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公开(公告)号：US20180155739A1
公开(公告)日：2018-06-07
申请号：US15736369
申请日：2016-06-16
发明人： XU HU , BLISS MARIE KERNODLE , MOLLY MARY MCMAHON , ADANE KASSA , XIPING NIU , JAMES KEVIN PRESNAIL , ALBERT L. LU , NINA RICHTMAN , JONATHAN WILLIAM ROBESON
IPC分类号： C12N15/82 , C12N15/113
CPC分类号： C12N15/8286 , A01N37/46 , A01N63/02 , A01N63/04 , A01N65/00 , C07K14/43536 , C07K14/43563 , C12N15/113 , C12N15/8218 , C12N2310/14 , C12N2310/531 , Y02A40/162
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-53 or 107-254 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest and pest population by insect sterilization (i.e., male and female sterility, reduction of sperm count, egg production and viability) and mating-based sterile insect technique (SIT). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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公开(公告)号：US20210145009A1
公开(公告)日：2021-05-20
申请号：US17157306
申请日：2021-01-25
摘要： Entomopathogenic fungal strains, compositions, and methods of using the strains for reducing overall insect damage.
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公开(公告)号：US20150052643A1
公开(公告)日：2015-02-19
申请号：US14525482
申请日：2014-10-28
发明人： KAREN E. BROGLIE , DAVID CHARLES CERF , RAFAEL HERRMANN , ALBERT L. LU , BRIAN MCGONIGLE , JAMES KEVIN PRESNAIL
IPC分类号： C12N15/82 , A01N57/16 , C12N15/113
CPC分类号： C12N15/8286 , A01N57/16 , A01N65/00 , A01N65/44 , C12N15/113 , C12N15/8218 , C12N2310/14 , C12N2310/531 , Y02A40/162
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Pentatomidae plant pest or a N. viridula, Acrosternum hilare, Piezodorus guildini, and/or Halymorpha halys plant pest, decrease the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 1-292 or 302-304 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Pentatomidae. Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
摘要翻译： 提供了使用沉积元件的方法和组合物，当被害虫摄入时，例如五子科植物害虫或N. viridula，Acrosternum hilare，Piezodorus guildini和/或Halymorpha halys植物害虫，降低靶的表达 序列在害虫中。 在具体实施方案中，靶序列的表达降低控制有害生物，因此方法和组合物能够限制对植物的损害。 本发明提供了SEQ ID NO：1-292或302-304中任一项所述的各种靶多核苷酸或其活性变体和片段，其中目标害虫中一个或多个序列的表达降低控制害虫（ 即具有杀虫活性）。 进一步提供的是沉积元件，当受害虫摄入时，降低靶多肽的水平，从而控制害虫。 在具体实施方案中，害虫是五角科。 还提供了包含本发明的沉默元件或其活性变体或片段的植物，植物部分，细菌和其它宿主细胞。
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公开(公告)号：US20200172918A1
公开(公告)日：2020-06-04
申请号：US16790095
申请日：2020-02-13
发明人： XU HU , JAMES KEVIN PRESNAIL , NINA RICHTMAN , LISA PROCYK
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
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5.发明申请公开(公告)号：US20190271004A1
公开(公告)日：2019-09-05
申请号：US16411671
申请日：2019-05-14
发明人： RAFAEL HERRMANN , MICHAEL LASSNER , ALBERT L. LU , MARK EDWARD NELSON , JAMES KEVIN PRESNAIL , JANET RICE
IPC分类号： C12N15/82 , C12N15/113 , A01N65/44 , A01N65/20
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lepidoptera order, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides target polynucleotides encoding polypeptides from specific protein families and various target polynucleotides set forth in SEQ ID NOS: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, or 50 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Spodoptera frugiperda. Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
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公开(公告)号：US20180338500A1
公开(公告)日：2018-11-29
申请号：US16051554
申请日：2018-08-01
摘要： Entomopathogenic fungal strains, compositions, and methods of using the strains for reducing overall insect damage.
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公开(公告)号：US20200231985A1
公开(公告)日：2020-07-23
申请号：US16839691
申请日：2020-04-03
发明人： XU HU , BLISS MARIE KERNODLE , MOLLIE MARY MCMAHON , ADANE KASSA , XIPING NIU , JAMES KEVIN PRESNAIL , ALBERT L LU , NINA RICHTMAN , JONATHAN WILLIAM ROBESON
IPC分类号： C12N15/82 , A01N63/30 , A01N63/10 , A01N65/00 , A01N37/46 , C07K14/435 , C12N15/113
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-53 or 107-254 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest and pest population by insect sterilization (i.e., male and female sterility, reduction of sperm count, egg production and viability) and mating-based sterile insect technique (SIT). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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公开(公告)号：US20180220658A1
公开(公告)日：2018-08-09
申请号：US15949348
申请日：2018-04-10
CPC分类号： A01N63/04 , A01N25/00 , A01N25/30 , A01N43/36 , A01N43/54 , A01N43/78 , A01N63/00 , A01N37/46 , A01N43/56 , A01N43/653 , A01N2300/00
摘要： Entomopathogenic fungal strains, compositions, and methods of using the strains for reducing overall insect damage.
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公开(公告)号：US20180030472A1
公开(公告)日：2018-02-01
申请号：US15730315
申请日：2017-10-11
发明人： KAREN E. BROGLIE , DAVID CHARLES CERF , RAFAEL HERRMANN , ALBERT L. LU , BRIAN MCGONIGLE , JAMES KEVIN PRESNAIL
IPC分类号： C12N15/82 , A01N65/44 , A01N57/16 , C12N15/113 , A01N65/00
CPC分类号： C12N15/8286 , A01N57/16 , A01N65/00 , A01N65/44 , C12N15/113 , C12N15/8218 , C12N2310/14 , C12N2310/531 , Y02A40/162
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Pentatomidae plant pest or a N. viridula, Acrosternum hilare, Piezodorus guildini, and/or Halymorpha halys plant pest, decrease the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 1-292 or 302-304 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Pentatomidae. Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
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10.发明申请公开(公告)号：US20170175133A1
公开(公告)日：2017-06-22
申请号：US15446107
申请日：2017-03-01
发明人： RAFAEL HERRMANN , MICHAEL LASSNER , ALBERT L. LU , MARK EDWARD NELSON , JAMES KEVIN PRESNAIL , JANET A. RICE
IPC分类号： C12N15/82 , A01N65/44 , A01N65/20 , C12N15/113
CPC分类号： C12N15/8286 , A01N65/20 , A01N65/44 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12N2310/531 , C12N2320/32 , Y02A40/162
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lepidoptera order, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides target polynucleotides encoding polypeptides from specific protein families and various target polynucleotides set forth in SEQ ID NOS: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, or 50 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Spodoptera frugiperda. Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
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