system includes an implanted device configured to record a plurality of intracardiac electrogram (IEGM) couples, and a mapping and ablation system communicatively coupled to the implanted device. The mapping and ablation system is configured to receive the recorded plurality of IEGM couples from the implanted device, calculate a parameter for each of the plurality of IEGM couples, determine, based on the calculated parameters, an area of origin for each IEGM couple, and determine an intersection between the determined areas of origin, wherein the intersection represents the proposed ablation site in the cardiac chamber.
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公开(公告)号：US20200155029A1
公开(公告)日：2020-05-21
申请号：US16752839
申请日：2020-01-27
申请人： Pacesetter, Inc.
发明人： Nima Badie , Jan Mangual-Soto , Luke McSpadden
IPC分类号： A61B5/0472 , A61N1/368 , A61B5/0456
摘要： Methods and devices are provided that collect intra-cardiac electrogram (EGM) signals over first and second sensing channels (channel-1 and channel-2 EGM signals, respectively) associated with an event of interest that includes a right ventricle (RV) and a left ventricle (LV), determine first, second and third global characteristics (GC) from the channel-1 and channel-2 EGM signals, and define a QRS start time within at least one of the EGM signals; and determine a threshold crossing. The methods and systems compare at least one of the first, second and third GC to the threshold crossing, select one of the first, second and third GC based on the comparing; defining a QRS end time, within at least one of the channel-1 and channel-2 EGM signals based on the one of the first, second and third GC selected, and calculate a QRS duration based on the QRS start time and QRS end time.
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公开(公告)号：US10569091B2
公开(公告)日：2020-02-25
申请号：US15851372
申请日：2017-12-21
申请人： PACESETTER, INC.
发明人： Nima Badie , Jan Mangual-Soto , Luke McSpadden , Aditya Goil
摘要： Methods and devices are provided for, under control of one or more processors within an implantable medical device (IMD), delivering cardiac resynchronization therapy (CRT) at one or more pacing sites. The processors obtain cardiac signals, associated with a candidate beat, from multi-site left ventricular (MSLV) electrodes distributed along a left ventricle and analyze the cardiac signals to collect at least one of a MSLV conduction pattern or a MSLV morphology. The processors compare at least one of the MSLV conduction pattern or MSLV morphology to one or more associated templates. The processors then label the candidate beat as a pseudo-fusion beat based on the comparing and adjust the CRT based on the labeling.
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公开(公告)号：US20190192028A1
公开(公告)日：2019-06-27
申请号：US15851342
申请日：2017-12-21
申请人： PACESETTER, INC.
发明人： Nima Badie , Jan Mangual-Soto , Luke McSpadden
IPC分类号： A61B5/0472 , A61B5/04
CPC分类号： A61B5/0472 , A61B5/04004 , A61B5/04012 , A61B5/04021 , A61B5/0422 , A61B5/0456 , A61B5/076 , A61B5/6867
摘要： Methods and devices are provided comprising an implantable lead having electrodes configured to be located proximate to a heart, the electrodes defining a sensing vector through a region of interest in the heart. The method and system collect an intra-cardiac electrogram (EGM) signal associated with an event of interest and determining an global amplitude characteristic (GAC) and a global slope characteristic (GSC) from the EGM signal under control of one or more processors within an implantable medical device (IMD). A QRS start. time is defined, within the EGM signal, based on the GSC and determining a local amplitude characteristic (LAC) for a segment of the EGM signal within a search window of the GAC under control of one or more processors within an implantable medical device (IMD) A QRS end time is defined, within the EGM signal, based on the LAC; and calculating a QRS duration based on the QRS start time and QRS end time under control of one or more processors within an implantable medical device (IMD).
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