公开(公告)号：US06653350B1

公开(公告)日：2003-11-25

申请号：US09390440

申请日：1999-09-07

申请人： Pamela T. Manning ,  Jane R. Connor ,  Mark G. Currie ,  Jean Pierre Pelletier ,  Johanne Martel Pelletier

发明人： Pamela T. Manning ,  Jane R. Connor ,  Mark G. Currie ,  Jean Pierre Pelletier ,  Johanne Martel Pelletier

IPC分类号： A61K31195

CPC分类号： A61K31/198 ,  A61K31/00

摘要： Methods of treating osteoarthritis by administering an therapeutically effective amount of NOS inhibitor are provided.

摘要翻译： 提供了通过施用治疗有效量的NOS抑制剂治疗骨关节炎的方法。

公开(公告)号：US07555153B2

公开(公告)日：2009-06-30

申请号：US11003970

申请日：2004-12-03

申请人： Johanne Martel-Pelletier ,  Jean Pierre Pelletier ,  Fabrice Ganansia ,  Françoys Labonté ,  François Abram ,  Jean-Pierre Raynauld

发明人： Johanne Martel-Pelletier ,  Jean Pierre Pelletier ,  Fabrice Ganansia ,  Françoys Labonté ,  François Abram ,  Jean-Pierre Raynauld

IPC分类号： G06K9/00 ,  A61K35/34 ,  A61F2/30

CPC分类号： A61B5/4514 ,  A61B5/055 ,  A61B5/103 ,  A61B5/1075 ,  A61B5/4528 ,  G06F19/00 ,  G06T7/0012 ,  G06T2207/30008

摘要： Disclosed, in one general aspect, is a musculoskeletal imaging system that includes a source of feature data extracted from imaging data resulting from imaging acquisitions from joints of different individuals affected by different diseases, and this feature data includes disease characteristic categorization information for a plurality of disease categories. A comparison module is operative to compare patient imaging data resulting from an imaging acquisition from a joint of a patient with the feature data. The comparison module is also operative to provide at least one categorization indicator for the patient imaging data that indicates a correspondence between spatial information in the patient imaging data and the disease categories for which there is extracted categorization information in the feature data.

摘要翻译： 在一个一般方面，公开了一种肌肉骨骼成像系统，其包括从由不同疾病受影响的不同个体的关节的成像采集产生的成像数据中提取的特征数据源，并且该特征数据包括用于不同疾病的疾病特征分类信息 疾病类别。 比较模块用于将来自患者的关节的成像获取产生的患者成像数据与特征数据进行比较。 比较模块还可操作以提供用于指示患者成像数据中的空间信息与在特征数据中提取分类信息的疾病类别之间的对应关系的患者成像数据的至少一个分类指示符。

公开(公告)号：US06901280B2

公开(公告)日：2005-05-31

申请号：US10430800

申请日：2003-05-06

申请人： Jean Pierre Pelletier ,  Johanne Martel-Pelletier ,  M. Jacques de Guise ,  Jean-Pierre Raynauld ,  Marie-Josee Barthiaume ,  Gilles Beaudoin ,  M. Benoit Godbout ,  M. Claude Kauffmann

发明人： Jean Pierre Pelletier ,  Johanne Martel-Pelletier ,  M. Jacques de Guise ,  Jean-Pierre Raynauld ,  Marie-Josee Barthiaume ,  Gilles Beaudoin ,  M. Benoit Godbout ,  M. Claude Kauffmann

IPC分类号： G01R33/56 ,  G06T5/50 ,  G06T7/00 ,  A61B5/05

CPC分类号： G01R33/56 ,  A61B5/4504 ,  A61B5/4514 ,  A61B5/4528 ,  G01R33/5608 ,  G06T5/50 ,  G06T7/0012

摘要： An orthopedic magnetic resonance imaging system is disclosed. This system includes a source of magnetic resonance imaging data sets resulting from successive magnetic resonance imaging acquisitions from a diseased joint of a patient. A segmentation module segments surfaces in the joint based on information contained within at least one of the data sets, and a registration module spatially registers, in three dimensions, information represented by a first of the data sets with respect to information represented by one or more further data sets for the same patient. A comparison module detects differences between information represented by the data sets caused by progression of the disease in the joint of the patient between acquisitions. A cross-patient comparison module can compare detected differences for the patient with detected differences for at least one other patient.

