-
公开(公告)号：US06346270B1
公开(公告)日：2002-02-12
申请号：US09587686
申请日：2000-06-05
IPC分类号： A61K924
CPC分类号： A61K9/0004 , A61K31/4166
摘要： A therapeutic composition, a dosage form and a method are disclosed for administering phenytoin indicated for the management of epilepsy.
摘要翻译： 公开了治疗组合物，剂型和方法，用于施用用于治疗癫痫的苯妥英。
-
公开(公告)号：US06110499A
公开(公告)日：2000-08-29
申请号：US119382
申请日：1998-07-20
IPC分类号： A61K9/00 , A61K31/4166 , A61K9/24
CPC分类号： A61K9/0004 , A61K31/4166
摘要： A therapeutic composition, a dosage form and a method are disclosed for administering phenytoin indicated for the management of epilepsy.
-
公开(公告)号：US09029416B2
公开(公告)日：2015-05-12
申请号：US10638977
申请日：2003-08-12
申请人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Zahedeh Hatamkhany , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Richard G. Weyers
发明人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Zahedeh Hatamkhany , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Richard G. Weyers
IPC分类号： A61K9/20 , A61K9/00 , A61K9/24 , A61K9/50 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458
CPC分类号： A61K9/2086 , A61K9/0002 , A61K9/0004 , A61K9/2072 , A61K9/209 , A61K9/5084 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458
摘要： Methods and devices for maintaining a desired therapeutic drug effect over a prolonged therapy period are provided. In particular, oral dosage forms that release drug within the gastrointestinal tract at an ascending release rate over an extended time period are provided. The dosage forms may additionally comprise an immediate-release dose of drug.
-
公开(公告)号：US06930129B2
公开(公告)日：2005-08-16
申请号：US09802709
申请日：2001-03-08
申请人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Zahedeh Hatamkhany , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Richard G. Weyers
发明人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Zahedeh Hatamkhany , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Richard G. Weyers
IPC分类号： A61K9/00 , A61K9/20 , A61K9/24 , A61K9/50 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458 , A61K31/235
CPC分类号： A61K9/2086 , A61K9/0002 , A61K9/0004 , A61K9/2072 , A61K9/209 , A61K9/5084 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458
摘要： Methods and devices for maintaining a desired therapeutic drug effect over a prolonged therapy period are provided. In particular, oral dosage forms that release drug within the gastrointestinal tract at an ascending release rate over an extended time period are provided. The dosage forms may additionally comprise an immediate-release dose of drug.
摘要翻译： 提供了用于在延长的治疗期间维持期望的治疗药物作用的方法和装置。 特别地，提供了在延长的时间段内以升高释放速率在胃肠道内释放药物的口服剂型。 剂型还可包含立即释放剂量的药物。
-
公开(公告)号：US06919373B1
公开(公告)日：2005-07-19
申请号：US09253317
申请日：1999-02-19
申请人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Richard G. Weyers , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Zahedeh Hatamkhany
发明人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Richard G. Weyers , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Zahedeh Hatamkhany
IPC分类号： A61K9/00 , A61K9/20 , A61K9/24 , A61K9/50 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458 , A61K31/235
CPC分类号： A61K9/2086 , A61K9/0002 , A61K9/0004 , A61K9/2072 , A61K9/209 , A61K9/5084 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458
摘要： Methods and devices for maintaining a desired therapeutic drug effect over a prolonged therapy period are provided. In particular, oral dosage forms that release drug within the gastrointestinal tract at an ascending release rate over an extended time period are provided. The dosage forms may additionally comprise an immediate-release dose of drug.
-
公开(公告)号：US20120251590A1
公开(公告)日：2012-10-04
申请号：US13436727
申请日：2012-03-30
申请人： Evangeline Cruz , Atul D. Ayer , Brenda J. Pollock , Carmelita Garcia , Sherry Li , Alfredo M. Wong , Lawrence G. Hamel , Cheri Enders Klein , Yihong Qiu , Ye Huang
发明人： Evangeline Cruz , Atul D. Ayer , Brenda J. Pollock , Carmelita Garcia , Sherry Li , Alfredo M. Wong , Lawrence G. Hamel , Cheri Enders Klein , Yihong Qiu , Ye Huang
IPC分类号： A61K9/00 , A61P25/04 , A61P29/00 , A61K31/485
CPC分类号： A61K9/2086 , A61K9/0004 , A61K9/209 , A61K9/4808 , A61K9/5084 , A61K31/00 , A61K31/16 , A61K31/165 , A61K31/167 , A61K31/485 , A61K45/06 , A61K2300/00
摘要： Sustained release dosage forms for twice daily oral dosing to a human patient for providing relief from pain are provided. The sustained release dosage form comprises an immediate release component and a sustained release component, wherein the immediate release component and the sustained release component collectively contain a therapeutically effective amount of an opioid analgesic and a therapeutically effective amount of nonopioid analgesic.
