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公开(公告)号：US20110312960A1
公开(公告)日：2011-12-22
申请号：US13222072
申请日：2011-08-31
申请人： Pascale Gaillard , Anna Quattropani , Vincent Pomel , Thomas Rueckle , Jasna Klicic , Dennis Church
发明人： Pascale Gaillard , Anna Quattropani , Vincent Pomel , Thomas Rueckle , Jasna Klicic , Dennis Church
IPC分类号： A61K31/498 , C07D413/14 , C07D471/04 , A61K31/5377 , A61P37/00 , A61P29/00 , A61P9/00 , A61P25/28 , A61P31/04 , A61P31/12 , A61P37/08 , A61P11/06 , A61P1/18 , A61P13/12 , A61P7/02 , A61P35/00 , A61P37/06 , A61P15/08 , A61P7/00 , A61P11/00 , A61P17/06 , A61P19/04 , A61P1/00 , A61P25/00 , A61P25/14 , A61P9/10 , A61P9/08 , A61P21/00 , A61P35/04 , C07D241/44
CPC分类号： C07D241/44 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04
摘要： The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
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公开(公告)号：US08071597B2
公开(公告)日：2011-12-06
申请号：US12064284
申请日：2006-08-25
申请人： Pascale Gaillard , Anna Quattropani , Vincent Pomel , Thomas Rueckle , Jasna Klicic , Dennis Church
发明人： Pascale Gaillard , Anna Quattropani , Vincent Pomel , Thomas Rueckle , Jasna Klicic , Dennis Church
IPC分类号： A61K31/50 , A61K31/495 , A01N43/58 , A01N43/60 , C07D241/36
CPC分类号： C07D241/44 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04
摘要： The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
摘要翻译： 本发明涉及式（I）的吡嗪衍生物，特别是用于治疗和/或预防自身免疫疾病和/或炎性疾病，心血管疾病，神经变性疾病，细菌或病毒感染，肾脏疾病，血小板聚集，癌症， 移植，移植排斥或肺部损伤。
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公开(公告)号：US08877757B2
公开(公告)日：2014-11-04
申请号：US13222072
申请日：2011-08-31
申请人： Pascale Gaillard , Anna Quattropani , Vincent Pomel , Thomas Rueckle , Jasna Klicic , Dennis Church
发明人： Pascale Gaillard , Anna Quattropani , Vincent Pomel , Thomas Rueckle , Jasna Klicic , Dennis Church
IPC分类号： A01N43/58 , A01N43/60 , A61K31/50 , A61K31/495 , C07D471/00 , C07D403/12 , C07D405/12 , C07D241/44 , C07D471/04 , C07D407/12 , C07D409/12 , C07D401/12 , C07D417/12 , C07D413/12
CPC分类号： C07D241/44 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04
摘要： The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
摘要翻译： 本发明涉及式（I）的吡嗪衍生物，特别是用于治疗和/或预防自身免疫疾病和/或炎性疾病，心血管疾病，神经变性疾病，细菌或病毒感染，肾脏疾病，血小板聚集，癌症， 移植，移植排斥或肺部损伤。
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公开(公告)号：US20110319410A1
公开(公告)日：2011-12-29
申请号：US13222045
申请日：2011-08-31
申请人： PASCALE GAILLARD , Anna Quattropani , Vincent Pomel , Thomas Rueckle , Jasna Klicic , Dennis Church
发明人： PASCALE GAILLARD , Anna Quattropani , Vincent Pomel , Thomas Rueckle , Jasna Klicic , Dennis Church
IPC分类号： A61K31/498 , A61P19/02 , A61P37/00 , A61P29/00 , A61P1/00 , A61P25/28 , A61P31/04 , A61P31/12 , A61P11/06 , A61P35/00 , A61K31/5377 , A61P9/00
CPC分类号： C07D241/44 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04
摘要： The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
摘要翻译： 本发明涉及式（I）的吡嗪衍生物，特别是用于治疗和/或预防自身免疫疾病和/或炎性疾病，心血管疾病，神经变性疾病，细菌或病毒感染，肾脏疾病，血小板聚集，癌症， 移植，移植排斥或肺部损伤。
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公开(公告)号：US20090082356A1
公开(公告)日：2009-03-26
申请号：US12064284
申请日：2006-08-25
申请人： Pascale Gaillard , Anna Quattropani , Vincent Pomel , Thomas Rueckle , Jasna Klicic , Dennis Church
发明人： Pascale Gaillard , Anna Quattropani , Vincent Pomel , Thomas Rueckle , Jasna Klicic , Dennis Church
