公开(公告)号：US20230183772A1

公开(公告)日：2023-06-15

申请号：US17920142

申请日：2021-04-20

申请人： PAUL HARTMANN AG

发明人： Hans SMOLA ,  Ana JORGE

IPC分类号： C12Q1/04 ,  G01N33/52

CPC分类号： C12Q1/04 ,  G01N33/521

摘要： The present invention relates to a method for assessing a status of a wound of a patient, comprising the steps of determining a concentration of one or more inflammatory markers selected from glucose and eotaxin-1 in a sample from the wound, wherein the sample comprises or consists of wound fluid and the one or more inflammatory markers may indicate an inflammation within the wound, ii. determining a concentration of one or more bacterial markers in the sample, wherein the one or more bacterial markers may indicate a colonization of the wound with metabolically active bacteria, iii. assessing the status of the wound based on the concentrations of the one or more inflammatory markers and the one or more bacterial markers, wherein the status of the wound is assessed as being inflamed or not inflamed and as being colonized with metabolically active bacteria or not colonized with metabolically active bacteria. This diagnostic method allows a reliable, specific and detailed assessment of the status of the wound.

公开(公告)号：US20230250466A1

公开(公告)日：2023-08-10

申请号：US17920087

申请日：2021-04-22

申请人： PAUL HARTMANN AG

发明人： Hans SMOLA ,  Ana JORGE

IPC分类号： C12Q1/42 ,  C12Q1/37 ,  C12Q1/26 ,  B01L3/00

CPC分类号： C12Q1/42 ,  C12Q1/37 ,  C12Q1/26 ,  B01L3/5023 ,  B01L2300/0825 ,  B01L2300/069

摘要： The present invention relates to a method for assessing a status of a wound of a patient, comprising the steps of i. determining a concentration of one or more inflammatory markers in a sample from the wound, wherein the sample comprises or consists of wound fluid and the one or more inflammatory markers may indicate an inflammation within the wound, ii. determining a concentration of one or more bacterial markers in the sample, wherein the one or more bacterial markers may indicate a colonization of the wound with metabolically active bacteria, iii. assessing the status of the wound based on the concentrations of the one or more inflammatory markers and the one or more bacterial markers, wherein the status of the wound is assessed as being inflamed or not inflamed and as being colonized with metabolically active bacteria or not colonized with metabolically active bacteria. This diagnostic method allows a reliable, specific and detailed assessment of the status of the wound.