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公开(公告)号：US20240181265A1
公开(公告)日：2024-06-06
申请号：US18440703
申请日：2024-02-13
申请人： Pacesetter, Inc.
发明人： Xiaoyi Min , Weiqun Yang , Benjamin T. Persson , Nima Badie , Kyungmoo Ryu , Gabriel Mouchawar
CPC分类号： A61N1/37288 , A61N1/025 , A61N1/36507 , A61N1/3688 , A61N1/3704 , A61N1/3706 , A61N1/3756 , A61N1/056
摘要： Described herein are methods for use with an implantable system including at least an atrial leadless pacemaker (aLP). Also described herein are specific implementations of an aLP, as well as implantable systems including an aLP. In certain embodiments, the aLP senses a signal from which cardiac activity associated with a ventricular chamber can be detected by the aLP itself based on feature(s) of the sensed signal. The aLP monitors the sensed signal for an intrinsic or paced ventricular activation within a ventricular event monitor window. In response to the aLP detecting an intrinsic or paced ventricular activation itself from the sensed signal within the ventricular event monitor window, the aLP resets an atrial escape interval timer that is used by the aLP to time delivery of an atrial pacing pulse if an intrinsic atrial activation is not detected within an atrial escape interval.
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公开(公告)号：US11883178B2
公开(公告)日：2024-01-30
申请号：US17675345
申请日：2022-02-18
申请人： Pacesetter, Inc.
发明人： Fujian Qu , Nima Badie , Jong Gill
摘要： A computer implemented method for detecting arrhythmias in cardiac activity including obtaining far field cardiac activity (CA) signals for a series of beats. For at least a portion of the beats, the one or more processors perform, on a beat by beat basis: a) identifying first and second feature of interests (FOI) from a segment of the CA signal that corresponds to a current beat; and b) classifying the current beat into one of first and second groups. The method also includes designating one of the first and second groups to be a primary group based on a relation between the first and second groups, and for the beats in the primary group, selecting one of the first and second FOIs as the R-wave FOI. The method also includes rejecting an arrhythmia detection based on the P-waves detected.
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公开(公告)号：US11844950B2
公开(公告)日：2023-12-19
申请号：US17449231
申请日：2021-09-28
申请人： Pacesetter, Inc
CPC分类号： A61N1/3682 , A61N1/36592
摘要： A method and device for dynamic device based AV delay adjustment are provided. The method provides electrodes that are configured to be located proximate to an atrial (A) site and a right ventricular (RV) site. The method utilizes one or more processors, in an implantable medical device (IMD), for detecting an atrial paced (Ap) event or atrial sensed (As) event. The method determines a measured AV interval corresponding to an interval between the Ap event or the As event and a ventricular sensed event and calculates a percentage-based (PB) offset based on the measured AV interval. The method automatically dynamically adjusting an AV delay, utilized by the IMD, based on the measured AV interval and the PB offset and manages a pacing therapy, utilized by the IMD, based on the AV delay after the adjusting operation.
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4.发明授权公开(公告)号：US11766207B2
公开(公告)日：2023-09-26
申请号：US17223885
申请日：2021-04-06
申请人： Pacesetter, Inc.
发明人： Nima Badie , Fujian Qu , Jong Gill
CPC分类号： A61B5/352 , A61B5/076 , A61B5/287 , A61B5/686 , A61B5/7203 , G16H50/30 , A61B5/361 , G16H40/67
摘要： Described herein are methods, devices, and systems for improving R-wave detection sensitivity and positive predictive value, and for improving arrhythmia detection accuracy. Certain embodiments involve determining whether to classify a potential R-wave as a false R-wave (or more specifically, an over-sensed P-wave) by determining a measure of magnitude of a first portion of the signal corresponding to a first window following the potential R-wave, determining the measure of magnitude of a second portion of the signal corresponding to a second window following the first window, and classifying the potential R-wave as a false R-wave if the measure of magnitude of the second portion of the signal is at least a specified extent larger (e.g., at least 3 times larger) than the measure of magnitude of the first portion of the signal. Certain embodiments also involve adjusting an R-wave marker for a potential R-wave that is classified as a false R-wave.
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公开(公告)号：US20230263480A1
公开(公告)日：2023-08-24
申请号：US18057508
申请日：2022-11-21
申请人： Pacesetter, Inc.
发明人： Kevin J. Davis , Nima Badie , Jong Gill
CPC分类号： A61B5/7282 , G01P15/18 , A61B5/6847 , A61B5/1118 , A61B2562/0219
摘要： A system for verifying a candidate pathologic episode of a patient is provided that includes an accelerometer configured to be implanted in the patient. The accelerometer is configured to obtain accelerometer data along at least one axis. The system also includes a memory configured to store program instructions, and one or more processors that, when executing the program instructions, are configured to obtain accelerometer data. The one or more processors are also configured to determine a plurality of control three-dimensional point vectors related to the accelerometer data, and obtain a biological signal and identify a candidate pathologic episode based on the biological signal. The one or more processors are also configured to analyze the plurality of control three-dimensional point vectors to identify a physical action experienced by the patient, and verify the candidate pathologic episode based on the physical action.
