公开(公告)号：US20190059737A1

公开(公告)日：2019-02-28

申请号：US15893877

申请日：2018-02-12

Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION

Inventor： Seunghun LEE ,  Ki Hean Kim ,  Jun Ho Lee ,  Bumju Kim ,  Byung Ho Oh ,  Myoung Joon Kim ,  Kyo Han Anh ,  Hoon Cheol Jang ,  Won Hyuk Jang

IPC: A61B5/00 ,  A61B1/00 ,  A61B1/06 ,  A61B1/313 ,  A61B3/10 ,  A61B5/08 ,  A61B5/20 ,  A61K49/00

Abstract: Disclosed are an imaging method using fluoroquinolone antibiotics and an imaging device for the same, in which biological tissue is stained with Moxifloxacin as one of fluoroquinolone antibiotics, and the stained biological tissue is subjected to fluorescent image-capture through single-photon excitation with either near-ultraviolet or visible wavelength light instead of either a middle-ultraviolet light source or a femtosecond near-infrared laser device, thereby obtaining morphological information of cells in the biological tissue at a high speed without damage. To this end, an imaging method of using fluoroquinolone antibiotics includes: staining cells of the biological tissue with fluoroquinolone antibiotics; illuminating the excitation light from a light source to the biological tissue stained with the fluoroquinolone antibiotics; and capturing an image of the biological tissue through the fluoroquinolone antibiotics based fluorescence caused by the excitation light illuminated to the biological tissue, wherein the excitation light from the light source includes either near-violet or short visible wavelength light for single photon excitation of the fluoroquinolone antibiotics.