公开(公告)号：US20090024187A1

公开(公告)日：2009-01-22

申请号：US12243632

申请日：2008-10-01

申请人： John H. Erickson ,  George Van Campen ,  Patrick M. Cullen ,  Thomas K. Hickman

发明人： John H. Erickson ,  George Van Campen ,  Patrick M. Cullen ,  Thomas K. Hickman

IPC分类号： A61N1/36

CPC分类号： A61N1/37247 ,  A61N1/36017 ,  A61N1/3605 ,  A61N1/37241

摘要： Disclosed are systems and methods which provide trial stimulators suited for use interoperatively and during patient trial. Trial stimulator embodiments provide a patient interface and/or clinician interface which appears and functions substantially the same as an interface of a pulse generator controller which will be used after a trial period. A compliance monitor feature may be provided to facilitate verifying the proper use of the trial stimulator during a trial period. A diagnostic feature may be provided to facilitate verifying proper operation of various aspects of a trial stimulator, such as electrode impedance analysis. Trial stimulators of embodiments provide stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera. Embodiments provide for multi-electrode stimulation and multi-stimulation programs. Embodiments are configured to provide active discharge of stimulation pulses as well as to utilize constant current sources in providing the stimulation pulses.

摘要翻译： 公开了提供适合于在手术期间和在患者试验期间使用的试验刺激物的系统和方法。 试验刺激器实施例提供患者接口和/或临床医师界面，该接口出现并且功能基本上与在试用期之后使用的脉冲发生器控制器的接口相同。 可以提供合规监测功能以便于在试用期间验证试用刺激器的正确使用。 可以提供诊断特征以便于验证试验刺激器的各个方面的正确操作，例如电极阻抗分析。 实施例的刺激器可以对身体的多个组织和/或区域提供刺激，例如脊髓刺激，深部脑刺激等。 实施例提供多电极刺激和多刺激程序。 实施例被配置为提供刺激脉冲的主动放电以及在提供刺激脉冲时利用恒定电流源。

公开(公告)号：US08340775B1

公开(公告)日：2012-12-25

申请号：US12423124

申请日：2009-04-14

申请人： Patrick M. Cullen ,  John H. Erickson

发明人： Patrick M. Cullen ,  John H. Erickson

IPC分类号： A61N1/00

CPC分类号： A61N1/36128 ,  A61N1/05 ,  A61N1/0553 ,  A61N1/36178 ,  A61N1/37247 ,  G06F19/00 ,  G16H40/63

摘要： In one embodiment, a method for defining a stimulation program for electrical stimulation of a patient, the method comprising: providing a single screen user interface that comprises a first plurality of controls and a second plurality of controls, the first plurality of controls allowing selection of multiple stimulation parameters for a plurality of stimulation sets, the second plurality of controls allowing selection of multiple stimulation parameters defining burst stimulation and tonic stimulation; receiving user input in one or more of the second plurality of controls; and automatically modifying parameters for one or more stimulation sets in response to receiving the user input in one or more of the second plurality of controls and modifying values displayed in one or more controls of the first plurality of controls according to the modified parameters, the modified parameters reflecting a stimulation program that includes an interleaved pattern of burst stimulation and tonic stimulation for delivery to the patient.

摘要翻译： 在一个实施例中，一种用于定义用于电刺激患者的刺激程序的方法，所述方法包括：提供包括第一多个控制和第二多个控制的单个屏幕用户界面，所述第一多个控件允许选择 用于多个刺激组的多个刺激参数，所述第二多个控制允许选择限定突发刺激和强直刺激的多个刺激参数; 在所述第二多个控制中的一个或多个中接收用户输入; 以及响应于在所述第二多个控制中的一个或多个控制中接收到所述用户输入并根据所述修改的参数修改显示在所述第一多个控件的一个或多个控制中的值，自动修改针对一个或多个刺激集的参数， 反映刺激程序的参数，其包括突发刺激的交替模式和用于递送给患者的补品刺激。

公开(公告)号：US20110208265A1

公开(公告)日：2011-08-25

申请号：US13099142

申请日：2011-05-02

申请人： John H. Erickson ,  George Van Campen ,  Patrick M. Cullen ,  Thomas K. Hickman

发明人： John H. Erickson ,  George Van Campen ,  Patrick M. Cullen ,  Thomas K. Hickman

IPC分类号： A61N1/36

CPC分类号： A61N1/37247 ,  A61N1/36017 ,  A61N1/3605 ,  A61N1/37241

摘要： Disclosed are systems and methods which provide trial stimulators suited for use interoperatively and during patient trial. Trial stimulator embodiments provide a patient interface and/or clinician interface which appears and functions substantially the same as an interface of a pulse generator controller which will be used after a trial period. A compliance monitor feature may be provided to facilitate verifying the proper use of the trial stimulator during a trial period. A diagnostic feature may be provided to facilitate verifying proper operation of various aspects of a trial stimulator, such as electrode impedance analysis. Trial stimulators of embodiments provide stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera. Embodiments provide for multi-electrode stimulation and multi-stimulation programs. Embodiments are configured to provide active discharge of stimulation pulses as well as to utilize constant current sources in providing the stimulation pulses.