摘要翻译： 提供了持续释放剂型，每天两次口服给予患者以缓解疼痛。 持续释放剂型包括速释组分和持续释放组分，其中速释组分和持续释放组分共同含有治疗有效量的阿片样镇痛剂和治疗有效量的非阿片类止痛剂。
-
7.发明授权公开(公告)号：US06630165B2
公开(公告)日：2003-10-07
申请号：US10087026
申请日：2002-02-28
申请人： Sylvia L. Seroff , Noymi V. Yam , Atul D. Ayer , Padmanabh P. Bhatt , Michael A. Desjardin , Andrew C. Lam , David E. Edgren , Phillip R. Nixon
发明人： Sylvia L. Seroff , Noymi V. Yam , Atul D. Ayer , Padmanabh P. Bhatt , Michael A. Desjardin , Andrew C. Lam , David E. Edgren , Phillip R. Nixon
IPC分类号： A61K924
CPC分类号： A61K31/5375 , A61K9/0004
摘要： Dosage forms and methods for providing sustained release of reboxetine are provided. The sustained release dosage forms provide therapeutically effective average steady-state plasma reboxetine concentrations when administered once per day. This once-a-day dosing regimen results in only one peak plasma reboxetine concentration occurrence in each 24 hour period. In addition, the peak plasma reboxetine concentration occurs at a later time following dose administration and exhibits a lesser magnitude than the peak plasma reboxetine concentration that occurs following administration of reboxetine in an immediate-release dosage form.
摘要翻译： 提供了用于提供瑞波西汀持续释放的剂型和方法。 当每天施用一次时，缓释剂型提供治疗有效的平均稳态血浆瑞波西汀浓度。 这种每天一次的给药方案导致每24小时内出现一种峰值血浆瑞波西汀浓度。 此外，血浆瑞波西汀峰浓度发生在剂量给药后的稍后时间，并且呈现比在立即释放剂型中施用瑞波西汀后发生的峰值血浆瑞波西汀浓度更小的量值。
-
公开(公告)号：US06534089B1
公开(公告)日：2003-03-18
申请号：US09602916
申请日：2000-06-23
IPC分类号： A61K922
CPC分类号： A61K9/0004
摘要： The invention disclosed pertains to a novel delivery system comprising an agent formulation and means for dispensing the agent formulation from the delivery system.
-
9.发明授权Dosage forms and methods for providing effective reboxetine therapy with once-a-day dosing 有权剂量形式和方法，每天给药一次提供有效的瑞波西汀治疗公开(公告)号：US06387403B1
公开(公告)日：2002-05-14
申请号：US09661976
申请日：2000-09-14
申请人： Sylvia L. Seroff , Noymi V. Yam , Atul D. Ayer , Padmanabh P. Bhatt , Michael A. Desjardin , Andrew C. Lam , David E. Edgren , Phillip R. Nixon
发明人： Sylvia L. Seroff , Noymi V. Yam , Atul D. Ayer , Padmanabh P. Bhatt , Michael A. Desjardin , Andrew C. Lam , David E. Edgren , Phillip R. Nixon
IPC分类号： A61K924
CPC分类号： A61K31/5375 , A61K9/0004
摘要： Dosage forms and methods for providing sustained release of reboxetine are provided. The sustained release dosage forms provide therapeutically effective average steady-state plasma reboxetine concentrations when administered once per day. This once-a-day dosing regimen results in only one peak plasma reboxetine concentration occurrence in each 24 hour period. In addition, the peak plasma reboxetine concentration occurs at a later time following dose administration and exhibits a lesser magnitude than the peak plasma reboxetine concentration that occurs following administration of reboxetine in an immediate-release dosage form.
摘要翻译： 提供了用于提供瑞波西汀持续释放的剂型和方法。 当每天施用一次时，缓释剂型提供治疗有效的平均稳态血浆瑞波西汀浓度。 这种每天一次的给药方案导致每24小时内出现一种峰值血浆瑞波西汀浓度。 此外，血浆瑞波西汀峰浓度发生在剂量给药后的稍后时间，并且呈现比在立即释放剂型中施用瑞波西汀后发生的峰值血浆瑞波西汀浓度更小的量值。
-
公开(公告)号：US5948787A
公开(公告)日：1999-09-07
申请号：US808147
申请日：1997-02-28
申请人： Sonya Merrill , Atul D. Ayer , Paul M. Hwang , Anthony L. Kuczynski , Nils W. Ahlgren , Deborah J. Johnson
发明人： Sonya Merrill , Atul D. Ayer , Paul M. Hwang , Anthony L. Kuczynski , Nils W. Ahlgren , Deborah J. Johnson
IPC分类号： A61K9/00 , A61K9/20 , A61K9/22 , A61K31/485
CPC分类号： A61K9/2054 , A61K31/485 , A61K9/0004 , A61K9/2009 , A61K9/2027 , A61K9/2031
摘要： An opiate analgesic composition and a non-opiate analgesic composition are disclosed for delivering an analgesic in either embodiment to a patient in need of relief from pain. The analgesics are present optionally with a nonionic surfactant and with an osmotic composition comprising a carbonate or bicarbonate for delivering the opiate analgesic and non-opiate analgesic from a dosage form.
摘要翻译： 公开了一种阿片镇痛组合物和非阿片类镇痛组合物，用于在任一实施方案中将镇痛剂递送至需要缓解疼痛的患者。 止痛剂任选地含有非离子表面活性剂和包含碳酸盐或碳酸氢盐的渗透组合物，用于从剂型中输送阿片剂镇痛药和非阿片类止痛剂。
-
-
-
-
-
-
-
-
-
搜索结果
80 条记录 (耗时 0.042 秒)