公开(公告)号：US20050085709A1

公开(公告)日：2005-04-21

申请号：US11003620

申请日：2004-12-03

申请人： Jean Pierre Pelletier ,  Johane Pelletier ,  Jacques de Guise ,  Jean-Pierre Raynauld ,  Marie-Josee Barthiaume ,  Gilles Beaudoin ,  Benoit Godbout ,  Claude Kauffmann

发明人： Jean Pierre Pelletier ,  Johane Pelletier ,  Jacques de Guise ,  Jean-Pierre Raynauld ,  Marie-Josee Barthiaume ,  Gilles Beaudoin ,  Benoit Godbout ,  Claude Kauffmann

IPC分类号： G01R33/56 ,  G06T5/50 ,  G06T7/00 ,  A61B5/05 ,  G06K9/00

CPC分类号： G01R33/56 ,  A61B5/4504 ,  A61B5/4514 ,  A61B5/4528 ,  G01R33/5608 ,  G06T5/50 ,  G06T7/0012

摘要： An orthopedic magnetic resonance imaging system is disclosed. This system includes a source of magnetic resonance imaging data sets resulting from successive magnetic resonance imaging acquisitions from a diseased joint of a patient. A segmentation module segments surfaces in the joint based on information contained within at least one of the data sets, and a registration module spatially registers, in three dimensions, information represented by a first of the data sets with respect to information represented by one or more further data sets for the same patient. A comparison module detects differences between information represented by the data sets caused by progression of the disease in the joint of the patient between acquisitions. A cross-patient comparison module can compare detected differences for the patient with detected differences for at least one other patient.

公开(公告)号：US06560476B1

公开(公告)日：2003-05-06

申请号：US09704269

申请日：2000-11-01

申请人： Jean Pierre Pelletier ,  Johane Pelletier ,  M. Jacques de Guise ,  Jean-Pierre Raynauld ,  Marie-Josee Barthiaume ,  Gilles Beaudoin ,  M. Benoit Godbout ,  M. Claude Kauffmann

发明人： Jean Pierre Pelletier ,  Johane Pelletier ,  M. Jacques de Guise ,  Jean-Pierre Raynauld ,  Marie-Josee Barthiaume ,  Gilles Beaudoin ,  M. Benoit Godbout ,  M. Claude Kauffmann

IPC分类号： A61B505

CPC分类号： G01R33/56 ,  A61B5/4504 ,  A61B5/4514 ,  A61B5/4528 ,  G01R33/5608 ,  G06T5/50 ,  G06T7/0012

摘要： An orthopedic magnetic resonance imaging system is disclosed. This system includes a source of magnetic resonance imaging data sets resulting from successive magnetic resonance imaging acquisitions from a diseased joint of a patient. A segmentation module segments surfaces in the joint based on information contained within at least one of the data sets, and a registration module spatially registers, in three dimensions, information represented by a first of the data sets with respect to information represented by one or more further data sets for the same patient. A comparison module detects differences between information represented by the data sets caused by progression of the disease in the joint of the patient between acquisitions. A cross-patient comparison module can compare detected differences for the patient with detected differences for at least one other patient.

摘要翻译： 公开了一种矫形磁共振成像系统。 该系统包括由来自病人的病变关节的连续磁共振成像获取产生的磁共振成像数据集的源。 分割模块基于包含在至少一个数据集中的信息来分割关节中的表面，并且注册模块以三维空间方式登记由第一数据集表示的关于由一个或多个 同一病人的其他数据集。 比较模块检测由收购之间的患者联合中疾病进展引起的数据集所代表的信息之间的差异。 交叉患者比较模块可以将患者的检测到的差异与至少一个其他患者的检测到的差异进行比较。