摘要翻译： 公开了提供适合于在手术期间和在患者试验期间使用的试验刺激物的系统和方法。 试验刺激器实施例提供了患者接口和/或临床医生界面，该接口出现并且与在试用期之后将被使用的脉冲发生器控制器的接口基本相同。 可以提供合规监测功能以便于在试用期间验证试用刺激器的正确使用。 可以提供诊断特征以便于验证试验刺激器的各个方面的正确操作，例如电极阻抗分析。 实施例的刺激器可以对身体的多个组织和/或区域提供刺激，例如脊髓刺激，深部脑刺激等。 实施例提供多电极刺激和多刺激程序。 实施例被配置为提供刺激脉冲的主动放电以及在提供刺激脉冲时利用恒定电流源。

公开(公告)号：US07359751B1

公开(公告)日：2008-04-15

申请号：US11122706

申请日：2005-05-05

申请人： John H. Erickson ,  George Van Campen ,  Patrick M. Cullen ,  Thomas K. Hickman

发明人： John H. Erickson ,  George Van Campen ,  Patrick M. Cullen ,  Thomas K. Hickman

IPC分类号： A61N1/08

CPC分类号： A61N1/37247 ,  A61N1/36017 ,  A61N1/3605 ,  A61N1/37241

摘要： Disclosed are systems and methods which provide an external clinician interface, such as through the use of a laptop computer or a personal digital assistant (PDA). The foregoing clinician interface may be used with trial stimulators well suited for use interoperatively and during patient trial. Stimulators of embodiments are adapted for use in providing stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera.

摘要翻译： 公开了提供外部临床医师界面的系统和方法，例如通过使用膝上型计算机或个人数字助理（PDA）。 上述临床医师界面可以与试验刺激器一起使用，其非常适合于在手术中和在患者试验期间使用。 实施例的刺激器适于用于向身体的多个组织和/或区域提供刺激，例如脊髓刺激，深部脑刺激等。

公开(公告)号：US08571685B2

公开(公告)日：2013-10-29

申请号：US13549803

申请日：2012-07-16

申请人： Terry Daglow ,  Brian Franz ,  John H. Erickson ,  Sandy Hooper ,  Tim Jones

发明人： Terry Daglow ,  Brian Franz ,  John H. Erickson ,  Sandy Hooper ,  Tim Jones

IPC分类号： A61N1/00

CPC分类号： A61N1/0551 ,  A61N1/0529

摘要： A lead, method of manufacturing same, and system for stimulation is provided. The lead includes an insulative member or layer that masks a portion of the electrode(s) to effectively generate a directional lead that focuses or directs the stimulation to desired location(s). In another embodiment, the lead further includes a marking system to allow a clinician to orient the directional lead, as desired, while the lead is within a body.

摘要翻译： 提供铅，制造方法和刺激系统。 引线包括掩蔽电极的一部分的绝缘构件或层，以有效地产生将刺激聚焦或引导到所需位置的方向引线。 在另一个实施例中，引线还包括标记系统，以允许临床医生在引线位于身体内时根据需要定向方向引线。

公开(公告)号：US08543218B2

公开(公告)日：2013-09-24

申请号：US13663145

申请日：2012-10-29

申请人： John H. Erickson

发明人： John H. Erickson

IPC分类号： A61N1/00

CPC分类号： A61N1/37 ,  A61N1/086 ,  A61N1/3718

摘要： In one embodiment, a pulse generator for generating electrical stimulation for delivery to a patient, comprises: a hermetically sealed housing containing pulse generating circuitry; a header coupled to the housing for receiving one or more stimulation leads, wherein feedthrough wires are provided to conduct electrical pulses from the pulse generating circuitry to the header; the header comprising a plurality of connectors for electrically connecting to each terminal of the one or more stimulation leads, wherein an inductive winding is disposed around or adjacent to each of the connector structures and is electrically connected between the respective connector structure and a corresponding feedthrough wire to limit MRI induced heating of a respective electrode of the one or more stimulation leads.

摘要翻译： 在一个实施例中，用于产生用于递送给患者的电刺激的脉冲发生器包括：包含脉冲发生电路的密封外壳; 连接到所述壳体以用于接收一个或多个刺激引线的头部，其中提供穿通线以将电脉冲从所述脉冲发生电路传导到所述头部; 所述头部包括用于电连接到所述一个或多个刺激引线的每个端子的多个连接器，其中感应绕组设置在每个所述连接器结构的周围或附近，并且电连接在相应的连接器结构和相应的馈通线 以限制一个或多个刺激引线的相应电极的MRI诱导加热。

公开(公告)号：US20130013039A1

公开(公告)日：2013-01-10

申请号：US13549803

申请日：2012-07-16

申请人： Terry Daglow ,  Brian Franz ,  John H. Erickson ,  Sandy Hooper ,  Tim Jones

发明人： Terry Daglow ,  Brian Franz ,  John H. Erickson ,  Sandy Hooper ,  Tim Jones

IPC分类号： A61N1/05

CPC分类号： A61N1/0551 ,  A61N1/0529

摘要： A lead, method of manufacturing same, and system for stimulation is provided. The lead includes an insulative member or layer that masks a portion of the electrode(s) to effectively generate a directional lead that focuses or directs the stimulation to desired location(s). In another embodiment, the lead further includes a marking system to allow a clinician to orient the directional lead, as desired, while the lead is within a body.

