专利检索 ap:("Paola Concari" OR "Matthias Herrmann" OR "Jochen Kruip" OR "Thomas Leeuw" OR "Alexander Rueck") AND inv:"Paola Concari" 第 1 页

1.

发明申请
USE OF THE MST PROTEIN FOR THE TREATMENT OF A THROMBOEMBOLIC DISORDER 审中-公开
标题翻译：使用MST蛋白治疗血栓性疾病

公开(公告)号：US20090149375A1

公开(公告)日：2009-06-11

申请号：US11908467

申请日：2006-03-20

申请人： Paola Concari , Matthias Herrmann , Jochen Kruip , Thomas Leeuw , Alexander Rueck

发明人： Paola Concari , Matthias Herrmann , Jochen Kruip , Thomas Leeuw , Alexander Rueck

IPC分类号： A61K38/16 , A61K31/7088 , C12Q1/68 , C12Q1/48 , C40B30/00

CPC分类号： A61K38/45

摘要： The present invention refers to the use of the Mst protein or a nucleotide sequence coding for the Mst protein for the treatment of a thromboembolic disorder and to a method of screening a modulator of the Mst protein or the nucleotide sequence coding for the Mst protein.

摘要翻译： 本发明涉及使用Mst蛋白或编码Mst蛋白的核苷酸序列来治疗血栓栓塞性疾病，以及筛选Mst蛋白的调节剂或编码Mst蛋白的核苷酸序列的方法。

2.

发明授权
C. elegans p21-activated kinase (PAK) gene and associated loss-of-function phenotypes that facilitate screening for small molecule modulators of PAK activity in the nematode, caenorhabditis elegans 失效
标题翻译： C.线虫p21激活的激酶（PAK）基因和相关的功能丧失表型，有助于筛选线虫，秀丽隐杆线虫中PAK活性的小分子调节剂

公开(公告)号：US07319024B1

公开(公告)日：2008-01-15

申请号：US11045439

申请日：2005-01-28

申请人： Kaj Grandien , Jonathan Rothblatt , Paola Concari , Isabelle Quelo , Bert Klebl

发明人： Kaj Grandien , Jonathan Rothblatt , Paola Concari , Isabelle Quelo , Bert Klebl

IPC分类号： C12P19/34 , C12N1/20 , C12N15/00 , C07H21/04

CPC分类号： C12N15/1137 , A01K67/0336 , A01K2217/075 , A01K2227/703 , A01K2267/0331 , C07K14/43545 , C12N9/1205 , C12N2310/14

摘要： The invention refers to a novel C. elegans p21-activated kinase gene, the pak-3 gene, and associated loss-of-function phenotypes. These phenotypes can be used to elucidate PAK signaling pathways in C. elegans and to screen compounds that modulate PAK signaling.

摘要翻译： 本发明涉及一种新颖的秀丽隐杆线虫p21激活的激酶基因，pak-3基因和相关的功能丧失表型。这些表型可用于阐明秀丽隐杆线虫中的PAK信号通路，并筛选调节PAK信号传导的化合物。