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公开(公告)号：US20230148938A1
公开(公告)日：2023-05-18
申请号：US17949413
申请日：2022-09-21
申请人： Pacesetter, Inc.
发明人： Jan O. Mangual-Soto , Nima Badie , Wenwen Li , Fady Dawoud
CPC分类号： A61B5/352 , A61B5/29 , A61B5/7221
摘要： Computer implemented methods and implantable medical devices (IMD) are provided that obtain cardiac activity (CA) signals for a cardiac beat and compare the CA signals to a sensitivity level to detect a sensed event. One or more processors are configured to change the sensitivity level, utilized by the sensing circuitry, over the cardiac beat based on an adaptive sensitivity profile. The adaptive sensitivity profile has a maximum sensitivity limit (MSL). The process determines whether a characteristic of interest (COI) from a candidate event satisfies criteria relative to the COI for a collection of prior sensed events, declares the candidate event to be a valid sensed event or a false sensed event based on the determine operation; and adjusts the maximum sensitivity limit based on when the COI from the candidate event satisfies the criteria to provide adaptive sensing of CA signals.
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7.发明申请公开(公告)号：US20230135859A1
公开(公告)日：2023-05-04
申请号：US18146870
申请日：2022-12-27
申请人： Pacesetter, Inc.
发明人： Nima Badie , Fujian Qu , Jong Gill
IPC分类号： A61B5/352 , A61B5/00 , A61B5/0245
摘要： Described herein are methods, devices, and systems that monitor heart rate and/or for arrhythmic episodes based on sensed intervals that can include true R-R intervals as well as over-sensed R-R intervals. True R-R intervals are initially identified from an ordered list of the sensed intervals by comparing individual sensed intervals to a sum of an immediately preceding two intervals, and/or an immediately following two intervals. True R-R intervals are also identified by comparing sensed intervals to a mean or median of durations of sensed intervals already identified as true R-R intervals. Individual intervals in a remaining ordered list of sensed intervals (from which true R-R intervals have been removed) are classified as either a short interval or a long interval, and over-sensed R-R intervals are identified based on the results thereof. Such embodiments can be used, e.g., to reduce the reporting of and/or inappropriate responses to false positive tachycardia detections.
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公开(公告)号：US20220401036A1
公开(公告)日：2022-12-22
申请号：US17723207
申请日：2022-04-18
申请人： Pacesetter, Inc.
发明人： Nima Badie , Wenwen Li , Fujian Qu , Jong Gill
摘要： Described herein are methods, devices and system for determining whether an R-wave detection should be classified as a false R-wave detection due to T-wave oversensing (TWO) or P-wave oversensing (PWO). One such method includes comparing a specific morphological characteristic (e.g., peak amplitude) associated with the R-wave detection to the specific morphological characteristic associated with each R-wave detection in a first set of earlier detected R-wave detections to thereby determine whether first TWO or PWO morphological criteria are met, and in a second set of earlier detected R-wave detections to thereby determine whether second TWO or PWO morphological criteria are met, wherein the second set differs from the first set but may have some overlap with the first set. The method also includes determining whether to classify the R-wave detection as a false R-wave detection, based on whether one of the first or second TWO or PWO morphological criteria are met.
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9.发明申请公开(公告)号：US20220296151A1
公开(公告)日：2022-09-22
申请号：US17832765
申请日：2022-06-06
申请人： Pacesetter, Inc.
摘要： Computer implemented methods, devices and systems for monitoring a trend in heart failure (HF) progression are provided. The method comprises sensing left ventricular (LV) activation events at multiple LV sensing sites along a multi-electrode LV lead. The activation events are generated in response to an intrinsic or paced ventricular event. The method implements program instructions on one or more processors for automatically determining a conduction pattern (CP) across the LV sensing sites based on the LV activation events, identifying morphologies (MP) for cardiac signals associated with the LV activation events and repeating the sensing, determining and identifying operations, at select intervals, to build a CP collection and an MP collection. The method calculates an HF trend based on the CP collection and MP collection and classifies a patient condition based on the HF trend to form an HF assessment.
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公开(公告)号：US11284828B2
公开(公告)日：2022-03-29
申请号：US16991421
申请日：2020-08-12
申请人： Pacesetter, Inc.
发明人： Fujian Qu , Nima Badie , Jong Gill
摘要： A computer implemented method for detecting arrhythmias in cardiac activity including obtaining far field cardiac activity (CA) signals for a series of beats. For at least a portion of the beats, the one or more processors perform, on a beat by beat basis: a) identifying first and second feature of interests (FOI) from a segment of the CA signal that corresponds to a current beat; and b) classifying the current beat into one of first and second groups. The method also includes designating one of the first and second groups to be a primary group based on a relation between the first and second groups, and for the beats in the primary group, selecting one of the first and second FOIs as the R-wave FOI. The method also includes rejecting an arrhythmia detection based on the P-waves detected.
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