摘要翻译： 提供铅，制造方法和刺激系统。 引线包括掩蔽电极的一部分的绝缘构件或层，以有效地产生将刺激聚焦或引导到所需位置的方向引线。 在另一个实施例中，引线还包括标记系统，以允许临床医生在引线位于身体内时根据需要定向方向引线。

公开(公告)号：US08315715B2

公开(公告)日：2012-11-20

申请号：US13540361

申请日：2012-07-02

申请人： John H. Erickson

发明人： John H. Erickson

IPC分类号： A61N1/00

CPC分类号： A61N1/37 ,  A61N1/086 ,  A61N1/3718

摘要： In one embodiment, a pulse generator for generating electrical stimulation for delivery to a patient, comprises: a hermetically sealed housing containing pulse generating circuitry; a header coupled to the housing for receiving one or more stimulation leads, wherein feedthrough wires are provided to conduct electrical pulses from the pulse generating circuitry to the header; the header comprising a plurality of connectors for electrically connecting to each terminal of the one or more stimulation leads, wherein an inductive winding is disposed around or adjacent to each of the connector structures and is electrically connected between the respective connector structure and a corresponding feedthrough wire to limit MRI induced heating of a respective electrode of the one or more stimulation leads.

公开(公告)号：US20110313489A1

公开(公告)日：2011-12-22

申请号：US13180243

申请日：2011-07-11

申请人： John H. Erickson

发明人： John H. Erickson

IPC分类号： A61N1/08

CPC分类号： A61N1/378 ,  A61N1/3708 ,  A61N1/40

摘要： The invention relates to a stimulation device for creating complex or multi-purpose tissue stimulation. Many typical stimulation devices suffer from deficiencies in providing complex stimulation patterns. Using a circuitry operable or programmable to repeat and skip stimulation settings, a complex stimulation set may be created. The repeating and skipping functionality may be implemented in hardware or software. In this manner, complex stimulations may be derived from simple circuitries. Furthermore, these stimulations may be used to treat pain, stimulate bone growth, and control motor disorders, among others.

摘要翻译： 本发明涉及一种用于产生复合或多用途组织刺激的刺激装置。 许多典型的刺激装置在提供复杂刺激模式方面存在缺陷。 使用可操作或可编程的电路来重复和跳过刺激设置，可以创建复杂的刺激集合。 重复和跳过功能可以在硬件或软件中实现。 以这种方式，可以从简单的电路中导出复杂的刺激。 此外，这些刺激可以用于治疗疼痛，刺激骨骼生长和控制运动障碍等。

公开(公告)号：US07979133B2

公开(公告)日：2011-07-12

申请号：US12578396

申请日：2009-10-13

申请人： Claudio A. Feler ,  John H. Erickson

发明人： Claudio A. Feler ,  John H. Erickson

IPC分类号： A61N1/34

CPC分类号： A61N1/0553 ,  A61N1/36071 ,  A61N1/36185

摘要： In some embodiments, a paddle lead is implanted within a patient such that the electrodes are positioned within the cervical or thoracic spinal levels. An electrode combination on a first row of electrodes can be determined that is effective for a first pain location with minimal effects on other regions of the body. The first pain location can be addressed by stimulating a first dorsal column fiber due to the relatively fine electrical field resolution achievable by the multiple columns. Then, another electrode combination on a second row of electrodes can be determined for a second pain location with minimal effects on other regions. The second pain location could be addressed by stimulating a second dorsal column fiber. After the determination of the appropriate electrodes for stimulation, the patient's IPG can be programmed to deliver pulses using the first and second rows according to the determined electrode combinations.

摘要翻译： 在一些实施例中，将桨引线植入患者体内，使得电极定位在子宫颈或胸部脊柱水平内。 可以确定在第一排电极上的电极组合，对于第一疼痛位置是有效的，对身体的其他区域的影响最小。 可以通过刺激第一背侧列纤维来解决第一个疼痛位置，这是由于多列可实现的相对精细的电场分辨率。 然后，可以确定第二排电极上的另一电极组合用于第二疼痛位置，对其他区域的影响最小。 可以通过刺激第二背侧纤维来解决第二个疼痛位置。 在确定用于刺激的适当电极之后，可以根据所确定的电极组合，将患者的IPG编程为使用第一和第二行递送脉冲。