IPC分类号： A61K31/498 , C07D239/72 , A61P25/28 , A61P29/00 , A61P1/00
CPC分类号： C07D241/44 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04
摘要： The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
摘要翻译： 本发明涉及式（I）的吡嗪衍生物，特别是用于治疗和/或预防自身免疫疾病和/或炎性疾病，心血管疾病，神经变性疾病，细菌或病毒感染，肾脏疾病，血小板聚集，癌症， 移植，移植排斥或肺部损伤。
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6.发明授权公开(公告)号：US08058289B2
公开(公告)日：2011-11-15
申请号：US12906729
申请日：2010-10-18
申请人： Thomas Rueckle , Anna Quattropani , Vincent Pomel , Jerome Dorbais , David Covini , Alexander Bischoff
发明人： Thomas Rueckle , Anna Quattropani , Vincent Pomel , Jerome Dorbais , David Covini , Alexander Bischoff
IPC分类号： A61K31/4355 , C07D471/04 , A61P29/00 , A61P9/00 , A61P25/28 , A61P31/04 , A61P31/12 , A61P27/14 , A61P37/08 , A61P37/06 , A61P1/18 , A61P1/16 , A61P7/02 , A61P35/00
CPC分类号： C07D471/04 , C07D487/04 , C07D491/04
摘要： The present invention is related to pyridine methylene azolidinone derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
摘要翻译： 本发明涉及式（I）的吡啶亚甲基唑烷酮衍生物，特别是用于治疗和/或预防自身免疫疾病和/或炎性疾病，心血管疾病，神经变性疾病，细菌或病毒感染，肾脏疾病，血小板聚集， 癌症，移植，移植排斥或肺部损伤。
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公开(公告)号：US20110086843A1
公开(公告)日：2011-04-14
申请号：US12952231
申请日：2010-11-23
IPC分类号： A61K31/553 , A61K31/427 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K31/41 , A61P29/00 , A61P31/00 , A61P11/06 , A61P9/00 , A61P25/00 , A61P35/00 , A61P13/12 , A61P37/06
CPC分类号： C07D417/14 , C07D417/04
摘要： The present invention is related to thiazole derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
摘要翻译： 本发明涉及式（I）的噻唑衍生物，特别是用于治疗和/或预防自身免疫疾病和/或炎性疾病，心血管疾病，神经变性疾病，细菌或病毒感染，肾脏疾病，血小板聚集，癌症， 移植，移植排斥或肺部损伤。
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公开(公告)号：US07879888B2
公开(公告)日：2011-02-01
申请号：US11915521
申请日：2006-05-24
IPC分类号： A61K31/426 , A61K31/5377 , C07D277/20 , C07D413/14
CPC分类号： C07D417/14 , C07D417/04
摘要： The present invention is related to thiazole derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
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公开(公告)号：US20090029997A1
公开(公告)日：2009-01-29
申请号：US12159663
申请日：2007-01-22
IPC分类号： A61K31/5377 , C07D417/14 , C07D401/14 , A61K31/454 , A61K31/427 , A61P35/00 , A61P17/06 , A61P19/02 , A61P25/28 , A61K31/4439 , A61K31/496 , C07D277/02
CPC分类号： C07D417/04 , C07D417/14
摘要： The present invention is related to thiazole derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
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10.发明申请公开(公告)号：US20080269227A1
公开(公告)日：2008-10-30
申请号：US11574613
申请日：2005-09-02
申请人： Thomas Rueckle , Anna Quattropani , Vincent Pomel , Jerome Dorbais , David Covini , Alexander Bischoff
发明人： Thomas Rueckle , Anna Quattropani , Vincent Pomel , Jerome Dorbais , David Covini , Alexander Bischoff
IPC分类号： A61K31/519 , A61P37/00 , A61P29/00 , A61P9/00 , A61P25/00 , A61P31/00 , A61K31/4439 , A61K31/4355 , A61P35/00 , C07D471/04 , C07D491/048 , A61K31/4985
CPC分类号： C07D471/04 , C07D487/04 , C07D491/04
摘要： The present invention is related to fused pyridine methylene azolidinone derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
摘要翻译： 本发明涉及式（I）的稠合吡啶亚甲基唑烷酮衍生物，特别是用于治疗和/或预防自身免疫性疾病和/或炎性疾病，心血管疾病，神经变性疾病，细菌或病毒感染，肾脏疾病，血小板聚集 ，癌症，移植，移植排斥或肺部损伤。
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